Pager1rofr822
TEST BANK r
Katzung's Basic and Clinical Pharm
r r r r
acology, 16th Edition r r r
by Todd W. Vanderah, Chapters 1 - 66
r r r r r r r r
Katzung'srBasicrandrClinicalrPharmacology
, Pager2rofr822
rrrr
Table tx of tx Contents
rr rr rr rrrr rrrr rr rrrr
1. tx Introduction: tx The tx Nature tx of tx Drugs tx & tx Drug tx Development tx & tx Regulation
rr rr rrrr
2. tx Drug tx Receptors tx & tx Pharmacodynamics
rr rrrr rr rr rrrr rr rr rrrr rr
3. tx Pharmacokinetics tx & tx Pharmacodynamics: tx Rational tx Dosing tx & tx the tx Time tx Course tx of tx Drug tx Action
4.r txr Drugr txr Biotransformation
5.r txrPharmacogenomics
rr rrrr rr
6. tx Introduction tx to tx Autonomic tx Pharmacology
rr rrrr rr
7. tx Cholinoceptor-Activating tx & tx Cholinesterase-Inhibiting tx Drugs
rr rr
8. tx Cholinoceptor-Blocking tx Drugs
9.r txr Adrenoceptorrtxr Agonistsrtxr &rtxr Sympathomimeticr txr Drugs
10.rtxr Adrenoceptorr txr Antagonistr txr Drugs
rr rr
11. tx Antihypertensive tx Agents
rr rrrr rr rrrr rr
12. tx Vasodilators tx & tx the tx Treatment tx of tx Angina tx Pectoris
rr rr rrrr rr
13. tx Drugs tx Used tx in tx Heart tx Failure
14.rtxr Agentsrtxr Usedrtxr inr txr Cardiacrtxr Arrhythmias
15.rtxr Diureticr txr Agents
rr rr rrrr rr rr
16. tx Histamine, tx Serotonin, tx & tx the tx Ergot tx Alkaloids
rr rr
17. tx Vasoactive tx Peptides
rr rr rr rr rr rrrr rr
18. tx The tx Eicosanoids: tx Prostaglandins, tx Thromboxanes, tx Leukotrienes, tx & tx Related tx Compounds
19.rtxr Nitricr txr Oxide
20.rtxr Drugsr txr Usedr txr inrtxr Asthma
rr rrrr rr rrrr rr
21. tx Introduction tx to tx the tx Pharmacology tx of tx CNS tx Drugs
rr rr
22. tx Sedative-Hypnotic tx Drugs
rr rr
23. tx The tx Alcohols
24.rtxr Antiseizurer txr Drugs
25.rtxr Generalr txr Anesthetics
26.rtxr Localr txr Anesthetics
27.rtxr Skeletalr txr Muscler txr Relaxants
28.rtxrPharmacologicrtxr Managementr txrofrtxrParkinsonismr txr &r txr Otherrtxr Movementrtxr Disorders
29.rtxr Antipsychoticr txr Agentsr txr &rtxr Lithium
30.rtxr Antidepressantr txr Agents
31.rtxr Opioidrtxr Agonistsrtxr &rtxr Antagonists
32.rtxr Drugsr txrofrtxr Abuse
rr rr rrrr rr rr rr
33. tx Agents tx Used tx in tx Cytopenias; tx Hematopoietic tx Growth tx Factors
rr rr rrrr rrrr
34. tx Drugs tx Used tx in tx Disorders tx of tx Coagulation
35.rtxr Agentsrtxr Usedrtxr inr txr Dyslipidemia
36.rtxr Nonsteroidalrtxr Anti-Inflammatoryr txr Drugs,rtxr Disease-Modifyingr txr Antirheumaticr txr Drugs,rtxr Nonopioidrtxr Analgesics,r txr &rtxr Drugsr txr Usedr txrinrtxr Gout
37.rtxr Hypothalamicrtxr &rtxr Pituitaryrtxr Hormones
38.rtxr Thyroidr txr &rtxr Antithyroidr txr Drugs
39.rtxr Adrenocorticosteroidsrtxr &r txr Adrenocorticalr txr Antagonists
40.rtxr Ther txr Gonadalrtxr Hormonesrtxr&r txr Inhibitors
41.rtxrPancreaticrtxr Hormonesr txr &rtxr Antidiabeticrtxr Drugs
42.rtxr Agentsrtxr Thatr txr Affectr txr Boner txr Mineralrtxr Homeostasis
rr rrrr rr rr rrrr
43. tx Beta-Lactam tx & tx Other tx Cell tx Wall- tx & tx Membrane-Active tx Antibiotics rr
rr rr rr rr rr rrrr
