Nagelhout Questions and Answers (Nurse Anesthesia)
Fully Solved Practice Material (2025–2026)
Introduction:
This document contains fully solved exam questions and answers
based on Nagelhout’s Nurse Anesthesia textbook, updated for 2025–
2026. It covers essential anesthesia principles, including
pharmacology, MAC values, solubility coefficients, inhaled and IV
anesthetics, and clinical scenarios related to pediatrics, obstetrics,
cardiovascular, respiratory, and neurological considerations.
Additional study guide Q&As provide detailed explanations for
airway management, pharmacokinetics, anesthesia complications,
and patient-specific care strategies. This resource is designed for
exam preparation and mastery of key anesthesia concepts.
Exam Questions and Answers:
109. blocks autonomic response?--- correct answer --- What is the
MAC-bar?
110. 1.6 x higher?--- correct answer --- How much higher is MAC-
bar than MAC?
111. the dose?--- correct answer --- The MAC correlates to what?
112. speed?--- correct answer --- The BGPC correlates to what?
113. potency?--- correct answer --- The OGPC correlates to what?
114. The lower the blood/gas solubility coefficient, the faster the
rise of the anesthetic in the lungs?--- correct answer --- Principle
,regarding blood/gas solubility coeflcient and alveolar
concentration?
115. Nitrous oxide is faster than desflurane in spite of a higher
BGC due to the concentration effect. Nitrous is administered at 50-
70% versus desflurane at less than 10%?--- correct answer ---
What is true regarding nitrous vs desflurane speed?
116. Tells you how fast anesthetics go into the lungs (fraction of
alveoli/fraction inspired)?--- correct answer --- What is FA/FI
ratio?
117. the faster you breathe, the faster you go to sleep (reach a
higher alveolar concentration faster)?--- correct answer ---
Principle related to breathing and sleep speed?
118. the higher the dose, the faster it works?--- correct answer ---
Principle regarding concentration and speed of drug?
119. Your Fa goes up faster?--- correct answer --- If you increase
the % of a drug given, what happens?
120. Fast in, fast out?--- correct answer --- rule of thumb regarding
a low blood gas solubility?
121. slow in and out?--- correct answer --- rule of thumb regarding
a high solubility for blood/gas?
122. not; rapidly?--- correct answer --- An anesthetic with a low
blood/gas solubility is taken into the blood, therefore, the
alveolar/brain concentration rises
123. slows the delivery of all anesthetics?--- correct answer --- A
ventilation/perfusion deficit does what to all anesthetics?
,124. the fastest (lowest blood/gas coefficients)?--- correct answer
--- What type of anesthetics are attected the most by a V/Q deficit?
125. Go to sleep more slowly, the faster gases have a more
noticeably slower sleep time?--- correct answer --- What are two
characteristics of bad lungs and anesthetics?
126. 1.) Use a very low solubility agent (N20), along with another
agent with higher solubility
2.) Use high concentrations of the fast (low solubility) drug (N2O)?-
-- correct answer --- What are the two necessary components of the
second gas ettect?
127. with pneumothorax, bowel obstruction, inner ear surgery,
neurosurgical procedures with air injections, VAE, within 4 weeks
of a sulfar hexafluoride gas injection for ocular surgery,
laparoscopy, and in expansion of the ET tube cuff or PAC balloon?---
correct answer --- When can nitrous oxide gas expansion be bad?
128. turn it off?--- correct answer --- What should you do with
nitrous before closure during ENT cases?
129. N2O?--- correct answer --- Don't use what in a bowel
obstruction?
130. 10%?--- correct answer --- What percent of body mass are the
vessel-rich tissue (vital organs)?
131. 75% of CO?--- correct answer --- % perfusion the vessel-rich
tissues receive?
132. 4 L/min?--- correct answer --- How much flow do the vessel
rich tissues receive?
, 133. 50%?--- correct answer --- Percentage of body mass for
muscle?
134. 19% of CO?--- correct answer --- % perfusion for muscles?
135. 1 L/min?--- correct answer --- Flow of muscle tissue?
136. 20%?--- correct answer --- Percentage of fat in body mass?
137. 6% of CO?--- correct answer --- % perfusion of fat?
138. 0.4 L/min?--- correct answer --- Flow to fat?
139. 20%?--- correct answer --- Percentage of body mass for
vessel-poor tissue?
140. 0% of CO?--- correct answer --- perfusion of vessel-poor
tissue?
141. 0 L/min?--- correct answer --- Flow of vessel-poor tissue?
142. increases in cardiac output slow the onset of all anesthetics
(the highest blood gas agents are affected the most)?--- correct
answer --- Principle of cardiac output and anesthetics?
143. their onset will be slowed the most
(Will notice more of an effect on the slower gasses)?--- correct
answer --- How will higher BGC drugs be attected with tachycardia
and increased CO during induction?
144. it is faster?--- correct answer --- If heart rate and CO are low,
how is induction attected?
145. during emergence (waking up)?--- correct answer --- When
does dittusion hypoxia occur?
