COMPLETE TEST BANK FOR Pathophysiology: The Biologic Basis for Disease in Adults and Children 8th Edition by Kathryn L. McCance MS PhD (Author) latest update

PATHOPHYSIOLOGY 8TH EDITION MCCANCE TEST BANK




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, PATHOPHYSIOLOGYqq8THqqEDITIONqqMCCANCEqqTESTqqBA
NK
Chapterqq1:qqCellularqqBiology


MULTIPLEqqCHOICE

1. Whichqqstatementqqbestqqdescribesqqtheqqcellularqqfunctionqqofqqmetabolicqqabsorption?
a. Cellsqqcanqqproduceqqproteins. c. Cellsqqcanqqtakeqqinqqandqquseqqnutrients.
b. Cellsqqcanqqsecreteqqdigestiveqqenzymes. d.q q Cellsqqcanqqsynthesizeqqfats.
ANS:q q C
Inqqmetabolicqqabsorption,qqallqqcellsqqtakeqqinqqandqquseqqnutrientsqqandqqotherqqsubstancesqqfro
mqqtheirqqsurroundings.qqTheqqremainingqqoptionsqqareqqnotqqinclusiveqqinqqtheirqqdescriptionsq
qofqqcellularqqmetabolicqqabsorption.



PTS:q q q q 1 REF:q q Pageqq2

2. Mostqqofqqaqqcell’sqqgeneticqqinformation,qqincludingqqRNAqqandqqDNA,qqisqqcontainedqqinqqthe:
a. Mitochondria c. Nucleolus
b. Ribosome d.q q q q Lysosome
ANS:q q C
Theqqnucleusqqcontainsqqtheqqnucleolus,qqaqqsmallqqdenseqqstructureqqcomposedqqlargelyqqofqqR
NA,qqmostqqofqqtheqqcellularqqDNA,qqandqqtheqqDNA-
bindingqqproteins,qqsuchqqasqqtheqqhistones,qqwhichqqregulateqqitsqqactivity.qqTheqqotherqqoptions
qqdoqqnotqqcontainqqmostqqofqqaqqcell’sqqgeneticqqinformation.



PTS:q q q q 1 REF:q q Pageqq2

3. Whichqqcomponentqqofqqtheqq cellqqprodNuUceRsSIhNyGd TroBg. CenO M
p eroxide qq(H2O2)qqbyqqusingqqoxy
genqqtoqqremoveqqhydrogenqqatomsqqfromqqspecificqqsubstratesqqinqqanqqoxidativeqqreactio
n?
a. Lysosomes c. Ribosomes
b. Peroxisomes d.q q Oxyhydrosomes
ANS:q q B
Peroxisomesqqareqqsoqqnamedqqbecauseqqtheyqqusuallyqqcontainqqenzymesqqthatqquseqqoxygenqqt
oqqremoveqqhydrogenqqatomsqqfromqqspecificqqsubstratesqqinqqanqqoxidativeqqreactionqqthatqqpro
ducesqqH2O2,qqwhichqqisqqaqqpowerfulqqoxidantqqandqqpotentiallyqqdestructiveqqifqqitqqaccumulat
esqqorqqescapesqqfromqqperoxisomes.qqRibosomesqqareqqRNA-
proteinqqcomplexesqq(nucleoproteins)qqthatqqareqqsynthesizedqqinqqtheqqnucleolusqqandqqsecrete
dqqintoqqtheqqcytoplasmqqthroughqqporesqqinqqtheqqnuclearqqenvelopeqqcalledqqnuclearqqporeqqco
mplexes.qqLysosomesqqareqqsaclikeqqstructuresqqthatqqoriginateqqfromqqtheqqGolgiqqcomplexqqan
dqqcontainqqmoreqqthanqq40qqdigestiveqqenzymesqqcalledqqhydrolases,qqwhichqqcatalyzeqqbondsqq
inqqproteins,qqlipids,qqnucleicqqacids,qqandqqcarbohydrates.qqOxyhydrosomesqqareqqinvolvedqqinq
qenzymeqqproduction.



