NU 214-1 Medication Classification:
Antihypertensive Drugs Questions with Detailed
Verified Answers for Accuracy
Antihypertensive drugs are to...
✓✓ Treat hyperntension/bring high BP down
BP can be affected by what 3 different things?
✓✓ 1. The Pump (heart)
2. The Pipes (blood vessels)
3. The Fluid (blood; the amount of vascular volume)
BP = CO x SVR
What does this mean?
✓✓ Blood Pressure = *C*ardiac *O*utput x *S*ystemic
*V*ascular *R*esistance
CO is the amount of blood...
✓✓ Ejected from the left ventricle (hear to the body)
The SVR is determined by the...
✓✓ Diameter of the blood vessels
Hypertension is important because it can lead to _______
which can progress into....
, ACCURACY IS GUARANTEED
✓✓ CAD; MI, CVA & Renal Failure
*Hypertension is the most important risk factor/indicator for a
future MI, CVA and renal failure
Hypertension can be classified by 4 different stages. What are
they?
✓✓ 1. Normal: 90-120/60-80
2. Pre-Hypertensive: 121-139/81-89
3. Stage 1 HTN: 140-159/90-99
4. Stage 2 HTN: 160+/100+
Primary hypertension is ____% of the hypertensive cases and
is generally a result of....
✓✓ 90%; genetics, lifestyle, etc.
Secondary hypertension is ____% of the hypertensive cases
and is generally a result of...
✓✓ 10%; disease, medication, another (secondary) reason
What are the major categories of antihypertensive drugs?
✓✓ -Adrenergic Drugs
-Angiotensin Converting Enzyme (ACE) Inhibitors
-Diuretics
How do Adrenergic drugs work?
, ACCURACY IS GUARANTEED
✓✓ They affecting the sympathetic NE of the nervous system
What is the normal response of the sympathetic nervous
system?
✓✓ Fight or Flight
-d/t adrenaline
The flight or flight response acts on the _______ ___
receptors, that when stimulated cause
___________________ of the blood vessels increasing BP
✓✓ Alpha 1; vasoconstriction
Stimulation of the alpha 1 receptors also causes...
✓✓ -contractions of the sphincters in the GI and GU tract
-Mydriasis (dilation) of the pupils
Adrenergic drugs can be broken down into what sub-
catergories?
✓✓ -Alpha 1 Blockers
-Centrally Acting Alpha 2 Agonists
-Beta Blockers
-Dual Alpha 1 and Beta Receptor Blockers
*Alpha 1 Blockers*
✓✓