ALL THE COMSAE | ACTUAL EXAM 2025 LATEST UPDATED |
COMPLETE QUESTIONS WITH 100% RATED CORRECT
ANSWERS | GET IT A+
1
Which medication is a first-line agent used in the treatment of ulcerative
colitis and Crohn's disease?
A) Metronidazole
B) Sulfasalazine
C) Prednisone
D) Azathioprine
E) Infliximab
Correct Answer: B) sulfasalazine
Rationale: Sulfasalazine is an aminosalicylate commonly used as a
first-line treatment for mild to moderate inflammatory bowel
disease (IBD), including ulcerative colitis and Crohn's disease, due
to its anti-inflammatory properties in the gut.
2
The characteristic pulmonary effects observed in patients with Cystic Fibrosis
(CF) include:
A) Restrictive lung disease and pleural effusions.
B) Chronic bronchitis and bronchiectasis.
C) Pulmonary hypertension and right heart failure.
D) Acute pneumonia and ARDS.
E) Obstructive sleep apnea and central hypoventilation.
Correct Answer: B) chronic bronchitis and bronchiectasis
Rationale: Cystic Fibrosis is characterized by the production of thick,
sticky mucus, which leads to chronic airway obstruction, recurrent
infections, chronic bronchitis, and ultimately bronchiectasis
(permanent dilation of bronchi).
3
Osteoporosis primarily affects which type of bone within the skeletal system?
A) Cortical bone mass only.
,B) Trabecular (spongy) bone mass primarily.
C) Both cortical and trabecular bone equally.
D) Bone marrow density.
E) Only the compact bone of long bones.
Correct Answer: B) trabecular bone mass loss
Rationale: Osteoporosis predominantly leads to the loss of trabecular
(spongy) bone mass, which is metabolically more active and thus
more susceptible to demineralization, although cortical bone is also
affected.
4
A patient is prescribed Imipramine. Which class of antidepressants does this
drug belong to, and what are its potential serious side effects ("Tri-Cs")?
A) SSRI; Serotonin Syndrome, