Metabolic and Degenerative Arthropathies: Clinical Insights into Gout, CPPD, HADD, and Related Joint Disorders

Metabolic and Degenerative Arthropathies:
Clinical Insights into Gout, CPPD, HADD,
and Related Joint Disorders

What three metabolic arthropathies did we study in class? - ✔✔
- Gout

- Calcium Pyrophosphate Dihydrate Deposition Disease (CPPD)

- Hydroxyapatite Deposition Disease (HADD)



What happens in gout? - ✔✔monosodium urate crystal deposes in the joints



What do you see clinically with gout? - ✔✔Red, hot, swollen joint



Where does gout mostly deposit? - ✔✔1st MTP



What are the 5 stages of gout? - ✔✔
- asymptomatic hyperuricemia

- acute gout

- intercritical gout

- chronic tophaceous gout

- gout nephropathy



What's the gold standard for the diagnosis of gout? - ✔✔joint aspirate



What radiographic findings are present with gout? - ✔✔
- soft tissue swelling

- intial preservation of the joint space

- Tophi

- bone erosions