TESTBANK f
RUBIN'SPATHOLOGY: CLINICOPATHOLOGIC FOUNDATIONS OF MEDICINE
f f f f f f
7TH EDITION
f
DAVID S. STRAYER, EMANUEL RUBIN
f f f f
,TestfBankfRubin'sfPathology:fClinicopathologicfFoundationsfoffMedicinef7thfEdition
TablefoffContents:
Chapterf1:fCellfAdaptation,fInjuryfandfDeath
Chapterf2:f Inflammation
Chapterf3:fRepair,fRegenerationfandfFibrosis
Chapterf4:f Immunopathology
Chapterf5:fNeoplasia
Chapterf6:fDevelopmentalfandfGeneticfDiseases
Chapterf7:fHemodynamicfDisorders
Chapterf8:fEnvironmentalfandfNutritionalfPathology
Chapterf9:fInfectiousfandfParasiticfDiseases
SectionfII:fPathogenesisfoffSystemicfConditionsfExpandablefsection
Chapterf10:fAging
Chapterf11:fSystemicfAutoimmunefDiseases
Chapterf12:fSepsis
Chapterf13:fObesityfandfDiabetesfMellitus
Chapterf14:fThefPathologyfoffPregnancy
Chapterf15:fThefAmyloidoses
SectionfIII:fDiseasesfoffIndividualfOrganfSystemsExpandablefsection
Chapterf16:fBloodfVessels
Chapterf17:fThefHeart
Chapterf18:fThefRespiratoryfSystem
Chapterf19:fThefGastrointestinalfTract
Chapterf20:fThefLiverfandfBiliaryfSystem
Chapterf21:fThefPancreas
Chapterf22:fThefKidney
Chapterf23:fThefLowerfUrinaryfTractfandfMalefReproductivefSystem
Chapterf24:fThefFemalefReproductivefSystemfandfPeritoneum
Chapterf25:fThefBreast
Chapterf26:fHematopathology
Chapterf27:fThefEndocrinefSystem
Chapterf28:fThefSkin
Chapterf29:fThefHeadfandfNeck
Chapterf30:fBones,fJointsfandfSoftfTissue
Chapterf31:fSkeletalfMusclefandfPeripheralfNervousfSystem
Chapterf32:fThefCentralfNervousfSystem
Chapterf33:fThefEye
Chapterf34:fForensicfPathology
,Rubin'sfPathology:fClinicopathologicfFoundationsfoffMedicineChapterf
1:fCellfAdaptation,fInjuryfandfDeath
Ischemiafandfotherftoxicfinjuriesfincreasefthefaccumulationfoffintracellularfcalciumfasfafresult
1. of:
A) releasefoffstoredfcalciumffromfthefmitochondria.
B) improvedfintracellularfvolumefregulation.
C) decreasedfinfluxfacrossfthefcellfmembrane.
D) attractionfoffcalciumftoffattyfinfiltrates.
Thefpatientfisffoundftofhavefliverfdisease,fresultingfinfthefremovalfoffaflobefoffhisfliver.
2. Adaptationftofthefreducedfsizefoffthefliverfleadsftof_ offthefremainingfliverfcells.
A) metaplasia
B) organfatrophy
C) compensatoryfhyperplasia
D) physiologicfhypertrophy
Afpersonfeatingfpeanutsfstartsfchokingfandfcollapses.fHisfairwayfobstructionfisfpartiallyfcleared,f
butfhefremainsfhypoxicfuntilfhefreachesfthefhospital.fThefprolongedfcellfhypoxia
3. causedfafcerebralfinfarctionfandfresulting _finfthefbrain.
A) caspasefactivation
B) coagulationfnecrosis
C) rapidfphagocytosis
D) proteinfp53fdeficiency
Bacteriafandfvirusesfcausefcellfdamagefby ,fwhichfisfuniqueffromfthefintracellular
4. damagefcausedfbyfotherfinjuriousfagents.
A) disruptingfthefsodium/potassiumfATPasefpump
B) interruptingfoxidativefmetabolismfprocesses
C) replicatingfandfproducingfcontinuedfinjury
D) decreasingfproteinfsynthesisfandffunction
Thefpatientfhasfafprolongedfinterruptionfinfarterialfbloodfflowftofhisfleftfkidney,fcausing
5. hypoxicfcellfinjuryfandfthefreleasefofffreefradicals.fFreefradicalsfdamagefcellsfby:
A) destroyingfphospholipidsfinfthefcellfmembrane.
B) alteringfthefimmunefresponsefoffthefcell.
C) disruptingfcalciumfstoragefinfthefcell.
D) inactivationfoffenzymesfandfmitochondria.
