ASCP Hematology Exam Questions and
answers 2025
>20% .defines .what .type .of .leukemia? .- .ANS✓✓-acute
4 .deleted .alpha .genes .can .result .in .the .development .of? .- .ANS✓✓-
hydrops .fetalis, .nonviable .fetus
A .cold .agglutinin .screen .determines? .- .ANS✓✓-
the .presence .of .a .cold .autoantibody
A .falsely .decreased .ESR .can .be .attributed .to? .- .ANS✓✓-
QNS .specimen, .decreased .temperature
A .falsely .elevated .ESR .can .be .attributed .to? .- .ANS✓✓-
tilting .tube, .standing .too .long, .increased .temperature, .excess .EDTA
A .G6PD .deficiency .is .characterized .by .what .lab .findings? .- .ANS✓✓-
decreased .G6PD, .heinz .bodies
A .heinz .body .prep .can .indicate .what .conditions? .- .ANS✓✓-
G6PD .deficiency, .unstable .hemoglobins, .HbH
A .kleihauer-betke .acid .elution .measures? .- .ANS✓✓-
the .resistance .of .fetal .hemoglobin .to .acid .elution
A .left .shift .in .the .hemoglobin-
oxygen .dissociation .curve .causes .what .changes .in .the .following .substances: .C
O2, .pH, .2,3-DPG? .- .ANS✓✓-increased .pH, .decreased .CO2, .decreased .2,3-DPG
A .normal .schilling .test .with .IF .indicates .what .type .of .problem .or .anemia? .- .AN
S✓✓-pernicious .anemia
A .PK .deficiency .is .characterized .by .what .lab .findings? .- .ANS✓✓-decreased .PK,
.no .heinz .bodies
A .positive .Ham's .test .and .a .positive .sucrose .hemolysis .test .helps .to .diagnose .
what .condition .- .ANS✓✓-PNH
A .reticulocyte .production .< .2 .indicates? .- .ANS✓✓-
inadequate .bone .marrow .response .to .anemia
,A .reticulocyte .production .> .2 .indicates? .- .ANS✓✓-
adequate .bone .marrow .response .to .anemia
A .right .shift .in .the .hemoglobin-oxygen .dissociation .curve .causes .what .changes
.in .the .following .substances: .CO2, .pH, .2,3-DPG? .- .ANS✓✓-
decreased .pH, .increased .CO2, .increased .2,3-DPG
A .sickle .cell .screen .measures? .- .ANS✓✓-
the .reduced .solubility .of .deoxygenated .hemoglobin .S
A .t(15;17) .genetic .aberration .is .associated .with .what .condition? .- .ANS✓✓-
M3 .AML
A .t(8;21) .genetic .aberration .is .associated .with .what .condition? .- .ANS✓✓-
M3 .AML
A .t(9:22) .Philadelphia .chromosome .is .associated .with .what .condition? .- .ANS✓
✓-CML
A .WBC .differential .is .performed .on .a .bone .marrow .in .order .to .do .what? .- .ANS
✓✓-determine .the .type .of .leukemia .present .if .diagnosed
Acanthocytes .are .commonly .seen .in .what .condition(s)? .- .ANS✓✓-
severe .liver .disease, .abetalipoproteinemia
Alder-Reilly .is .an .anomaly .which .is .characterized .by? .- .ANS✓✓-
large .azurophilic .granules .
(due .to .the .increased .presence .of .mucopolysaccharides)
All .non-
embryonic .hemoglobin .types .are .comprised .of .what .type .of .globin .chain? .- .AN
S✓✓-alpha
An .11q/23 .genetic .aberration .is .associated .with .what .condition? .- .ANS✓✓-
M5 .AML
An .abnormal .schilling .test .with .or .without .IF .indicates .what .type .of .problem .or .
anemia? .- .ANS✓✓-malabsorption .problem
An .increase .in .hemoglobin .F .can .cause .what .kind .of .shift .in .the .hemoglobin-
oxygen .dissociation .curve? .- .ANS✓✓-left .shift
An .increase .in .liver .enzymes, .target .cells, .and .round .macrocytes .can .indicate .
