NR 565 - ADVANCED PHARMACOLOGY MIDTERM
(2025/2026) EXAM – CHAMBERLAIN WITH
COMPLETE QUESTIONS AND CORRECT DETAILED
Page | 1
ANSWERS WITH RATIONALE (EXPERT VERIFIED)
FOR GUARANTEED PASS|TOP RATED A+.
NR 565
During what trimester is a pregnant woman most at risk for
adverse drug reactions with potential long term
consequences? ...... ANSWER ....... 1st trimester (fetus
most at risk d/t rapid growth)
What is BEERS criteria? ...... ANSWER .......
Recommendations of medications inappropriate for elderly
(65 and older), prescriber ultimately decides
What is the CYP450 (cytochrome P450) ...... ANSWER
....... liver enzyme system where medications are
metabolized, can either be inducers or inhibitors and create
drug-drug interactions
CYP450 inducers ...... ANSWER ....... Speed up
metabolism of drugs (drug is cleared faster), drug has lesser
, effect (decrease blood levels of drug), elevate CYP450
enzymes
Page | 2
CYP450 inducers pneumonic ...... ANSWER .......
"Bullshit Crap GPS INDUCES rage"
CYP450 inducer drug names ...... ANSWER .......
Barbituates, St John wort, Carbamazepine, rifampin,
alcohol, phenytoin, griseofulvin, phenobarbital,
sulfonylureas
CYP450 inhibitors ...... ANSWER ....... inhibit
metabolism, increase blood levels of medications
CYP450 pneumonic ...... ANSWER ....... "VISA credit
card debt INHIBITS spending on designers like CK to look
GQ"
CYP450 inhibitors drug names ...... ANSWER .......
Valproate, isoniazid, sulfonamides, amiodarone,
chloramphenicol, ketoconazole, grapefruit juice, quinidine
, Physiological changes during pregnancy that impact
pharmacodynamics and pharmacokinetic properties of drugs?
...... ANSWER ....... increase glomerular filtration rate
Page | 3
leads to increase durg excretion
increase hepatic metabolism
decrease tone and motility of bowel
increase drug absorption
Examples of medications that can be teratogenic ......
ANSWER ....... Antiepileptic drugs, antimicrobials such
as tetracyclines and fluoroquinolones, vitamin A in large
doses, some anticoagulants, and hormonal medications
such as diethylstilbestrol (DES).
How is absorption of intramuscular medications different in
neonates? ...... ANSWER ....... slow and erratic due to
low blood flow in muscles first few days of life
Why is absorption of medication in the stomach increased in
infancy? ...... ANSWER ....... delayed gastric emptying
Some medications that should be avoided in the pediatric
patient? ...... ANSWER ....... glucocorticoids,
, discoloration of developing teeth with tetracyclines, and
kernicterus with sulfonamides, levofloxacin (antibiotics)
Page | 4
aspirin (Severe intoxication from acute overdose)
what should be included in medication administration
patient education? ...... ANSWER ....... dosage size and
timing
route and technique of administration
duration of treatment
drug storage
nature and time course of desired responses
nature and time course of adverse responses
finish taking antibiotic
What are some things that put the elderly patient at higher
risk for adverse drug reactions? ...... ANSWER .......
reduced renal function
polypharmacy (the use of five or more medications daily)
greater severity of illness
presence of comorbidities
(2025/2026) EXAM – CHAMBERLAIN WITH
COMPLETE QUESTIONS AND CORRECT DETAILED
Page | 1
ANSWERS WITH RATIONALE (EXPERT VERIFIED)
FOR GUARANTEED PASS|TOP RATED A+.
NR 565
During what trimester is a pregnant woman most at risk for
adverse drug reactions with potential long term
consequences? ...... ANSWER ....... 1st trimester (fetus
most at risk d/t rapid growth)
What is BEERS criteria? ...... ANSWER .......
Recommendations of medications inappropriate for elderly
(65 and older), prescriber ultimately decides
What is the CYP450 (cytochrome P450) ...... ANSWER
....... liver enzyme system where medications are
metabolized, can either be inducers or inhibitors and create
drug-drug interactions
CYP450 inducers ...... ANSWER ....... Speed up
metabolism of drugs (drug is cleared faster), drug has lesser
, effect (decrease blood levels of drug), elevate CYP450
enzymes
Page | 2
CYP450 inducers pneumonic ...... ANSWER .......
"Bullshit Crap GPS INDUCES rage"
CYP450 inducer drug names ...... ANSWER .......
Barbituates, St John wort, Carbamazepine, rifampin,
alcohol, phenytoin, griseofulvin, phenobarbital,
sulfonylureas
CYP450 inhibitors ...... ANSWER ....... inhibit
metabolism, increase blood levels of medications
CYP450 pneumonic ...... ANSWER ....... "VISA credit
card debt INHIBITS spending on designers like CK to look
GQ"
CYP450 inhibitors drug names ...... ANSWER .......
Valproate, isoniazid, sulfonamides, amiodarone,
chloramphenicol, ketoconazole, grapefruit juice, quinidine
, Physiological changes during pregnancy that impact
pharmacodynamics and pharmacokinetic properties of drugs?
...... ANSWER ....... increase glomerular filtration rate
Page | 3
leads to increase durg excretion
increase hepatic metabolism
decrease tone and motility of bowel
increase drug absorption
Examples of medications that can be teratogenic ......
ANSWER ....... Antiepileptic drugs, antimicrobials such
as tetracyclines and fluoroquinolones, vitamin A in large
doses, some anticoagulants, and hormonal medications
such as diethylstilbestrol (DES).
How is absorption of intramuscular medications different in
neonates? ...... ANSWER ....... slow and erratic due to
low blood flow in muscles first few days of life
Why is absorption of medication in the stomach increased in
infancy? ...... ANSWER ....... delayed gastric emptying
Some medications that should be avoided in the pediatric
patient? ...... ANSWER ....... glucocorticoids,
, discoloration of developing teeth with tetracyclines, and
kernicterus with sulfonamides, levofloxacin (antibiotics)
Page | 4
aspirin (Severe intoxication from acute overdose)
what should be included in medication administration
patient education? ...... ANSWER ....... dosage size and
timing
route and technique of administration
duration of treatment
drug storage
nature and time course of desired responses
nature and time course of adverse responses
finish taking antibiotic
What are some things that put the elderly patient at higher
risk for adverse drug reactions? ...... ANSWER .......
reduced renal function
polypharmacy (the use of five or more medications daily)
greater severity of illness
presence of comorbidities
