Chemotherapy consenting is to be performed by the patient's ______________________. -
Correct Answer attending physician
When is a new chemo consent required? - Correct Answer When the drug is used in a new
way, or if a new drug is added to the regimen.
A UPMC fellow cannot write orders independently in the __________. - Correct Answer first
three months
Vesicant IVP chemo rate - Correct Answer 5 ml/min
When vesicant chemo is administered via IVP, check blood return every ______ mls. - Correct
Answer 3-5
Are alkylating agents cell cycle specific or non-cell cycle specific? - Correct Answer Non-specific
What kind of tumors are alkylating agents used for? - Correct Answer Large, slow-growing
Alkylating agent toxicities - Correct Answer -N/V
-Myelosuppression
-Infertility
-Hyposensitivity
-Alopecia
-Secondary malignancies
-TLS
-Teratogenic D
, This type of alkylating agents cross the blood brain barrier. - Correct Answer Nitrosoureas
Examples of nitrosoureas: - Correct Answer Carmustine, lomustine
Side effect of carmustine infusion - Correct Answer Intoxicated feeling
Example of ethylnimines - Correct Answer Thiotepa
Example of alkyl sulfonates - Correct Answer Busulfan
Calvert formula - Correct Answer AUC x (GFR + 25)
Temozolamine (Temodar) may have neurological effects because __________________. -
Correct Answer it crosses the blood brain barrier.
__________________ should always be mixed with D5W. - Correct Answer Oxaliplatin
Late complication of busulfan - Correct Answer Pulmonary fibrosis
Example of platinum agents - Correct Answer Carboplatin, cisplatin, oxaliplatin
Example of vinca alkaloids - Correct Answer Vincristine, vinblastine
This alkylating agent is more likely to cause nausea and vomiting - Correct Answer Cisplatin
(Platinol)