what .conditions/problems? .- .ANS✓✓-liver .disease, .alcholism
An .increase .in .the .ESR .value .is .see .in .conditions .involving? .- .ANS✓✓-
the .presence .of .abnormal .plasma .proteins .(inflammatory .conditions)
, An .increased .MCV .with .MCHC .and .decreased .RBC .is .associated .with .what .con
dition? .- .ANS✓✓-cold .agglutinin .disease
Another .name .for .helmet .cells .is? .- .ANS✓✓-keratocyte
Another .word .for .sickle .cells .is? .- .ANS✓✓-drepanocyte
Anti-malarial .drugs .and .fava .beans .can .exacerbate .what .condition? .- .ANS✓✓-
G6PD .deficiency
Are .Dohle .bodies .present .in .a .leukemoid .reaction .or .CML? .- .ANS✓✓-leukemoid
.reaction
Auer .rods .are .diagnostic .for .what .condition? .- .ANS✓✓-AML
Basophil .counts .are .increased .in .what .conditions? .- .ANS✓✓-
immediate .hypersensitivies
Bone .marrow .biopsies .are .performed .to .in .order .to .evaulate .what? .- .ANS✓✓-
overall .cellularity .of .the .bone .marrow
Burkitt's .lymphoma .falls .under .which .classification .of .ALL? .- .ANS✓✓-L3
Cutaneous .symptoms .such .as .photo-
sensitivity .and .facial .hair .are .seen .when .a .build .up .of .which .precursors .occurs
? .- .ANS✓✓-
later .precursors .(uroporphyrinogen/coproporphyrinogen, .protoporphyrin/heme)
Dohle .bodies .are .associated .with .what .condition(s)? .- .ANS✓✓-
bacterial .infections, .burns, .May-Hegglin
Dry .bone .marrow .taps .are .associated .with .what .pathological .condition(s)? .- .AN
S✓✓-myelofibrosis, .aplastic .anemia
Echinocytes .are .commonly .seen .in .what .condition(s)? .- .ANS✓✓-uremia .
(can .also .be .an .artifact)
Elliptocytes .are .commonly .seen .in .what .condition(s)? .- .ANS✓✓-
hereditary .elliptocytosis, .iron .deficiency, .thalassemia
Eosinophil .counts .are .increased .in .what .conditions? .- .ANS✓✓-
allergies, .parasites
Excess .Iron .is .stored .where? .What .does .this .cause? .- .ANS✓✓-
tissues .and .body .organs, .hemosiderosis, .hemochromatosis
Gaucher's .disease .is .characterized .by .an .increase .in .what? .- .ANS✓✓-
glucocerebroside
answers 2025
>20% .defines .what .type .of .leukemia? .- .ANS✓✓-acute
4 .deleted .alpha .genes .can .result .in .the .development .of? .- .ANS✓✓-
hydrops .fetalis, .nonviable .fetus
A .cold .agglutinin .screen .determines? .- .ANS✓✓-
the .presence .of .a .cold .autoantibody
A .falsely .decreased .ESR .can .be .attributed .to? .- .ANS✓✓-
QNS .specimen, .decreased .temperature
A .falsely .elevated .ESR .can .be .attributed .to? .- .ANS✓✓-
tilting .tube, .standing .too .long, .increased .temperature, .excess .EDTA
A .G6PD .deficiency .is .characterized .by .what .lab .findings? .- .ANS✓✓-
decreased .G6PD, .heinz .bodies
A .heinz .body .prep .can .indicate .what .conditions? .- .ANS✓✓-
G6PD .deficiency, .unstable .hemoglobins, .HbH
A .kleihauer-betke .acid .elution .measures? .- .ANS✓✓-
the .resistance .of .fetal .hemoglobin .to .acid .elution
A .left .shift .in .the .hemoglobin-
oxygen .dissociation .curve .causes .what .changes .in .the .following .substances: .C
O2, .pH, .2,3-DPG? .- .ANS✓✓-increased .pH, .decreased .CO2, .decreased .2,3-DPG
A .normal .schilling .test .with .IF .indicates .what .type .of .problem .or .anemia? .- .AN
S✓✓-pernicious .anemia
A .PK .deficiency .is .characterized .by .what .lab .findings? .- .ANS✓✓-decreased .PK,
.no .heinz .bodies
A .positive .Ham's .test .and .a .positive .sucrose .hemolysis .test .helps .to .diagnose .