44. tx Tetracyclines, tx Macrolides, tx Clindamycin, tx Chloramphenicol, tx Streptogramins, tx & tx Oxazolidinones
rr rrrr
45. tx Aminoglycosides tx & tx Spectinomycin
46.rtxr Sulfonamides,r txr Trimethoprim,rtxr &r txr Quinolones
47.rtxr Antimycobacterialrtxr Drugs
48.rtxr Antifungalrtxr Agents
49.rtxr Antiviralrtxr Agents
50.rtxrMiscellaneousrtxr Antimicrobialr txr Agents;rtxr Disinfectants,r txr Antiseptics,r txr &r txr Sterilants
51.rtxr Clinicalr txr Usertxrofrtxr Antimicrobialrtxr Agents
52.rtxr Antiprotozoalr txr Drugs
53.rtxr Clinicalr txrPharmacologyr txrofrtxrther txr Antihelminthicrtxr Drugs
54.rtxr Cancerrtxr Chemotherapy
55.rtxr Immunopharmacology
rr rrrr rr rrrr
56. tx Introduction tx to tx Toxicology: tx Occupational tx & tx Environmental
rr rr rr rrrr
57. tx Heavy tx Metal tx Intoxication tx & tx Chelators
rr rrrr rr rr
58. tx Management tx of tx the tx Poisoned tx Patient
rr rr rrrr rrrr rr
59. tx Special tx Aspects tx of tx Perinatal tx & tx Pediatric tx Pharmacology
rr rr rrrr rr
60. tx Special tx Aspects tx of tx Geriatric tx Pharmacology
61.rtxr Dermatologicr txrPharmacology
62.rtxr Drugsr txr Usedr txr inrtxrther txr Treatmentr txrofrtxr Gastrointestinalr txr Diseases
63.rtxr Therapeuticr txr &rtxr Toxicr txrPotentialr txrofr txr Over-the-Counterr txr Agents
64.rtxr Dietaryr txr Supplementsr txr &r txr Herbalr txr Medications
65.rtxr Rationalr txrPrescribingrtxr &r txrPrescriptionr txr Writing
66.rtxr Importantr txr Drugr txr Interactionsrtxr &r txr Theirr txr Mechanismsr txr
rrrr rr rr rrrr rrrr rr rrrr
Chapter tx 1. tx Introduction: tx The tx Nature tx of tx Drugs tx & tx Drug tx Development tx & tx Regulation
Katzung'srBasicrandrClinicalrPharmacology
, Pager3rofr822
1.
Arnurserworkingrinrradiologyradministersriodinertorarpatientrwhorisrhavingrarc
omputedrtomographyr(CT)rscan.rThernurserworkingronrtheroncologyrunitradmin
istersrchemotherapyrtorpatientsrwhorhavercancer.rAtrtherPublicrHealthrDepartme
nt,rarnurseradministersrarmeasles-mumps-rubellar(MMR)rvaccinertorar14-month-
oldrchildrasrarroutinerimmunization.rWhichrbranchrofrpharmacologyrbestrdescri
besrtheractionsrofrallrthreer nurses?
A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
ANSWER: B
Feedback:
Pharmacologyrisrtherstudyrofrtherbiologicreffectsrofrchemicals.rNursesrarerinvol
vedrwithrclinicalrpharmacologyrorrpharmacotherapeutics,rwhichrisrarbranchrofrp
harmacologyrthatrdealsrwithrtherusesrofrdrugsrtortreat,rprevent,randrdiagnoserdis
ease.rTherradiologyrnurserisradministeringrardrugrtorhelprdiagnoserardisease.rThe
roncologyrnurserisradministeringrardrugrtorhelprtreatrardisease.rPharmacoeconom
icsrincludesranyrcostsrinvolvedrinrdrugr therapy.
Pharmacodynamicsrinvolvesrhowrardrugraffectsrtherbodyrandrp
harmacokineticsrisrhowrtherbodyractsronrtherbody.
2.
Arphysicianrhasrorderedrintramuscularr(IM)rinjectionsrofrmorphine,rarnarcoti
c,reveryr4rhoursrasrneededrforrpainrinrarmotorrvehicleraccidentrvictim.rThernurser
israwarerthisrdrugrhasrarhighrabuserpotential.rUnderrwhatrcategoryrwouldrmorph
inerberclassified?