, 6. Injuredfcellsfhavefimpairedfflowfoffsubstancesfthroughfthefcellfmembranefasfafresultfof:
A) increasedffatfload.
B) alteredfpermeability.
C) alteredfglucosefutilization.
D) increasedfsurfacefreceptors.
7. Reversiblefadaptivefintracellularfresponsesfarefinitiatedfby:
A) stimulusfoverload.
B) geneticfmutations.
C) chemicalfmessengers.
D) mitochondrialfDNA.
8. Injuredfcellsfbecomefveryfswollenfasfafresultfof:
A) increasedfcellfproteinfsynthesis.
B) alteredfcellfvolumefregulation.
C) passivefentryfoffpotassiumfintofthefcell.
D) blebfformationfinfthefplasmafmembrane.
Afdiabeticfpatientfhasfimpairedfsensation,fcirculation,fandfoxygenationfoffhisffeet.fHefstepsfonfafpi
ecefoffglass,fthefwoundfdoesfnotfheal,fandfthefareaftissuefbecomesfnecrotic.fThefnecrotic
9. cellfdeathfisfcharacterizedfby:
A) rapidfapoptosis.
B) cellularfrupture.
C) shrinkagefandfcollapse.
D) chronicfinflammation.
Af99-year-oldfwomanfhasfexperiencedfthefdeclinefoffcellffunctionfassociatedfwithfage.fA
10. groupfofftheoriesfoffcellularfagingffocusfonfprogrammed:
A) changesfwithfgeneticfinfluences.
B) eliminationfoffcellfreceptorfsites.
C) insufficientftelomerasefenzyme.
D) DNAfmutationforffaultyfrepair.
Anf89-year-
oldffemalefpatientfhasfexperiencedfsignificantfdecreasesfinfherfmobilityfandfstaminafduringfaf3-
weekfhospitalfstayfforftheftreatmentfoffaffemoralfheadffracture.fWhichfofftheffollowingfphenomen
afmostflikelyfaccountsfforfthefpatientsfdecreasefinfmuscleffunction
11. thatfunderliesfherfreducedfmobility?
A) Impairedfmusclefcellfmetabolismfresultingffromfmetaplasia
B) Dysplasiafasfafconsequencefoffinflammationfduringfbonefremodeling
C) Disusefatrophyfoffmusclef cellsfduringfafprolongedfperiodfoffimmobility
RUBIN'SPATHOLOGY: CLINICOPATHOLOGIC FOUNDATIONS OF MEDICINE
f f f f f f
7TH EDITION
f
DAVID S. STRAYER, EMANUEL RUBIN
f f f f
,TestfBankfRubin'sfPathology:fClinicopathologicfFoundationsfoffMedicinef7thfEdition
TablefoffContents:
Chapterf1:fCellfAdaptation,fInjuryfandfDeath
Chapterf2:f Inflammation
Chapterf3:fRepair,fRegenerationfandfFibrosis
Chapterf4:f Immunopathology
Chapterf5:fNeoplasia
Chapterf6:fDevelopmentalfandfGeneticfDiseases
Chapterf7:fHemodynamicfDisorders
Chapterf8:fEnvironmentalfandfNutritionalfPathology
Chapterf9:fInfectiousfandfParasiticfDiseases
SectionfII:fPathogenesisfoffSystemicfConditionsfExpandablefsection
Chapterf10:fAging
Chapterf11:fSystemicfAutoimmunefDiseases
Chapterf12:fSepsis
Chapterf13:fObesityfandfDiabetesfMellitus
Chapterf14:fThefPathologyfoffPregnancy
Chapterf15:fThefAmyloidoses
SectionfIII:fDiseasesfoffIndividualfOrganfSystemsExpandablefsection
Chapterf16:fBloodfVessels
Chapterf17:fThefHeart
Chapterf18:fThefRespiratoryfSystem
Chapterf19:fThefGastrointestinalfTract
Chapterf20:fThefLiverfandfBiliaryfSystem
Chapterf21:fThefPancreas
Chapterf22:fThefKidney
Chapterf23:fThefLowerfUrinaryfTractfandfMalefReproductivefSystem
Chapterf24:fThefFemalefReproductivefSystemfandfPeritoneum
Chapterf25:fThefBreast
Chapterf26:fHematopathology
Chapterf27:fThefEndocrinefSystem
Chapterf28:fThefSkin
Chapterf29:fThefHeadfandfNeck
Chapterf30:fBones,fJointsfandfSoftfTissue
Chapterf31:fSkeletalfMusclefandfPeripheralfNervousfSystem
Chapterf32:fThefCentralfNervousfSystem
Chapterf33:fThefEye
Chapterf34:fForensicfPathology
,Rubin'sfPathology:fClinicopathologicfFoundationsfoffMedicineChapterf
1:fCellfAdaptation,fInjuryfandfDeath
Ischemiafandfotherftoxicfinjuriesfincreasefthefaccumulationfoffintracellularfcalciumfasfafresult
1. of:
A) releasefoffstoredfcalciumffromfthefmitochondria.