what .condition .- .ANS✓✓-PNH
A .reticulocyte .production .< .2 .indicates? .- .ANS✓✓-
inadequate .bone .marrow .response .to .anemia
,A .reticulocyte .production .> .2 .indicates? .- .ANS✓✓-
adequate .bone .marrow .response .to .anemia
A .right .shift .in .the .hemoglobin-oxygen .dissociation .curve .causes .what .changes
.in .the .following .substances: .CO2, .pH, .2,3-DPG? .- .ANS✓✓-
decreased .pH, .increased .CO2, .increased .2,3-DPG
A .sickle .cell .screen .measures? .- .ANS✓✓-
the .reduced .solubility .of .deoxygenated .hemoglobin .S
A .t(15;17) .genetic .aberration .is .associated .with .what .condition? .- .ANS✓✓-
M3 .AML
A .t(8;21) .genetic .aberration .is .associated .with .what .condition? .- .ANS✓✓-
M3 .AML
A .t(9:22) .Philadelphia .chromosome .is .associated .with .what .condition? .- .ANS✓
✓-CML
A .WBC .differential .is .performed .on .a .bone .marrow .in .order .to .do .what? .- .ANS
✓✓-determine .the .type .of .leukemia .present .if .diagnosed
Acanthocytes .are .commonly .seen .in .what .condition(s)? .- .ANS✓✓-
severe .liver .disease, .abetalipoproteinemia
Alder-Reilly .is .an .anomaly .which .is .characterized .by? .- .ANS✓✓-
large .azurophilic .granules .
(due .to .the .increased .presence .of .mucopolysaccharides)
All .non-
embryonic .hemoglobin .types .are .comprised .of .what .type .of .globin .chain? .- .AN
S✓✓-alpha
An .11q/23 .genetic .aberration .is .associated .with .what .condition? .- .ANS✓✓-
M5 .AML
An .abnormal .schilling .test .with .or .without .IF .indicates .what .type .of .problem .or .
anemia? .- .ANS✓✓-malabsorption .problem
An .increase .in .hemoglobin .F .can .cause .what .kind .of .shift .in .the .hemoglobin-
oxygen .dissociation .curve? .- .ANS✓✓-left .shift
An .increase .in .liver .enzymes, .target .cells, .and .round .macrocytes .can .indicate .
what .conditions/problems? .- .ANS✓✓-liver .disease, .alcholism
An .increase .in .the .ESR .value .is .see .in .conditions .involving? .- .ANS✓✓-
the .presence .of .abnormal .plasma .proteins .(inflammatory .conditions)
, An .increased .MCV .with .MCHC .and .decreased .RBC .is .associated .with .what .con
dition? .- .ANS✓✓-cold .agglutinin .disease
Another .name .for .helmet .cells .is? .- .ANS✓✓-keratocyte
Another .word .for .sickle .cells .is? .- .ANS✓✓-drepanocyte
Anti-malarial .drugs .and .fava .beans .can .exacerbate .what .condition? .- .ANS✓✓-
G6PD .deficiency
Are .Dohle .bodies .present .in .a .leukemoid .reaction .or .CML? .- .ANS✓✓-leukemoid
.reaction
Auer .rods .are .diagnostic .for .what .condition? .- .ANS✓✓-AML
Basophil .counts .are .increased .in .what .conditions? .- .ANS✓✓-
immediate .hypersensitivies
Bone .marrow .biopsies .are .performed .to .in .order .to .evaulate .what? .- .ANS✓✓-
overall .cellularity .of .the .bone .marrow
Burkitt's .lymphoma .falls .under .which .classification .of .ALL? .- .ANS✓✓-L3
Cutaneous .symptoms .such .as .photo-
sensitivity .and .facial .hair .are .seen .when .a .build .up .of .which .precursors .occurs
? .- .ANS✓✓-
later .precursors .(uroporphyrinogen/coproporphyrinogen, .protoporphyrin/heme)
Dohle .bodies .are .associated .with .what .condition(s)? .- .ANS✓✓-
bacterial .infections, .burns, .May-Hegglin
Dry .bone .marrow .taps .are .associated .with .what .pathological .condition(s)? .- .AN
S✓✓-myelofibrosis, .aplastic .anemia
Echinocytes .are .commonly .seen .in .what .condition(s)? .- .ANS✓✓-uremia .
(can .also .be .an .artifact)
Elliptocytes .are .commonly .seen .in .what .condition(s)? .- .ANS✓✓-
hereditary .elliptocytosis, .iron .deficiency, .thalassemia
Eosinophil .counts .are .increased .in .what .conditions? .- .ANS✓✓-
allergies, .parasites
Excess .Iron .is .stored .where? .What .does .this .cause? .- .ANS✓✓-
tissues .and .body .organs, .hemosiderosis, .hemochromatosis
Gaucher's .disease .is .characterized .by .an .increase .in .what? .- .ANS✓✓-
glucocerebroside
