10/1/25, 12:22 AM [LAB MED] WEEK 2: Liver Disease
[LAB MED] WEEK 2: Liver Disease COMPREHENSIVE QUESTIONS
AND VERIFIED DETAILED SOLUTIONS |COMPLETE
SOLUTIONS |A+ GRADED |100% CORRECT!! LATEST
VERSION 2025-2026
Terms in this set (24)
- weighs 1 kg
- 2 blood inputs and 1 output
- 2 lobes
- can regrow
liver anatomy
- has hepatic artery and portal vein and blood supply
mix and go towards the center central vein
- bile caniliculi drain back into the duodenum from in to outside
bile ducts
- endothelial cells line the sinusoidal space
- hepatocytes are under the endothelial cells
- kupffer cells are tissue macrophages
- stelae cells respond to liver damage by forming scar tissue
liver architecture
- blood vessels are the portal vein and hepatic arteries
into central vein and vena cava
- billiard tree go to gall bladder and then intestines
- oxygen deprivation / hypoxia
- physical radiation or trauma
- chemicals such as pharmaceuticals toxins etc
- infectious agents viral
- immunological reactions
causes of liver disease
- genetic derangements
- nutritional imbalance
- hepatitis is inflammation of liver cells
- can be caused by Epstein Barr virus
/ 1/9
, 10/1/25, 12:22 AM [LAB MED] WEEK 2: Liver Disease
- reversible injury is accumulation of fat / steatosis or bilirubin
- inflammation due to changes in environment (cells swell and
leak)
liver injury - irreversible injury is necrosis or apoptosis
(hepatitis is formation of apoptotic bodies)
- chronic injury and inflammation leads to cirrhosis scarring
- this can be reduced if the injury is resolved but is all happening
at the same time
- gross appearance changes very little and appears
slightly mottled due to cell death
acute liver disease - can shrink slightly
- monocyte infiltrate but minimal inflammation
- cell death occurs due to apoptosis or necrosis
- gross appearance shows an enlarged liver with
cirrhotic nodules and colour or consistency changes
due to intracellular accumulation of fat
chronic liver disease
- significant inflammation and monocyte infiltration
- fibrosis and scarring
- fat accumulation and cellular swelling
- cell death
- common include viral hepatitis, or non viral
- non alcoholic fatty liver
- alcoholic fatty liver disease
- less common is autoimmune
- Wilsons disease
liver diseases
- haemochromatosis
- cholestasis (stop in flow of bile)
- consequences of portal hypertension, liver failure,
cirrhosis (no going back), jaundice
/ 2/9
[LAB MED] WEEK 2: Liver Disease COMPREHENSIVE QUESTIONS
AND VERIFIED DETAILED SOLUTIONS |COMPLETE
SOLUTIONS |A+ GRADED |100% CORRECT!! LATEST
VERSION 2025-2026
Terms in this set (24)
- weighs 1 kg
- 2 blood inputs and 1 output
- 2 lobes
- can regrow
liver anatomy
- has hepatic artery and portal vein and blood supply
mix and go towards the center central vein
- bile caniliculi drain back into the duodenum from in to outside
bile ducts
- endothelial cells line the sinusoidal space
- hepatocytes are under the endothelial cells
- kupffer cells are tissue macrophages
- stelae cells respond to liver damage by forming scar tissue
liver architecture
- blood vessels are the portal vein and hepatic arteries
into central vein and vena cava
- billiard tree go to gall bladder and then intestines
- oxygen deprivation / hypoxia
- physical radiation or trauma
- chemicals such as pharmaceuticals toxins etc
- infectious agents viral
- immunological reactions
causes of liver disease
- genetic derangements
- nutritional imbalance
- hepatitis is inflammation of liver cells
- can be caused by Epstein Barr virus
/ 1/9
, 10/1/25, 12:22 AM [LAB MED] WEEK 2: Liver Disease
- reversible injury is accumulation of fat / steatosis or bilirubin
- inflammation due to changes in environment (cells swell and
leak)
liver injury - irreversible injury is necrosis or apoptosis
(hepatitis is formation of apoptotic bodies)
- chronic injury and inflammation leads to cirrhosis scarring
- this can be reduced if the injury is resolved but is all happening
at the same time
- gross appearance changes very little and appears
slightly mottled due to cell death
acute liver disease - can shrink slightly
- monocyte infiltrate but minimal inflammation
- cell death occurs due to apoptosis or necrosis
- gross appearance shows an enlarged liver with
cirrhotic nodules and colour or consistency changes
due to intracellular accumulation of fat
chronic liver disease
- significant inflammation and monocyte infiltration
- fibrosis and scarring
- fat accumulation and cellular swelling
- cell death
- common include viral hepatitis, or non viral
- non alcoholic fatty liver
- alcoholic fatty liver disease
- less common is autoimmune
- Wilsons disease
liver diseases
- haemochromatosis
- cholestasis (stop in flow of bile)
- consequences of portal hypertension, liver failure,
cirrhosis (no going back), jaundice
/ 2/9
