BIO 251 EXAM 2 COMPREHENSIVE
ASSESSMENT
Compartmentalized (biceps/triceps etc)
Run from end to end
Large cells - answer ✔✔-Skeletal Muscle Cell properties [11]
Thick/Thin myofilaments (do NOT shorten)
Sarcomers
Myofibrils
Skeletal Muscle Cell - answer ✔✔-Organization of Skeletal Muscle [11]
(a.k.a) Myosin
2 identical subunits
head sits on a "hinge"
Binding sites for ATPase & Actin
1/2 go each direction - answer ✔✔-Thick Filaments of Skeletal [11]
-Actin- binding site for myosin
-Tropomyosin- overlaps actin/myosin binding sites
-Troponin- 3 binding sites, attached at intervals to actin/tropomyosin - answer ✔✔-Thin Filaments of
Skeletal (helix configuration)
Regulatory protein, part of excitation-contraction coupling
3 Binding sites:
-Actin
-Tropomyosin
-Reversibly binds to Ca++ - answer ✔✔-Troponin [11]
Highly organized
1. Protein Z-disk
2.Thin- attach to Z-disk
Thick- venter of sarcomere (connected by protein Titin - answer ✔✔-Sarcomeres [11]
A & I Bands
Causes alternating light & dark bands - answer ✔✔-Adjacent sarcomeres [11]
1.Myosin heads attach to actin (cross-bridge forms)
2."Power Stroke"= Head rotate & pull THIN along THICK towards center of sarcomere
3.Release & re-cock & repeat
-(Z-disks are pulled together)
-Requires ATP to myosin head before detachment - answer ✔✔-Cross-Bridge Cycle [11]
muscle stiffness after death
-no new ATP & cross-bridges remain contracted - answer ✔✔-Rigor Motis [11]
1. Phosphorylation of ADP by Creatine Phosphate
2. Oxidative phosphorylation of ADP in mitochondria
3. Anaerobic Glycolysis - answer ✔✔-Sources of ATP in skeletal muslce [11]
1st source of ATP
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ASSESSMENT
Compartmentalized (biceps/triceps etc)
Run from end to end
Large cells - answer ✔✔-Skeletal Muscle Cell properties [11]
Thick/Thin myofilaments (do NOT shorten)
Sarcomers
Myofibrils
Skeletal Muscle Cell - answer ✔✔-Organization of Skeletal Muscle [11]
(a.k.a) Myosin
2 identical subunits
head sits on a "hinge"
Binding sites for ATPase & Actin
1/2 go each direction - answer ✔✔-Thick Filaments of Skeletal [11]
-Actin- binding site for myosin
-Tropomyosin- overlaps actin/myosin binding sites
-Troponin- 3 binding sites, attached at intervals to actin/tropomyosin - answer ✔✔-Thin Filaments of
Skeletal (helix configuration)
Regulatory protein, part of excitation-contraction coupling
3 Binding sites:
-Actin
-Tropomyosin
-Reversibly binds to Ca++ - answer ✔✔-Troponin [11]
Highly organized
1. Protein Z-disk
2.Thin- attach to Z-disk
Thick- venter of sarcomere (connected by protein Titin - answer ✔✔-Sarcomeres [11]
A & I Bands
Causes alternating light & dark bands - answer ✔✔-Adjacent sarcomeres [11]
1.Myosin heads attach to actin (cross-bridge forms)
2."Power Stroke"= Head rotate & pull THIN along THICK towards center of sarcomere
3.Release & re-cock & repeat
-(Z-disks are pulled together)
-Requires ATP to myosin head before detachment - answer ✔✔-Cross-Bridge Cycle [11]
muscle stiffness after death
-no new ATP & cross-bridges remain contracted - answer ✔✔-Rigor Motis [11]
1. Phosphorylation of ADP by Creatine Phosphate
2. Oxidative phosphorylation of ADP in mitochondria
3. Anaerobic Glycolysis - answer ✔✔-Sources of ATP in skeletal muslce [11]
1st source of ATP
GRADESMORE.COM
