NURS 6645 WEEK 11 FINAL EXAM QUESTIONS AND ANSWERS
LATEST () (VERIFIED ANSWERS)100% CORRECT ALREADY
GRADED A+
1.
When prescribing an SSRI for major depressive disorder, what is the most common
mechanism through which these agents exert their antidepressant effect?
A) Blockade of dopamine D2 receptors
B) Inhibition of serotonin reuptake at the presynaptic neuron
C) Increase in acetylcholine release
D) Enhancement of norepinephrine degradation
Correct Answer: B) Inhibition of serotonin reuptake at the presynaptic
neuron
2.
Which antidepressant is most likely to cause weight loss and is also used to aid in
smoking cessation?
A) Fluoxetine
B) Bupropion
C) Mirtazapine
D) Sertraline
Correct Answer: B) Bupropion
3.
A patient on lithium presents with tremor, nausea, and confusion. What is the best
immediate action?
,A) Continue lithium and recheck in one week
B) Stop lithium and assess serum lithium level immediately
C) Increase fluid restriction
D) Add valproate for tremor control
Correct Answer: B) Stop lithium and assess serum lithium level immediately
4.
Why should SSRIs and MAOIs never be co-administered?
A) They cause hypertensive crisis due to norepinephrine depletion
B) They can lead to serotonin syndrome, a life-threatening condition
C) They block each other’s absorption
D) They increase risk of tardive dyskinesia
Correct Answer: B) They can lead to serotonin syndrome, a life-threatening
condition
5.
Which of the following medications is considered first-line for generalized anxiety
disorder (GAD)?
A) Alprazolam
B) Sertraline
C) Haloperidol
D) Buspirone only
Correct Answer: B) Sertraline
6.
Why is clozapine reserved for treatment-resistant schizophrenia?
A) It has poor efficacy compared to other antipsychotics
B) It carries risk of agranulocytosis requiring regular CBC monitoring
C) It cannot cross the blood-brain barrier
,D) It causes only mild sedation
Correct Answer: B) It carries risk of agranulocytosis requiring regular CBC
monitoring
7.
Which side effect is most associated with first-generation (typical) antipsychotics
such as haloperidol?
A) Weight gain
B) Extrapyramidal symptoms (EPS)
C) Increased libido
D) Hypotension only
Correct Answer: B) Extrapyramidal symptoms (EPS)
8.
What is the main mechanism of action of benzodiazepines in treating anxiety
disorders?
A) Enhancement of GABA-A receptor activity leading to increased inhibitory
neurotransmission
B) Blockade of serotonin reuptake
C) Inhibition of NMDA receptors
D) Stimulation of dopamine release in the prefrontal cortex
Correct Answer: A) Enhancement of GABA-A receptor activity leading to
increased inhibitory neurotransmission
9.
A patient taking MAOI reports eating aged cheese and now complains of headache
and palpitations. What is the likely cause?
A) Hypoglycemia
B) Hypertensive crisis from tyramine interaction
, C) Serotonin deficiency
D) Anticholinergic toxicity
Correct Answer: B) Hypertensive crisis from tyramine interaction
10.
Which medication is considered safest for managing depression in pregnancy?
A) Paroxetine
B) Sertraline
C) Lithium
D) Venlafaxine
Correct Answer: B) Sertraline
11.
What is the black box warning associated with all antidepressants, especially in
younger patients?
A) Increased risk of suicidal thoughts and behaviors
B) Severe hepatic failure
C) Long QT syndrome
D) Increased appetite and obesity
Correct Answer: A) Increased risk of suicidal thoughts and behaviors
12.
In bipolar disorder, why is antidepressant monotherapy contraindicated?
A) It can precipitate mania or rapid cycling episodes
B) It increases risk of agranulocytosis
C) It lowers serum sodium excessively
D) It worsens negative symptoms
Correct Answer: A) It can precipitate mania or rapid cycling episodes
LATEST () (VERIFIED ANSWERS)100% CORRECT ALREADY
GRADED A+
1.
When prescribing an SSRI for major depressive disorder, what is the most common
mechanism through which these agents exert their antidepressant effect?
A) Blockade of dopamine D2 receptors
B) Inhibition of serotonin reuptake at the presynaptic neuron
C) Increase in acetylcholine release
D) Enhancement of norepinephrine degradation
Correct Answer: B) Inhibition of serotonin reuptake at the presynaptic
neuron
2.
Which antidepressant is most likely to cause weight loss and is also used to aid in
smoking cessation?
A) Fluoxetine
B) Bupropion
C) Mirtazapine
D) Sertraline
Correct Answer: B) Bupropion
3.
A patient on lithium presents with tremor, nausea, and confusion. What is the best
immediate action?
,A) Continue lithium and recheck in one week
B) Stop lithium and assess serum lithium level immediately
C) Increase fluid restriction
D) Add valproate for tremor control
Correct Answer: B) Stop lithium and assess serum lithium level immediately
4.
Why should SSRIs and MAOIs never be co-administered?
A) They cause hypertensive crisis due to norepinephrine depletion
B) They can lead to serotonin syndrome, a life-threatening condition
C) They block each other’s absorption
D) They increase risk of tardive dyskinesia
Correct Answer: B) They can lead to serotonin syndrome, a life-threatening
condition
5.
Which of the following medications is considered first-line for generalized anxiety
disorder (GAD)?
A) Alprazolam
B) Sertraline
C) Haloperidol
D) Buspirone only
Correct Answer: B) Sertraline
6.
Why is clozapine reserved for treatment-resistant schizophrenia?
A) It has poor efficacy compared to other antipsychotics
B) It carries risk of agranulocytosis requiring regular CBC monitoring
C) It cannot cross the blood-brain barrier
,D) It causes only mild sedation
Correct Answer: B) It carries risk of agranulocytosis requiring regular CBC
monitoring
7.
Which side effect is most associated with first-generation (typical) antipsychotics
such as haloperidol?
A) Weight gain
B) Extrapyramidal symptoms (EPS)
C) Increased libido
D) Hypotension only
Correct Answer: B) Extrapyramidal symptoms (EPS)
8.
What is the main mechanism of action of benzodiazepines in treating anxiety
disorders?
A) Enhancement of GABA-A receptor activity leading to increased inhibitory
neurotransmission
B) Blockade of serotonin reuptake
C) Inhibition of NMDA receptors
D) Stimulation of dopamine release in the prefrontal cortex
Correct Answer: A) Enhancement of GABA-A receptor activity leading to
increased inhibitory neurotransmission
9.
A patient taking MAOI reports eating aged cheese and now complains of headache
and palpitations. What is the likely cause?
A) Hypoglycemia
B) Hypertensive crisis from tyramine interaction
, C) Serotonin deficiency
D) Anticholinergic toxicity
Correct Answer: B) Hypertensive crisis from tyramine interaction
10.
Which medication is considered safest for managing depression in pregnancy?
A) Paroxetine
B) Sertraline
C) Lithium
D) Venlafaxine
Correct Answer: B) Sertraline
11.
What is the black box warning associated with all antidepressants, especially in
younger patients?
A) Increased risk of suicidal thoughts and behaviors
B) Severe hepatic failure
C) Long QT syndrome
D) Increased appetite and obesity
Correct Answer: A) Increased risk of suicidal thoughts and behaviors
12.
In bipolar disorder, why is antidepressant monotherapy contraindicated?
A) It can precipitate mania or rapid cycling episodes
B) It increases risk of agranulocytosis
C) It lowers serum sodium excessively
D) It worsens negative symptoms
Correct Answer: A) It can precipitate mania or rapid cycling episodes