A) SchedulerI
B) SchedulerII
Katzung'srBasicrandrClinicalrPharmacology
, Pager4rofr822
C) SchedulerIII
D) SchedulerIV
ANSWER: B
Feedback:
NarcoticsrwithrarhighrabuserpotentialrarerclassifiedrasrSchedulerIIrdrugsrbecaus
erofrsevererdependencerliability.rSchedulerIrdrugsrhaverhighrabuserpotentialran
drnoracceptedrmedicalruse.rSchedulerIIIrdrugsrhaverarlesserrabuserpotentialrthan
rIIrandranracceptedrmedicalruse.rSchedulerIVrdrugsrhaverlowrabuserpotentialran
drlimitedrdependencer liability.
3.
WhenrinvolvedrinrphaserIIIrdrugrevaluationrstudies,rwhatrresponsibilitiesr
wouldrthernurserhave?
A) Workingrwithranimalsrwhorarergivenrexperimentalr drugs
B) Choosingrappropriaterpatientsrtorberinvolvedrinrtherdrugr study
C) Monitoringrandrobservingrpatientsrcloselyrforradverser effects
D) Conductingrresearchrtordeterminereffectivenessrofrther drug
ANSWER: C
Feedback:
PhaserIIIrstudiesrinvolveruserofrardrugrinrarvastrclinicalrpopulationrinrwhichrpati
entsrareraskedrtorrecordranyrsymptomsrtheyrexperiencerwhilertakingrtherdrugs.r
Nursesrmayrberresponsiblerforrhelpingrcollectrandranalyzertherinformationrtorb
ersharedrwithrtherFoodrandrDrugrAdministrationr(FDA)rbutrwouldrnotrconductr
researchrindependentlyrbecausernursesrdornotrprescribermedications.rUserofra
nimalsrinrdrugrtestingrisrdonerinrtherpreclinicalrtrials.rSelectrpatientsrwhorarerin
volvedrinrphaserIIrstudiesrtorparticipaterinrstudiesrwherertherparticipantsrhavert
herdiseasertherdrugrisrintendedrtortreat.rTheserpatientsrarermonitoredrcloselyrfo
rrdrugractionrandradversereffects.rPhaserIrstudiesrinvolverhealthyrhumanrvolun
teersrwhorarerusuallyrpaidrforrtheirrparticipation.rNursesrmayrobserverforradve
rsereffectsrandrtoxicity.
4.
Whatrconceptrisrconsideredrwhenrgenericrdrugsrarersubstitutedrforrbrandr
namerdrugs?
Katzung'srBasicrandrClinicalrPharmacology
TEST BANK r
Katzung's Basic and Clinical Pharm
r r r r
acology, 16th Edition r r r
by Todd W. Vanderah, Chapters 1 - 66
r r r r r r r r
Katzung'srBasicrandrClinicalrPharmacology
, Pager2rofr822
rrrr
Table tx of tx Contents
rr rr rr rrrr rrrr rr rrrr
1. tx Introduction: tx The tx Nature tx of tx Drugs tx & tx Drug tx Development tx & tx Regulation
rr rr rrrr
2. tx Drug tx Receptors tx & tx Pharmacodynamics
rr rrrr rr rr rrrr rr rr rrrr rr
3. tx Pharmacokinetics tx & tx Pharmacodynamics: tx Rational tx Dosing tx & tx the tx Time tx Course tx of tx Drug tx Action
4.r txr Drugr txr Biotransformation
5.r txrPharmacogenomics
rr rrrr rr
6. tx Introduction tx to tx Autonomic tx Pharmacology
rr rrrr rr
7. tx Cholinoceptor-Activating tx & tx Cholinesterase-Inhibiting tx Drugs
rr rr
8. tx Cholinoceptor-Blocking tx Drugs
9.r txr Adrenoceptorrtxr Agonistsrtxr &rtxr Sympathomimeticr txr Drugs
10.rtxr Adrenoceptorr txr Antagonistr txr Drugs
rr rr
11. tx Antihypertensive tx Agents
rr rrrr rr rrrr rr
12. tx Vasodilators tx & tx the tx Treatment tx of tx Angina tx Pectoris
rr rr rrrr rr
13. tx Drugs tx Used tx in tx Heart tx Failure
14.rtxr Agentsrtxr Usedrtxr inr txr Cardiacrtxr Arrhythmias
15.rtxr Diureticr txr Agents
rr rr rrrr rr rr
16. tx Histamine, tx Serotonin, tx & tx the tx Ergot tx Alkaloids
rr rr
17. tx Vasoactive tx Peptides
rr rr rr rr rr rrrr rr
18. tx The tx Eicosanoids: tx Prostaglandins, tx Thromboxanes, tx Leukotrienes, tx & tx Related tx Compounds