Fully Solved Practice Material (2025–2026)
Introduction:
This document contains fully solved exam questions and answers
based on Nagelhout’s Nurse Anesthesia textbook, updated for 2025–
2026. It covers essential anesthesia principles, including
pharmacology, MAC values, solubility coefficients, inhaled and IV
anesthetics, and clinical scenarios related to pediatrics, obstetrics,
cardiovascular, respiratory, and neurological considerations.
Additional study guide Q&As provide detailed explanations for
airway management, pharmacokinetics, anesthesia complications,
and patient-specific care strategies. This resource is designed for
exam preparation and mastery of key anesthesia concepts.
Exam Questions and Answers:
109. blocks autonomic response?--- correct answer --- What is the
MAC-bar?
110. 1.6 x higher?--- correct answer --- How much higher is MAC-
bar than MAC?
111. the dose?--- correct answer --- The MAC correlates to what?
112. speed?--- correct answer --- The BGPC correlates to what?
113. potency?--- correct answer --- The OGPC correlates to what?
114. The lower the blood/gas solubility coefficient, the faster the
rise of the anesthetic in the lungs?--- correct answer --- Principle
,regarding blood/gas solubility coeflcient and alveolar
concentration?
115. Nitrous oxide is faster than desflurane in spite of a higher
BGC due to the concentration effect. Nitrous is administered at 50-
70% versus desflurane at less than 10%?--- correct answer ---
What is true regarding nitrous vs desflurane speed?
116. Tells you how fast anesthetics go into the lungs (fraction of
alveoli/fraction inspired)?--- correct answer --- What is FA/FI
ratio?
117. the faster you breathe, the faster you go to sleep (reach a
higher alveolar concentration faster)?--- correct answer ---
Principle related to breathing and sleep speed?
118. the higher the dose, the faster it works?--- correct answer ---
Principle regarding concentration and speed of drug?
119. Your Fa goes up faster?--- correct answer --- If you increase
the % of a drug given, what happens?
120. Fast in, fast out?--- correct answer --- rule of thumb regarding
a low blood gas solubility?
121. slow in and out?--- correct answer --- rule of thumb regarding
a high solubility for blood/gas?
122. not; rapidly?--- correct answer --- An anesthetic with a low
blood/gas solubility is taken into the blood, therefore, the
alveolar/brain concentration rises
123. slows the delivery of all anesthetics?--- correct answer --- A
ventilation/perfusion deficit does what to all anesthetics?
,124. the fastest (lowest blood/gas coefficients)?--- correct answer
--- What type of anesthetics are attected the most by a V/Q deficit?
125. Go to sleep more slowly, the faster gases have a more
noticeably slower sleep time?--- correct answer --- What are two
characteristics of bad lungs and anesthetics?
126. 1.) Use a very low solubility agent (N20), along with another
agent with higher solubility
2.) Use high concentrations of the fast (low solubility) drug (N2O)?-
-- correct answer --- What are the two necessary components of the
second gas ettect?
127. with pneumothorax, bowel obstruction, inner ear surgery,
neurosurgical procedures with air injections, VAE, within 4 weeks
of a sulfar hexafluoride gas injection for ocular surgery,
laparoscopy, and in expansion of the ET tube cuff or PAC balloon?---
correct answer --- When can nitrous oxide gas expansion be bad?
128. turn it off?--- correct answer --- What should you do with
nitrous before closure during ENT cases?
129. N2O?--- correct answer --- Don't use what in a bowel
obstruction?
130. 10%?--- correct answer --- What percent of body mass are the
vessel-rich tissue (vital organs)?
131. 75% of CO?--- correct answer --- % perfusion the vessel-rich
tissues receive?
132. 4 L/min?--- correct answer --- How much flow do the vessel
rich tissues receive?
, 133. 50%?--- correct answer --- Percentage of body mass for
muscle?
134. 19% of CO?--- correct answer --- % perfusion for muscles?
135. 1 L/min?--- correct answer --- Flow of muscle tissue?
136. 20%?--- correct answer --- Percentage of fat in body mass?
137. 6% of CO?--- correct answer --- % perfusion of fat?
138. 0.4 L/min?--- correct answer --- Flow to fat?
139. 20%?--- correct answer --- Percentage of body mass for
vessel-poor tissue?
140. 0% of CO?--- correct answer --- perfusion of vessel-poor
tissue?
141. 0 L/min?--- correct answer --- Flow of vessel-poor tissue?
142. increases in cardiac output slow the onset of all anesthetics
(the highest blood gas agents are affected the most)?--- correct
answer --- Principle of cardiac output and anesthetics?
143. their onset will be slowed the most
(Will notice more of an effect on the slower gasses)?--- correct
answer --- How will higher BGC drugs be attected with tachycardia
and increased CO during induction?
144. it is faster?--- correct answer --- If heart rate and CO are low,
how is induction attected?
145. during emergence (waking up)?--- correct answer --- When
does dittusion hypoxia occur?
