Biology 200 Pre-Reading Quizzes Q&A
Is also known as the protein sequence. - ANSWER-primary structure
Results from covalent and non-covalent interactions between different polypeptide
chains - ANSWER-Quaternary structure
Results from non-covalent interactions between the R-groups - ANSWER-both
tertiary and quaternary
Peptide-bonded backbone of a polypeptide has the following key characteristics:
Select all that apply. - ANSWER-The R-groups (side chains) project out from the
backbone such that they may interact with each other.
The structure is flexible due to single bonds on either side of the peptide bonds in the
backbone.
The backbone has an amino group on one end and a carboxyl group on the other
end thus providing directionality.
Membrane lipids are capable of many different types of movement. Which of these
does not occur spontaneously in biological membranes? - ANSWER-switching
between leaflets of the bilayer
In an experiment with fluorescently labeled lipids, a bleached area of membrane
gradually regains fluorescence because of: - ANSWER-Lateral diffusion of non-
bleached lipids into the bleached area
Membrane synthesis in the cell requires the regulation of growth for both halves of
the bilayer and the selective retention of certain types of lipids on one side or the
other. Which group of enzymes accomplishes both of these tasks? - ANSWER-
Flippases
New membrane phospholipids are synthesized by enzymes bound to the
________________ side of the ___________________ membrane. Note that you
must get the spelling right for your answer to be accepted. - ANSWER-Cytosolic
Endoplasmic Reticulum
A region of a protein that forms a functional component of a protein is called a(n): -
ANSWER-Domain
The side chains of the amino acids within the transmembrane portion of a membrane
protein will typically be: (select all that apply) - ANSWER-Hydrophobic
Non Polar
, Membrane proteins, like membrane lipids, can move laterally by exchanging
positions with other membrane components. Which type of membrane proteins is
expected to be the least mobile, based on their function? - ANSWER-anchors
Which of the following is NOT an integral membrane protein? - ANSWER-A protein
attached to the membrane by non-covalent interactions with other membrane
proteins
Which of the following DNA strands can form a DNA duplex by pairing with itself at
each position in an anti-parallel fashion? - ANSWER-5'-AAGCGCTT-3'
Choose all that apply: The design of the nuclear envelope is such that... -
ANSWER-...its perinuclear space is continuous with the ER lumen.
Correct! ...the outer nuclear envelope have ribosomes bound to it.
...it is a double membrane.
...its outer membrane is continuous with the ER.
...the nuclear pores dispersed through out the envelope connect the cytoplasm with
the nucleoplasm.
...the chromatin is able to attach to the inner envelope at discrete regions.
...the inner membrane is in direct contact with the nuclear lamina.
Transport in and out of the nucleus of molecules larger than 9 nm ... - ANSWER-
must have a nuclear localization sequence (NLS) for entry into the nucleus, that is
NOT removed after entry.
requires a nuclear import receptor protein in the cytoplasm to recognize the NLS and
bring it to the nuclear pore for entry into the nucleus.
requires energy in the form of GTP.
is an active transport process.
The NLS (nuclear localization signal/ sequence) ... - ANSWER-is recognized by a
soluble nuclear import receptor protein in the cytoplasm and taken to the nuclear
pore complexes, for entry into the nucleus.
is a short stretch of amino acyl residues in the protein destined to the nucleus.
is not the signal sequence for transport out of the nucleus.
has a consensus basic amino acid residue sequence, KKKRK.
The nuclear lamina... - ANSWER-is a meshwork of intermediate filament proteins
called the lamins.
has a structural role in providing support to the nuclear envelope.
breakdown can cause the breakdown of the nuclear envelope during mitosis.
breakdown is caused by the phosphorylation of lamin proteins.
The nucleolus ... - ANSWER-is an area in the nucleus containing expanded
chromosomal loops of rDNA from different chromosomes.
is an area of intense rRNA transcription activity.
Is a region of collected DNA segments that must be diassembled in order for mitosis
to occur.
Histones are said to belong to a family of basic proteins, because they are rich in: -
ANSWER-basic amino acyl residues carrying an overall positive charge.
Is also known as the protein sequence. - ANSWER-primary structure
Results from covalent and non-covalent interactions between different polypeptide
chains - ANSWER-Quaternary structure
Results from non-covalent interactions between the R-groups - ANSWER-both
tertiary and quaternary
Peptide-bonded backbone of a polypeptide has the following key characteristics:
Select all that apply. - ANSWER-The R-groups (side chains) project out from the
backbone such that they may interact with each other.
The structure is flexible due to single bonds on either side of the peptide bonds in the
backbone.
The backbone has an amino group on one end and a carboxyl group on the other
end thus providing directionality.
Membrane lipids are capable of many different types of movement. Which of these
does not occur spontaneously in biological membranes? - ANSWER-switching
between leaflets of the bilayer
In an experiment with fluorescently labeled lipids, a bleached area of membrane
gradually regains fluorescence because of: - ANSWER-Lateral diffusion of non-
bleached lipids into the bleached area
Membrane synthesis in the cell requires the regulation of growth for both halves of
the bilayer and the selective retention of certain types of lipids on one side or the
other. Which group of enzymes accomplishes both of these tasks? - ANSWER-
Flippases
New membrane phospholipids are synthesized by enzymes bound to the
________________ side of the ___________________ membrane. Note that you
must get the spelling right for your answer to be accepted. - ANSWER-Cytosolic
Endoplasmic Reticulum
A region of a protein that forms a functional component of a protein is called a(n): -
ANSWER-Domain
The side chains of the amino acids within the transmembrane portion of a membrane
protein will typically be: (select all that apply) - ANSWER-Hydrophobic
Non Polar
, Membrane proteins, like membrane lipids, can move laterally by exchanging
positions with other membrane components. Which type of membrane proteins is
expected to be the least mobile, based on their function? - ANSWER-anchors
Which of the following is NOT an integral membrane protein? - ANSWER-A protein
attached to the membrane by non-covalent interactions with other membrane
proteins
Which of the following DNA strands can form a DNA duplex by pairing with itself at
each position in an anti-parallel fashion? - ANSWER-5'-AAGCGCTT-3'
Choose all that apply: The design of the nuclear envelope is such that... -
ANSWER-...its perinuclear space is continuous with the ER lumen.
Correct! ...the outer nuclear envelope have ribosomes bound to it.
...it is a double membrane.
...its outer membrane is continuous with the ER.
...the nuclear pores dispersed through out the envelope connect the cytoplasm with
the nucleoplasm.
...the chromatin is able to attach to the inner envelope at discrete regions.
...the inner membrane is in direct contact with the nuclear lamina.
Transport in and out of the nucleus of molecules larger than 9 nm ... - ANSWER-
must have a nuclear localization sequence (NLS) for entry into the nucleus, that is
NOT removed after entry.
requires a nuclear import receptor protein in the cytoplasm to recognize the NLS and
bring it to the nuclear pore for entry into the nucleus.
requires energy in the form of GTP.
is an active transport process.
The NLS (nuclear localization signal/ sequence) ... - ANSWER-is recognized by a
soluble nuclear import receptor protein in the cytoplasm and taken to the nuclear
pore complexes, for entry into the nucleus.
is a short stretch of amino acyl residues in the protein destined to the nucleus.
is not the signal sequence for transport out of the nucleus.
has a consensus basic amino acid residue sequence, KKKRK.
The nuclear lamina... - ANSWER-is a meshwork of intermediate filament proteins
called the lamins.
has a structural role in providing support to the nuclear envelope.
breakdown can cause the breakdown of the nuclear envelope during mitosis.
breakdown is caused by the phosphorylation of lamin proteins.
The nucleolus ... - ANSWER-is an area in the nucleus containing expanded
chromosomal loops of rDNA from different chromosomes.
is an area of intense rRNA transcription activity.
Is a region of collected DNA segments that must be diassembled in order for mitosis
to occur.
Histones are said to belong to a family of basic proteins, because they are rich in: -
ANSWER-basic amino acyl residues carrying an overall positive charge.
