Genetics Essentials: Concepts and Connections 5th Edition by
h h h h h h h
Benjamin A. Pierce
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,TABLE OF CONTENT
h h
Chapterh01:hIntroductionhtohGenetics ........................................................................................................................ 3
Chapterh02:hChromosomeshandhCellularhReproduction........................................................................................... 15
Chapterh03:hBasichPrincipleshofhHeredity ................................................................................................................ 32
Chapterh04:hExtensionshandhModificationshofhBasichPrinciples .............................................................................. 59
Chapterh05:hLinkage,hRecombination,handhEukaryotichGenehMapping................................................................... 98
Chapterh06:hChromosomehVariation ..................................................................................................................... 115
Chapterh07:hBacterialhandhViralhGenetichSystems ................................................................................................. 139
Chapterh08hDNA:hThehChemicalhNaturehofhthehGene ............................................................................................ 152
Chapterh09:hDNAhReplicationhandhRecombination ............................................................................................... 181
Chapterh10:hFromhDNAhtohProteins:hTranscriptionhandhRNAhProcessing ............................................................. 198
Chapterh11:hFromhDNAhtohProteins:hTranslation .................................................................................................. 224
Chapterh12:hControlhofhGenehExpression .............................................................................................................. 244
Chapterh13:hGenehMutations,hTransposablehElements,handhDNAhRepair ............................................................. 278
Chapterh14:hMolecularhGenetichAnalysishandhBiotechnology ............................................................................... 298
Chapterh15:hGenomicshandhProteomics ................................................................................................................. 314
Chapterh16:hCancerhGenetics ................................................................................................................................ 332
Chapterh17:hQuantitativehGenetics ........................................................................................................................ 346
Chapterh18:hPopulationhandhEvolutionaryhGenetics .............................................................................................. 366
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,Chapterh01:hIntroductionhtohGenetics
1. Albinismhishrarehinhmosthhumanhpopulations,hoccurringhathahfrequencyhofhabouth1hinh20,000hpeople.hHowever,hth
ehtraithoccurshathahfrequencyhofh1hinh200hinhcertainhHopihvillageshofhBlackhMesahinhArizona.hExplainhinhtermshofhnat
uralhselectionhwhyhalbinismhishsohrarehinhmosthhumanhpopulations.
ANSWER:hInhmosthpopulations,htherehishfairlyhstronghselectionhagainsthalbinismhbecausehalbinoshdon’thproducehme
lanin,hcausinghtheirhskinhcellshnothtohbehprotectedhfromhthehdamagingheffectshofhsunlight.hAlso,hthehlackh
ofhmelaninhinhtheirheyeshcauseshthemhtohhavehpoorheyesight.hFinally,hinhmosthcultureshalbinosharehseenha
shabnormal,handhtheyharehnothnormallyhsoughthouthforhmarriagehandhmating.hTherefore,hinhmosthpopulat
ionshthehalleleshthathcausehalbinismharehselectedhagainst,handhtheyhdecreasehinhfrequencyhorharehkepthathah
lowhlevel,hcausinghthehrecessivehtraithtohbehrare.
2. Albinismhishrarehinhmosthhumanhpopulations,hoccurringhathahfrequencyhofhabouth1hinh20,000hpeople.hHowever,hth
ehtraithoccurshathahfrequencyhofh1hinh200hinhcertainhHopihvillageshofhBlackhMesahinhArizona.hExplainhinhtermshofhnat
uralhselectionhwhyhthehtraithishsohmuchhmorehcommonhamonghthehHopishofhBlackhMesa.
ANSWER:hAlbinoshoccupyhahprivilegedhpositionhamonghthehHopishofhBlackhMesa.hInhthishculture,halbinosharehv
iewedhashespeciallyhpretty,hclean,handhintelligent,handhtheyhoftenhoccupyhpositionshofhleadership.hAl
binosharehcelebratedhinhthehvillageshashahsignhofhpurityhofhHopihbloodhinhthehcommunity.