19.rtxr Nitricr txr Oxide
20.rtxr Drugsr txr Usedr txr inrtxr Asthma
rr rrrr rr rrrr rr
21. tx Introduction tx to tx the tx Pharmacology tx of tx CNS tx Drugs
rr rr
22. tx Sedative-Hypnotic tx Drugs
rr rr
23. tx The tx Alcohols
24.rtxr Antiseizurer txr Drugs
25.rtxr Generalr txr Anesthetics
26.rtxr Localr txr Anesthetics
27.rtxr Skeletalr txr Muscler txr Relaxants
28.rtxrPharmacologicrtxr Managementr txrofrtxrParkinsonismr txr &r txr Otherrtxr Movementrtxr Disorders
29.rtxr Antipsychoticr txr Agentsr txr &rtxr Lithium
30.rtxr Antidepressantr txr Agents
31.rtxr Opioidrtxr Agonistsrtxr &rtxr Antagonists
32.rtxr Drugsr txrofrtxr Abuse
rr rr rrrr rr rr rr
33. tx Agents tx Used tx in tx Cytopenias; tx Hematopoietic tx Growth tx Factors
rr rr rrrr rrrr
34. tx Drugs tx Used tx in tx Disorders tx of tx Coagulation
35.rtxr Agentsrtxr Usedrtxr inr txr Dyslipidemia
36.rtxr Nonsteroidalrtxr Anti-Inflammatoryr txr Drugs,rtxr Disease-Modifyingr txr Antirheumaticr txr Drugs,rtxr Nonopioidrtxr Analgesics,r txr &rtxr Drugsr txr Usedr txrinrtxr Gout
37.rtxr Hypothalamicrtxr &rtxr Pituitaryrtxr Hormones
38.rtxr Thyroidr txr &rtxr Antithyroidr txr Drugs
39.rtxr Adrenocorticosteroidsrtxr &r txr Adrenocorticalr txr Antagonists
40.rtxr Ther txr Gonadalrtxr Hormonesrtxr&r txr Inhibitors
41.rtxrPancreaticrtxr Hormonesr txr &rtxr Antidiabeticrtxr Drugs
42.rtxr Agentsrtxr Thatr txr Affectr txr Boner txr Mineralrtxr Homeostasis
rr rrrr rr rr rrrr
43. tx Beta-Lactam tx & tx Other tx Cell tx Wall- tx & tx Membrane-Active tx Antibiotics rr
rr rr rr rr rr rrrr
44. tx Tetracyclines, tx Macrolides, tx Clindamycin, tx Chloramphenicol, tx Streptogramins, tx & tx Oxazolidinones
rr rrrr
45. tx Aminoglycosides tx & tx Spectinomycin
46.rtxr Sulfonamides,r txr Trimethoprim,rtxr &r txr Quinolones
47.rtxr Antimycobacterialrtxr Drugs
48.rtxr Antifungalrtxr Agents
49.rtxr Antiviralrtxr Agents
50.rtxrMiscellaneousrtxr Antimicrobialr txr Agents;rtxr Disinfectants,r txr Antiseptics,r txr &r txr Sterilants
51.rtxr Clinicalr txr Usertxrofrtxr Antimicrobialrtxr Agents
52.rtxr Antiprotozoalr txr Drugs
53.rtxr Clinicalr txrPharmacologyr txrofrtxrther txr Antihelminthicrtxr Drugs
54.rtxr Cancerrtxr Chemotherapy
55.rtxr Immunopharmacology
rr rrrr rr rrrr
56. tx Introduction tx to tx Toxicology: tx Occupational tx & tx Environmental
rr rr rr rrrr
57. tx Heavy tx Metal tx Intoxication tx & tx Chelators
rr rrrr rr rr
58. tx Management tx of tx the tx Poisoned tx Patient
rr rr rrrr rrrr rr
59. tx Special tx Aspects tx of tx Perinatal tx & tx Pediatric tx Pharmacology
rr rr rrrr rr
60. tx Special tx Aspects tx of tx Geriatric tx Pharmacology
61.rtxr Dermatologicr txrPharmacology
62.rtxr Drugsr txr Usedr txr inrtxrther txr Treatmentr txrofrtxr Gastrointestinalr txr Diseases
63.rtxr Therapeuticr txr &rtxr Toxicr txrPotentialr txrofr txr Over-the-Counterr txr Agents
64.rtxr Dietaryr txr Supplementsr txr &r txr Herbalr txr Medications
65.rtxr Rationalr txrPrescribingrtxr &r txrPrescriptionr txr Writing
66.rtxr Importantr txr Drugr txr Interactionsrtxr &r txr Theirr txr Mechanismsr txr
rrrr rr rr rrrr rrrr rr rrrr
Chapter tx 1. tx Introduction: tx The tx Nature tx of tx Drugs tx & tx Drug tx Development tx & tx Regulation
Katzung'srBasicrandrClinicalrPharmacology
, Pager3rofr822
1.
