BIOL 322 Exam 3
1. Which of the following defines the principle of genetic linkage
a . Two or more genes that are physically connected on a chromosome
b . Genes that are transmitted to the next generation as a group RES
c . The process by which genetic information is exchanged between homologous
chromosomes
d . Both A and B
e . All of the above – answer d . Both A and B
2. While mapping genes in Drosophila , you observe 35 recombinants among 437 total
offspring . What is the distance between these genes ?
a . 26 map units
c . 12 map units
b . 18 map units
d . 8 map units
3. Convert that number to centimorgans . - answer2. d . 8 map units
3. 8 cM
4. T / F the answer you obtained # 2 is an accurate hypothesis for the distance , no
other forces influence the number of recombinants . - answerFalse
5. In multicellular organisms , different cells have different functions though they still
have the same whole genome . How does that work ?
a . Differential gene expression
b . The genes are all in operons
c . The genes are linked in different ways
d . In different cells the codon are altered to prevent incorrect protein creation - answera
. Differential gene expression
6. Based on the following mature mRNAs after splicing has taken place , which exons
are constitutive ? ( numbers represent exons ) 1. 1-2-3-7-9-10 II . 1-2-4-5-6-7-9 III . 1-4-
5-8-9-10 . IV . 1-2-4-9-10
a . 1 and 7
b . 2 and 7
c . 1 and 9
d . 1 and 2 - answer?
7. ( T / F ) The first and last exons of a gene are always expressed in a functional
protein . - answer?
8. What is the function of the TATA box ?
a . The TATA box is a signal for transcription termination
, b . The TATA box binds TFIID
c . The TATA box binds to Mediator
d . TATA directs the spliceosome to the correct splice sites - answerb . The TATA box
binds TFIID
9. lacl codes for a protein that controls the lac operon and therefore it is constitutively
expressed . This means that lacl is
a . Directly attached to the lac operon
b . Always turned on and expressed
c . Only controlled through translational control - answer?
10. What is a reporter gene ?
a . A gene that is regulated by a reporter sequence
b . A gene that encodes a reporter enhancer
c . A regulatory sequence that controls a fluorescent protein or other visual marker
d . A gene that is used to investigate promoter activity - answer?
11. An operon is....
A. A regulatory unit consisting of a few structural genes under control of one promoter
B. A protein that binds to a specific DNA sequence to regulate certain genes a specific
time
C. A molecular contruct that has the coding region of some gene whose product is
easily assayed - answer?
Which of the following are not components of the preinitiation complex?
A. General trasncription factors
B. RNA polymerase
C. Sequence specific transcription factors
D. TFIID - answer?
The proteins that modulates the ability of splicosome to recognize or choose splice
sites.
A. Transcription factors
B. Splicing factors
C. RNAi
D. 5' UTR - answer?
Which of the following statements about transcription and translation is not true?
A. Translation in bacteria begins before mRNA transcription is completed
B. rRNA is involved in translation
C. Transcription regulation is not commonly used to control gene expression
D. mRNA is transported out of the nucleus in eukaryotes - answer?
If AUG codes for methionine, which of the following isoleucine codons is least likely to
be used?
a. AUU
1. Which of the following defines the principle of genetic linkage
a . Two or more genes that are physically connected on a chromosome
b . Genes that are transmitted to the next generation as a group RES
c . The process by which genetic information is exchanged between homologous
chromosomes
d . Both A and B
e . All of the above – answer d . Both A and B
2. While mapping genes in Drosophila , you observe 35 recombinants among 437 total
offspring . What is the distance between these genes ?
a . 26 map units
c . 12 map units
b . 18 map units
d . 8 map units
3. Convert that number to centimorgans . - answer2. d . 8 map units
3. 8 cM
4. T / F the answer you obtained # 2 is an accurate hypothesis for the distance , no
other forces influence the number of recombinants . - answerFalse
5. In multicellular organisms , different cells have different functions though they still
have the same whole genome . How does that work ?
a . Differential gene expression
b . The genes are all in operons
c . The genes are linked in different ways
d . In different cells the codon are altered to prevent incorrect protein creation - answera
. Differential gene expression
6. Based on the following mature mRNAs after splicing has taken place , which exons
are constitutive ? ( numbers represent exons ) 1. 1-2-3-7-9-10 II . 1-2-4-5-6-7-9 III . 1-4-
5-8-9-10 . IV . 1-2-4-9-10
a . 1 and 7
b . 2 and 7
c . 1 and 9
d . 1 and 2 - answer?
7. ( T / F ) The first and last exons of a gene are always expressed in a functional
protein . - answer?
8. What is the function of the TATA box ?
a . The TATA box is a signal for transcription termination
, b . The TATA box binds TFIID
c . The TATA box binds to Mediator
d . TATA directs the spliceosome to the correct splice sites - answerb . The TATA box
binds TFIID
9. lacl codes for a protein that controls the lac operon and therefore it is constitutively
expressed . This means that lacl is
a . Directly attached to the lac operon
b . Always turned on and expressed
c . Only controlled through translational control - answer?
10. What is a reporter gene ?
a . A gene that is regulated by a reporter sequence
b . A gene that encodes a reporter enhancer
c . A regulatory sequence that controls a fluorescent protein or other visual marker
d . A gene that is used to investigate promoter activity - answer?
11. An operon is....
A. A regulatory unit consisting of a few structural genes under control of one promoter
B. A protein that binds to a specific DNA sequence to regulate certain genes a specific
time
C. A molecular contruct that has the coding region of some gene whose product is
easily assayed - answer?
Which of the following are not components of the preinitiation complex?
A. General trasncription factors
B. RNA polymerase
C. Sequence specific transcription factors
D. TFIID - answer?
The proteins that modulates the ability of splicosome to recognize or choose splice
sites.
A. Transcription factors
B. Splicing factors
C. RNAi
D. 5' UTR - answer?
Which of the following statements about transcription and translation is not true?
A. Translation in bacteria begins before mRNA transcription is completed
B. rRNA is involved in translation
C. Transcription regulation is not commonly used to control gene expression
D. mRNA is transported out of the nucleus in eukaryotes - answer?
If AUG codes for methionine, which of the following isoleucine codons is least likely to
be used?
a. AUU