Furthermore,halbinosharehoftenhexcusedhfromhnormalhmalehfieldhlaborhbecausehofhtheirhsensitivityhtohsu
nlight,hcausinghthemhtohbehlefthbehindhinhthehvillagehwithhthehwomenhduringhthehdaytime.hThishallowsht
hemhextrahmatinghopportunitieshcomparedhtohthehotherhmenhofhthehvillage.hTherefore,hthehalleleshthathc
ausehalbinismhareheitherhselectedhforhinhthishculturehorhathleasthnothselectedhagainsthashstronglyhashinhoth
erhcultures,hallowinghthehtraithtohoccurhathahmuchhhigherhfrequency.
3. WhichhonehofhthehfollowinghpairingshbetweenhthehsubdisciplinehofhgeneticshandhthehphenomenonhishI
NCORRECT?
a. evolution—populationhgenetics
b. genehregulation—molecularhgenetics
c. allelichfrequencyhalteration—populationhgenetics
d. arrangementhofhgeneshonhchromosome—transmissionhgenetics
e. chemicalhnaturehofhthehgene—transmissionhgenetics
ANSWER:he
4. Whichhonehofhthehfollowinghtopicshofhresearchhbelongshtohthehdisciplinehofhtransmissionhgenetics?
a. inheritancehpatternhofhgenehalleles
b. mechanismhofhDNAhreplication
c. genehexpressionhpatterns
d. evolution
e. chemicalhmodificationhofhnucleichacids
ANSWER:ha
5. Thehcompletehgenetichmakeuphofhanhorganismhishreferredhtohashits
a. chromosome.
b. alleles.
c. locus.
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, d. genome.
e. phenotype.
ANSWER:hd
6. IdentifyhahTRUEhstatementhfromhthehfollowinghdescriptionshconcerninghgenetics.
a. Thehtheoryhofhpangenesishstateshthathallhlivinghorganismsharehcomposedhofhcells.
b. Bacteriahandhvirusesharehnothusefulhinhstudyinghgeneshandhinheritancehbecausehtheyharehstructurallyha
ndhmetabolicallyhdifferenthfromheukaryotichcells.
c. CharleshDarwinhaccuratelyhdescribedhthehlawshofhinheritancehinhhishlandmarkhbook,hOnhthehOriginhofhS
pecies.
d. Manyhhumanhtraits,hsuchhashskinhandhhairhcolor,harehdeterminedhbyhmorehthanhahsinglehgene.
e. Evolutionhcanhoccurhwithouthgenetichchangeshinhthehpopulation.
ANSWER:hd
7. IdentifyhahFALSEhstatementhfromhthehfollowinghdescriptionshofhgenetics.
a. Humanshfirsthappliedhgeneticshtohthehdomesticationhofhplantshandhanimalshbetweenhapproximatelyh1
0,000handh12,000hyearshago.
b. SomehviruseshusehRNAhtohcarryhtheirhgenetichinformation.
c. Albinismhresultshfromhahmutationhinhthehgeneshthathcontrolhthehsynthesishandhstoragehofhmelanin.
d. Allhhumanhtraitshthathdisplayhblendinghinheritanceharehaffectedhbyhahsinglehgene.
e. Thehprocesshbyhwhichhgenetichinformationhishcopiedhandhdecodedhishsimilarhforhallhformshofhlife.
ANSWER:hd
8. Whichhofhthehfollowinghspecieshishconsideredhahmodelhgenetichorganism?
a. thehplanthLinariahvulgaris
b. thehdeerhmousehPeromyscushmaniculatus
c. thehwormhCaenorhabditishelegans
d. thehfroghHylahchrysoscelis
e. thehchimpanzeehPanhtroglodytesh
ANSWER:hc
9. WhichhofhthehfollowinghwouldhservehthehLEASThwellhashahmodelhforhunderstandinghbasichmechanismshofhi
nheritance?
a. fruithflies
b. humans
c. yeast
d. mice
e. zebrafish
ANSWER:hb
10. WhichhofhthehfollowinghstatementshishTRUE?
a. Eachhsubdisciplinehofhgeneticshishveryhspecifichashtohwhathishexploredhandhdoeshnothoverlaphwithhthe
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