Arnurserworkingrinrradiologyradministersriodinertorarpatientrwhorisrhavingrarc
omputedrtomographyr(CT)rscan.rThernurserworkingronrtheroncologyrunitradmin
istersrchemotherapyrtorpatientsrwhorhavercancer.rAtrtherPublicrHealthrDepartme
nt,rarnurseradministersrarmeasles-mumps-rubellar(MMR)rvaccinertorar14-month-
oldrchildrasrarroutinerimmunization.rWhichrbranchrofrpharmacologyrbestrdescri
besrtheractionsrofrallrthreer nurses?
A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
ANSWER: B
Feedback:
Pharmacologyrisrtherstudyrofrtherbiologicreffectsrofrchemicals.rNursesrarerinvol
vedrwithrclinicalrpharmacologyrorrpharmacotherapeutics,rwhichrisrarbranchrofrp
harmacologyrthatrdealsrwithrtherusesrofrdrugsrtortreat,rprevent,randrdiagnoserdis
ease.rTherradiologyrnurserisradministeringrardrugrtorhelprdiagnoserardisease.rThe
roncologyrnurserisradministeringrardrugrtorhelprtreatrardisease.rPharmacoeconom
icsrincludesranyrcostsrinvolvedrinrdrugr therapy.
Pharmacodynamicsrinvolvesrhowrardrugraffectsrtherbodyrandrp
harmacokineticsrisrhowrtherbodyractsronrtherbody.
2.
Arphysicianrhasrorderedrintramuscularr(IM)rinjectionsrofrmorphine,rarnarcoti
c,reveryr4rhoursrasrneededrforrpainrinrarmotorrvehicleraccidentrvictim.rThernurser
israwarerthisrdrugrhasrarhighrabuserpotential.rUnderrwhatrcategoryrwouldrmorph
inerberclassified?
A) SchedulerI
B) SchedulerII
Katzung'srBasicrandrClinicalrPharmacology
, Pager4rofr822
C) SchedulerIII
D) SchedulerIV
ANSWER: B
Feedback:
NarcoticsrwithrarhighrabuserpotentialrarerclassifiedrasrSchedulerIIrdrugsrbecaus
erofrsevererdependencerliability.rSchedulerIrdrugsrhaverhighrabuserpotentialran
drnoracceptedrmedicalruse.rSchedulerIIIrdrugsrhaverarlesserrabuserpotentialrthan
rIIrandranracceptedrmedicalruse.rSchedulerIVrdrugsrhaverlowrabuserpotentialran
drlimitedrdependencer liability.
3.
WhenrinvolvedrinrphaserIIIrdrugrevaluationrstudies,rwhatrresponsibilitiesr
wouldrthernurserhave?
A) Workingrwithranimalsrwhorarergivenrexperimentalr drugs
B) Choosingrappropriaterpatientsrtorberinvolvedrinrtherdrugr study
C) Monitoringrandrobservingrpatientsrcloselyrforradverser effects
D) Conductingrresearchrtordeterminereffectivenessrofrther drug
ANSWER: C
Feedback:
PhaserIIIrstudiesrinvolveruserofrardrugrinrarvastrclinicalrpopulationrinrwhichrpati
entsrareraskedrtorrecordranyrsymptomsrtheyrexperiencerwhilertakingrtherdrugs.r
Nursesrmayrberresponsiblerforrhelpingrcollectrandranalyzertherinformationrtorb
ersharedrwithrtherFoodrandrDrugrAdministrationr(FDA)rbutrwouldrnotrconductr
researchrindependentlyrbecausernursesrdornotrprescribermedications.rUserofra
nimalsrinrdrugrtestingrisrdonerinrtherpreclinicalrtrials.rSelectrpatientsrwhorarerin
volvedrinrphaserIIrstudiesrtorparticipaterinrstudiesrwherertherparticipantsrhavert
herdiseasertherdrugrisrintendedrtortreat.rTheserpatientsrarermonitoredrcloselyrfo
rrdrugractionrandradversereffects.rPhaserIrstudiesrinvolverhealthyrhumanrvolun
teersrwhorarerusuallyrpaidrforrtheirrparticipation.rNursesrmayrobserverforradve
rsereffectsrandrtoxicity.
4.
Whatrconceptrisrconsideredrwhenrgenericrdrugsrarersubstitutedrforrbrandr
namerdrugs?
Katzung'srBasicrandrClinicalrPharmacology
