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What layer do neural crest cells develop from?
Ans: Ectoderm
At what embryonic age does the dental lamina begin to develop?
Ans: 6 weeks
What are the three components of the tooth bud?
Ans: Enamel Organ
Dental papilla
Dental sac
,What are the three morphologic stages of a developing tooth bud?
Ans: Bud stage
Cap stage
Bell stage
During the bell stage invagination of the epithelium occurs, which layer is essential for enamel
production?
Ans: Stratum intermedium
Which cells does the stellate reticulum support and protect?
Ans: Ameloblasts
What do remnants of Hertwig's epithelial root sheath persist as?
Ans: Rests of Malassez
What is the origin of the dental papilla?
Ans: Neural crest cells
What does the dental papilla differentiate in to?
Ans: Dentin and primordium of pulp
,What are enamel pearls?
Ans: Cells of epithelial root sheath that remain attached to dentin. Differentiate into ameloblasts and
produce enamel
What are the 7 steps (in order) of histophyisological differentiation of a tooth bud?
Ans: Initiation
Proliferation
Histodifferentiation
Morphodifferentiation
Apposition
Mineralization
Maturation
During which stage of tooth development may problems that lead to anomalies of tooth number occur?
Ans: Initiation
Which three stages of tooth development encompasses the bud, cap, early bell and late bell?
Ans: Proliferation
Histodifferentiation
Morphodifferentiation
, Disruptions of proliferation may result in what type of tooth anomalies? (4)
Ans: Size
Proportion
Numbers
Twinning
Which stage of tooth development may lead to anomalies of the enamel, dentin, and cementum?
Ans: Morphodifferentiation
What is the incidence of hyperdontia? Males vs females?
Ans: 0.3 - 3%
Males 2:1 females
Is hyperdontia more common in maxilla or mandible? More common in primary teeth or permanent
teeth?
Ans: Maxilla 90%
Permanent dentition 5x more common that primary
Which permanent teeth are most frequently missing? List in order from most to least common
Ans: Third molars
Mandibular second pre molars