B) improvedfintracellularfvolumefregulation.
C) decreasedfinfluxfacrossfthefcellfmembrane.
D) attractionfoffcalciumftoffattyfinfiltrates.
Thefpatientfisffoundftofhavefliverfdisease,fresultingfinfthefremovalfoffaflobefoffhisfliver.
2. Adaptationftofthefreducedfsizefoffthefliverfleadsftof_ offthefremainingfliverfcells.
A) metaplasia
B) organfatrophy
C) compensatoryfhyperplasia
D) physiologicfhypertrophy
Afpersonfeatingfpeanutsfstartsfchokingfandfcollapses.fHisfairwayfobstructionfisfpartiallyfcleared,f
butfhefremainsfhypoxicfuntilfhefreachesfthefhospital.fThefprolongedfcellfhypoxia
3. causedfafcerebralfinfarctionfandfresulting _finfthefbrain.
A) caspasefactivation
B) coagulationfnecrosis
C) rapidfphagocytosis
D) proteinfp53fdeficiency
Bacteriafandfvirusesfcausefcellfdamagefby ,fwhichfisfuniqueffromfthefintracellular
4. damagefcausedfbyfotherfinjuriousfagents.
A) disruptingfthefsodium/potassiumfATPasefpump
B) interruptingfoxidativefmetabolismfprocesses
C) replicatingfandfproducingfcontinuedfinjury
D) decreasingfproteinfsynthesisfandffunction
Thefpatientfhasfafprolongedfinterruptionfinfarterialfbloodfflowftofhisfleftfkidney,fcausing
5. hypoxicfcellfinjuryfandfthefreleasefofffreefradicals.fFreefradicalsfdamagefcellsfby:
A) destroyingfphospholipidsfinfthefcellfmembrane.
B) alteringfthefimmunefresponsefoffthefcell.
C) disruptingfcalciumfstoragefinfthefcell.
D) inactivationfoffenzymesfandfmitochondria.
, 6. Injuredfcellsfhavefimpairedfflowfoffsubstancesfthroughfthefcellfmembranefasfafresultfof:
A) increasedffatfload.
B) alteredfpermeability.
C) alteredfglucosefutilization.
D) increasedfsurfacefreceptors.
7. Reversiblefadaptivefintracellularfresponsesfarefinitiatedfby:
A) stimulusfoverload.
B) geneticfmutations.
C) chemicalfmessengers.
D) mitochondrialfDNA.
8. Injuredfcellsfbecomefveryfswollenfasfafresultfof:
A) increasedfcellfproteinfsynthesis.
B) alteredfcellfvolumefregulation.
C) passivefentryfoffpotassiumfintofthefcell.
D) blebfformationfinfthefplasmafmembrane.
Afdiabeticfpatientfhasfimpairedfsensation,fcirculation,fandfoxygenationfoffhisffeet.fHefstepsfonfafpi
ecefoffglass,fthefwoundfdoesfnotfheal,fandfthefareaftissuefbecomesfnecrotic.fThefnecrotic
9. cellfdeathfisfcharacterizedfby:
A) rapidfapoptosis.
B) cellularfrupture.
C) shrinkagefandfcollapse.
D) chronicfinflammation.
Af99-year-oldfwomanfhasfexperiencedfthefdeclinefoffcellffunctionfassociatedfwithfage.fA
10. groupfofftheoriesfoffcellularfagingffocusfonfprogrammed:
A) changesfwithfgeneticfinfluences.
B) eliminationfoffcellfreceptorfsites.
C) insufficientftelomerasefenzyme.
D) DNAfmutationforffaultyfrepair.
Anf89-year-
oldffemalefpatientfhasfexperiencedfsignificantfdecreasesfinfherfmobilityfandfstaminafduringfaf3-
weekfhospitalfstayfforftheftreatmentfoffaffemoralfheadffracture.fWhichfofftheffollowingfphenomen
afmostflikelyfaccountsfforfthefpatientsfdecreasefinfmuscleffunction
11. thatfunderliesfherfreducedfmobility?
A) Impairedfmusclefcellfmetabolismfresultingffromfmetaplasia
B) Dysplasiafasfafconsequencefoffinflammationfduringfbonefremodeling
C) Disusefatrophyfoffmusclef cellsfduringfafprolongedfperiodfoffimmobility
