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They combat the extrapyramidal side effects of the neuroleptic drug. - (ANSWER)A nurse is
administering medications to clients on a psychiatric unit. What does the nurse identify as the reason
that so many psychiatric clients are given the drug benztropine or trihexyphenidyl in conjunction with
the phenothiazine-derivative neuroleptic medications?
Torticollis - (ANSWER)acute dystonia that involves muscle spasms of the neck; develops within 1 to 5
days after beginning therapy with a conventional antipsychotic
Tardive dyskinesia - (ANSWER)involuntary repetitious tonic muscular spasms that involve the face,
tongue, lips, limbs, and trunk; takes several months to years to develop after the start of therapy with a
conventional antipsychotic
d/c if observed, may be reversible
Pseudoparkinsonism - (ANSWER)extrapyramidal tract response that includes masklike facies, shuffling
gait, pill-rolling tremors, stooped posture, and drooling; develops within several days to 1 month after
the start of therapy with a conventional antipsychotic
Neuroleptic malignant syndrome - (ANSWER)severe, potentially fatal response to conventional
antipsychotics
caused by acute reduction in dopamine activity, precipitating hyperthermia/pyrexia, tachycardia,
tachypnea, unstable blood pressure, dyskinesia, incontinence, decreased level of consciousness
Clozapine - (ANSWER)2nd gen atypical antipsychotic drug that is more effective than other second-
generation antipsychotics
Seizures, sedation, and akathisia are common side effects
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contraindicated in clients with bone marrow depression
may cause agranulocytosis, the client's white blood cell (WBC) count should be monitored weekly. The
drug should be discontinued if the count falls below 3,000/mm 3
use with caution in clients with seizures
Isocarboxazid - (ANSWER)MAOI
Circulatory collapse is associated with toxicity
fluphenazine - (ANSWER)typical antipsychotic
Acute dystonic reactions such as tremors, dyskinesia, and akathisia are observable side effects
decreased salivating
haloperidol - (ANSWER)antipsychotic drug used in the long-term treatment of psychosis
Gynecomastia is one of the adverse effects of this drug
Potential adverse effects: pseudoparkinsonism and urinary retention related to extrapyramidal
syndrome
Ziprasidone - (ANSWER)atypical antipsychotic