PTS:q q q q 1 REF:q q Pageqq8

4. Whichqqcellqqcomponentqqisqqcapableqqofqqcellularqqautodigestionqqwhenqqitqqisqqreleasedqqduri
ngqqcellqqinjury?
a. Ribosome c. Smoothqqendoplasmicqqreticulum
b. Golgiqqcomplex d.q q Lysosomes
ANS:q q D



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, PATHOPHYSIOLOGYqq8THqqEDITIONqqMCCANCEqqTESTqqBA
NK
Theqqlysosomalqqmembraneqqactsqqasqqaqqprotectiveqqshieldqqbetweenqqtheqqpowerfulqqdigestive
qqenzymesqqwithinqqtheqqlysosomeqqandqqtheqqcytoplasm,qqpreventingqqtheirqqleakageqqintoqqtheq

qcytoplasmicqqmatrix.qqDisruptionqqofqqtheqqmembraneqqbyqqvariousqqtreatmentsqqorqqcellularqqi

njuryqqleadsqqtoqqaqqreleaseqqofqqtheqqlysosomalqqenzymes,qqwhichqqcanqqthenqqreactqqwithqqtheir
qqspecificqqsubstrates,qqcausingqqcellularqqself-

digestion.qqTheqqotherqqoptionsqqdoqqnotqqcorrectlyqqdescribeqqthisqqprocess.

PTS:q q q q 1 REF:q q Pagesqq7-8

5. Whatqqisqqtheqqsequenceqqofqqstepsqqinqqtheqqdevelopmentqqofqqaqqdigestiveqqenzymeqqbyqqtheqq
pancreasqqcellsqqfromqqtheqqinitialqqtranscriptionqqtoqqtheqqreleaseqqfromqqtheqqcell?
a. TheqqenzymeqqisqqtranscribedqqfromqqDNAqqbyqqRNAqqinqqtheqqnucleus,qqproceeds
qqtoqqtheqqribosomeqqforqqsynthesis,qqandqqisqqtransportedqqinqqaqqsecretoryqqvesicle

qqtoqqtheqqcellqqmembrane.

b. TheqqenzymeqqisqqtranscribedqqfromqqRNAqqbyqqDNAqqinqqtheqqnucleus,qqproceedsqqtoq
qtheqqlysosomeqqforqqsynthesis,qqandqqisqqtransportedqqinqqanqqencapsulatedqqmembraneq

qtoqqtheqqcellqqmembrane.

c. Theqqenzymeqqisqqtranscribedqqbyqqtheqqmitochondriaqqinqqtheqqnucleus,qqproceedsqqto
qqtheqqribosomeqqforqqsynthesis,qqandqqisqqtransportedqqinqqaqqcytoskeletonqqtoqqtheqqcell

qqmembrane.

d. TheqqenzymeqqisqqtranscribedqqfromqqDNAqqbyqqRNAqqinqqtheqqnucleus,qqproceedsqqt
oqqtheqqGolgiqqcomplexqqforqqsynthesis,qqandqqisqqtransportedqqinqqaqqcytosolqqtoqqtheqqc
ellqqmembrane.
ANS:q q A
TheqqenzymeqqisqqtranscribedqqfromqqDNAqqbyqqRNAqqinqqtheqqnucleus,qqproceedsqqtoqqtheqqrib
osomeqqforqqsynthesis,qqandqqisqqtransportedqqinqqaqqsecretoryqqvesicleqqtoqqtheqqcellqqmembran
e.qqTheqqotherqqoptionsqqdoqqnotqqcorrectlyqqdescribeqqthisqqprocess.
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PTS:q q q q 1 REF:q q Pageqq7qq|qqFigureqq1-5

6. DuringqqwhichqqphaseqqofqqtheqqcellqqcycleqqisqqDNAqqsynthesized?
a. G1 c. G2
b. S d.q q M
ANS:q q B
Theqqfourqqdesignatedqqphasesqqofqqtheqqcellqqcycleqqare:qq(1)qqtheqqG1qqphaseqq(Gqq=qqgap),qqwhi
chqqisqqtheqqperiodqqbetweenqqtheqqMqqphaseqq(Mqq=qqmitosis)qqandqqtheqqstartqqofqqDNAqqsynthesi
s;qq(2)qqtheqqSqqphaseqq(Sqq=qqsynthesis),qqduringqqwhichqqDNAqqisqqsynthesizedqqinqqtheqqcellqqn
ucleus;qq(3)qqtheqqG2qqphase,qqduringqqwhichqqRNAqqandqqproteinqqsynthesisqqoccurs,qqtheqqperi
odqqbetweenqqtheqqcompletionqqofqqDNAqqsynthesisqqandqqtheqqnextqqphaseqq(M);qqandqq(4)qqtheq
qMqqphase,qqwhichqqincludesqqnuclearqqandqqcytoplasmicqqdivision.



PTS:q q q q 1 REF:q q Pageqq37

7. Whatqqorganicqqcompoundqqfacilitatesqqtransportationqqacrossqqcellqqmembranesqqbyqqacti
ngqqasqqreceptors,qqtransportqqchannelsqqforqqelectrolytes,qqandqqenzymesqqtoqqdriveqqactiv
eqqpumps?
a. Lipids c. Proteins
b. Proteases d.q q Carbohydrates
ANS:q q C




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, PATHOPHYSIOLOGYqq8THqqEDITIONqqMCCANCEqqTESTqqBA
NK
Proteinsqqactqqasqq(1)qqrecognitionqqandqqbindingqqunitsqq(receptors)qqforqqsubstancesqqmovingq
qinqqandqqoutqqofqqtheqqcell;qq(2)qqporesqqorqqtransportqqchannelsqqforqqvariousqqelectricallyqqcha

rgedqqparticlesqqcalledqqionsqqorqqelectrolytesqqandqqspecificqqcarriersqqforqqaminoqqacidsqqandqq
monosaccharides;qqand
(3)qqspecificqqenzymesqqthatqqdriveqqactiveqqpumpsqqthatqqpromoteqqtheqqconcentrationqqofqqcer
tainqqions,qqparticularlyqqpotassiumqq(K+),qqwithinqqtheqqcellqqwhileqqkeepingqqconcentrationsqq
ofqqotherqqions,qqforqqexample,qqsodiumqq(Na+),qqbelowqqtheqqconcentrationsqqfoundqqinqqtheqqe
xtracellularqqenvironment.qqTheqqotherqqoptionsqqdoqqnotqqcorrectlyqqdescribeqqthisqqprocess.

PTS:q q q q 1 REF:q q Pageqq13qq|qqPageqq15

8. Understandingqqtheqqvariousqqstepsqqofqqproteolyticqqcascades,qqsuchqqasqqcaspase-
mediatedqqapoptosisqqandqqcomplementqqcascades,qqmayqqbeqqusefulqqinqqdesigningqqdrugqqth
erapyqqforqqwhichqqhumanqqdiseases?
a. Cardiacqqandqqvascularqqdisorders
b. Autoimmuneqqandqqmalignantqqdisorders
c. Gastrointestinalqqandqqrenalqqdisorders
d. Endocrineqqandqqgastrointestinalqqdisorders
ANS:q q B
Understandingqqtheqqvariousqqstepsqqinvolvedqqinqqthisqqprocessqqisqqcrucialqqforqqdesigningqqd
rugqqinterventions.qqDysregulationqqofqqproteasesqqfeaturesqqprominentlyqqinqqmanyqqhumanqqd
iseases,qqincludingqqcancer,qqautoimmunity,qqandqqneurodegenerativeqqdisorders.qqTheqqother
qqoptionsqqdoqqnotqqcorrectlyqqdescribeqqthisqqprocess.



PTS:q q q q 1 REF:q q q q Pageqq15

9. Whichqqstructureqqpreventsqqwater-
solubleqqmoleculesqqfromqqenteringqqcellsqqacrossqqtheqqplasmaqq
membrane?
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a. Carbohydrateqqchains c. Membraneqqchannelqqproteins
b. Glycoproteinqqchannels d.q q Lipidqqbilayer
ANS:q q D
Theqqbilayer’sqqstructureqqaccountsqqforqqoneqqofqqtheqqessentialqqfunctionsqqofqqtheqqplasmaqq
membrane.qqItqqisqqimpermeableqqtoqqmostqqwater-
solubleqqmoleculesqq(moleculesqqthatqqdissolveqqinqqwater)qqbecauseqqtheqqwater-
solubleqqmoleculesqqareqqinsolubleqqinqqtheqqoilyqqcoreqqregion.qqTheqqbilayerqqservesqqasqqaqqb
arrierqqtoqqtheqqdiffusionqqofqqwaterqqandqqhydrophilicqqsubstancesqqwhileqqallowingqqlipid-
solubleqqmolecules,qqsuchqqasqqoxygenqq(O2)qqandqqcarbonqqdioxideqq(CO2),qqtoqqdiffuseqqthro
ughqqitqqreadily.qqTheqqotherqqoptionsqqdoqqnotqqcorrectlyqqdescribeqqthisqqprocess.

PTS:q q q q 1 REF:q q Pagesqq12-13

10. Theqqfluidqqmosaicqqmodelqqexplains:
a. Howqqaqqcellqqmembraneqqfunctions
b. Whyqqourqqbodiesqqappearqqtoqqbeqqsolid
c. Howqqtissueqqisqqdifferentiated
d. Howqqfluidqqmovesqqbetweenqqtheqqintracellularqqandqqextracellularqqcompartments
ANS:q q A
Theqqfluidqqmosaicqqmodelqqaccountsqqforqqtheqqflexibilityqqofqqcellularqqmembranes,qqtheir
self-
sealingqqproperties,qqandqqtheirqqimpermeabilityqqtoqqmanyqqsubstances.qqTheqqremainingqqopti
onsqqdoqqnotqqexplainqqtheqqmosaicqqmodel.

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