NR 568 Week 8 Final Exam 2025|
Chamberlain University| Actual Exam
Questions and Correct Answers
Question 1: How does hormone therapy aid osteoporosis?
A. By increasing bone resorption
B. By decreasing estrogen levels
C. By preventing bone loss and reducing fracture risk
D. By promoting calcium excretion
Correct answer: C
Explanation: Hormone therapy replaces declining estrogen, which inhibits osteoclast activity,
slows bone resorption, increases bone mineral density, and reduces the risk of fractures in
postmenopausal women.
Question 2: When should progestin be used for hormone replacement therapy?
A. In women without a uterus
B. In women with an intact uterus
C. Only in premenopausal women
D. In all menopausal women regardless of uterine status
Correct answer: B
Explanation: Progestin is added to estrogen in HRT for women with a uterus to prevent
endometrial hyperplasia and reduce the risk of adenocarcinoma.
Question 3: When should progestin NOT be used for hormone replacement therapy?
A. In women with an intact uterus
B. In women without a uterus (post-hysterectomy)
C. In women with comorbidities
D. In all cases of HRT
,Correct answer: B
Explanation: Progestin is not necessary in women without a uterus, as there is no endometrium
to protect from hyperplasia.
Question 4: When should local estrogen be used?
A. For systemic symptoms like hot flashes
B. For vaginal atrophy, dryness, and urinary symptoms
C. For osteoporosis prevention
D. For mood stabilization
Correct answer: B
Explanation: Local estrogen therapy is indicated for genitourinary symptoms of menopause,
such as vaginal dryness and irritation, with minimal systemic effects.
Question 5: When should systemic estrogen be used?
A. Exclusively for vaginal symptoms
B. For hot flashes, night sweats, and osteoporosis prevention
C. In pregnant women
D. For male hypogonadism
Correct answer: B
Explanation: Systemic estrogen is recommended for vasomotor symptoms and bone protection
in menopausal women when initiated appropriately.
Question 6: What is the purpose of peri-menopausal estrogen therapy?
A. To accelerate menopause
B. To relieve hot flashes, vaginal dryness, and other symptoms
C. To prevent conception
D. To treat hypertension
Correct answer: B
Explanation: Peri-menopausal estrogen therapy aims to manage transitional symptoms like
vasomotor instability and genitourinary changes by replacing declining hormones.
, Question 7: Which form of estrogen therapy has fewer ADR?
A. Oral estrogen
B. Transdermal estrogen
C. Intramuscular estrogen
D. Vaginal estrogen for systemic use
Correct answer: B
Explanation: Transdermal estrogen has fewer adverse effects, such as lower risk of venous
thromboembolism, compared to oral forms due to bypassing hepatic first-pass metabolism.
Question 8: What medication is used for osteoporosis, osteopenia, and HRT?
A. Bisphosphonates
B. Estrogen
C. Parathyroid hormone
D. Denosumab
Correct answer: B
Explanation: Estrogen in HRT is approved for preventing osteoporosis in postmenopausal
women and can treat osteopenia by maintaining bone density.
Question 9: How to change pt from one OC to another?
A. Stop old OC and wait 7 days before starting new
B. Switch immediately without a gap
C. Overlap both for 14 days
D. Discontinue all OCs permanently
Correct answer: B
Explanation: Transition directly from one OC to another without a gap to maintain
contraceptive efficacy and avoid breakthrough bleeding or ovulation.
Question 10: When is the best time in cycle to start new OC?
Chamberlain University| Actual Exam
Questions and Correct Answers
Question 1: How does hormone therapy aid osteoporosis?
A. By increasing bone resorption
B. By decreasing estrogen levels
C. By preventing bone loss and reducing fracture risk
D. By promoting calcium excretion
Correct answer: C
Explanation: Hormone therapy replaces declining estrogen, which inhibits osteoclast activity,
slows bone resorption, increases bone mineral density, and reduces the risk of fractures in
postmenopausal women.
Question 2: When should progestin be used for hormone replacement therapy?
A. In women without a uterus
B. In women with an intact uterus
C. Only in premenopausal women
D. In all menopausal women regardless of uterine status
Correct answer: B
Explanation: Progestin is added to estrogen in HRT for women with a uterus to prevent
endometrial hyperplasia and reduce the risk of adenocarcinoma.
Question 3: When should progestin NOT be used for hormone replacement therapy?
A. In women with an intact uterus
B. In women without a uterus (post-hysterectomy)
C. In women with comorbidities
D. In all cases of HRT
,Correct answer: B
Explanation: Progestin is not necessary in women without a uterus, as there is no endometrium
to protect from hyperplasia.
Question 4: When should local estrogen be used?
A. For systemic symptoms like hot flashes
B. For vaginal atrophy, dryness, and urinary symptoms
C. For osteoporosis prevention
D. For mood stabilization
Correct answer: B
Explanation: Local estrogen therapy is indicated for genitourinary symptoms of menopause,
such as vaginal dryness and irritation, with minimal systemic effects.
Question 5: When should systemic estrogen be used?
A. Exclusively for vaginal symptoms
B. For hot flashes, night sweats, and osteoporosis prevention
C. In pregnant women
D. For male hypogonadism
Correct answer: B
Explanation: Systemic estrogen is recommended for vasomotor symptoms and bone protection
in menopausal women when initiated appropriately.
Question 6: What is the purpose of peri-menopausal estrogen therapy?
A. To accelerate menopause
B. To relieve hot flashes, vaginal dryness, and other symptoms
C. To prevent conception
D. To treat hypertension
Correct answer: B
Explanation: Peri-menopausal estrogen therapy aims to manage transitional symptoms like
vasomotor instability and genitourinary changes by replacing declining hormones.
, Question 7: Which form of estrogen therapy has fewer ADR?
A. Oral estrogen
B. Transdermal estrogen
C. Intramuscular estrogen
D. Vaginal estrogen for systemic use
Correct answer: B
Explanation: Transdermal estrogen has fewer adverse effects, such as lower risk of venous
thromboembolism, compared to oral forms due to bypassing hepatic first-pass metabolism.
Question 8: What medication is used for osteoporosis, osteopenia, and HRT?
A. Bisphosphonates
B. Estrogen
C. Parathyroid hormone
D. Denosumab
Correct answer: B
Explanation: Estrogen in HRT is approved for preventing osteoporosis in postmenopausal
women and can treat osteopenia by maintaining bone density.
Question 9: How to change pt from one OC to another?
A. Stop old OC and wait 7 days before starting new
B. Switch immediately without a gap
C. Overlap both for 14 days
D. Discontinue all OCs permanently
Correct answer: B
Explanation: Transition directly from one OC to another without a gap to maintain
contraceptive efficacy and avoid breakthrough bleeding or ovulation.
Question 10: When is the best time in cycle to start new OC?
