NUR 529 Exam 2 Verified Multiple Choice and
Conceptual Actual Frequently Tested
Questions With Reviewed 100%
Correct Detailed Answers
Guaranteed Pass!!Current Update!!
Q1. What receptor does the SARS-CoV-2 (COVID-19) virus primarily bind to in
order to enter host cells?
A) DPP4 receptor
B) ACE2 receptor
C) TNF receptor
D) IL-6 receptor
Rationale: The spike (S) protein of SARS-CoV-2 has high affinity for the ACE2
receptor, allowing viral entry via endocytosis.
Q2. How does the COVID-19 virus enter the host cell after binding to ACE2?
A) Exocytosis
B) Direct membrane fusion
C) Endocytosis
D) Passive diffusion
Rationale: SARS-CoV-2 undergoes endocytosis after spike protein–ACE2 binding,
enabling viral RNA release into the cell.
Q3. What is a major consequence of reduced ACE2 receptors during COVID-19
infection?
A) Reduced nitric oxide
, B) Increased angiotensin II
C) Decreased hemoglobin
D) Increased surfactant production
Rationale: Loss of ACE2 receptors leads to unopposed angiotensin II activity,
promoting vasoconstriction, inflammation, and lung injury (ARDS).
Q4. In which of the following tissues is ACE2 expressed?
A) Lungs, kidneys, heart, intestines
B) Lungs only
C) Brain only
D) Muscles and tendons only
Rationale: ACE2 receptors are widely expressed in lungs, heart, kidneys,
intestines, liver, brain, and adipose tissue, explaining COVID’s multi-organ impact.
Q5. Which stage of COVID-19 progression is characterized by hypoxia, ground-
glass infiltrates, and ARDS?
A) Stage 1 – Asymptomatic
B) Stage 2 – Upper airway response
C) Stage 3 – Hypoxia/ARDS
D) Recovery phase
Rationale: Stage 3 involves severe disease, hypoxia, and progression to ARDS,
often requiring oxygen or mechanical ventilation.
Q6. Which of the following best describes the role of neutrophil dysfunction in
COVID-19?
A) Reduced neutrophil migration
B) Expansion of neutrophils and toxic NET formation
Conceptual Actual Frequently Tested
Questions With Reviewed 100%
Correct Detailed Answers
Guaranteed Pass!!Current Update!!
Q1. What receptor does the SARS-CoV-2 (COVID-19) virus primarily bind to in
order to enter host cells?
A) DPP4 receptor
B) ACE2 receptor
C) TNF receptor
D) IL-6 receptor
Rationale: The spike (S) protein of SARS-CoV-2 has high affinity for the ACE2
receptor, allowing viral entry via endocytosis.
Q2. How does the COVID-19 virus enter the host cell after binding to ACE2?
A) Exocytosis
B) Direct membrane fusion
C) Endocytosis
D) Passive diffusion
Rationale: SARS-CoV-2 undergoes endocytosis after spike protein–ACE2 binding,
enabling viral RNA release into the cell.
Q3. What is a major consequence of reduced ACE2 receptors during COVID-19
infection?
A) Reduced nitric oxide
, B) Increased angiotensin II
C) Decreased hemoglobin
D) Increased surfactant production
Rationale: Loss of ACE2 receptors leads to unopposed angiotensin II activity,
promoting vasoconstriction, inflammation, and lung injury (ARDS).
Q4. In which of the following tissues is ACE2 expressed?
A) Lungs, kidneys, heart, intestines
B) Lungs only
C) Brain only
D) Muscles and tendons only
Rationale: ACE2 receptors are widely expressed in lungs, heart, kidneys,
intestines, liver, brain, and adipose tissue, explaining COVID’s multi-organ impact.
Q5. Which stage of COVID-19 progression is characterized by hypoxia, ground-
glass infiltrates, and ARDS?
A) Stage 1 – Asymptomatic
B) Stage 2 – Upper airway response
C) Stage 3 – Hypoxia/ARDS
D) Recovery phase
Rationale: Stage 3 involves severe disease, hypoxia, and progression to ARDS,
often requiring oxygen or mechanical ventilation.
Q6. Which of the following best describes the role of neutrophil dysfunction in
COVID-19?
A) Reduced neutrophil migration
B) Expansion of neutrophils and toxic NET formation
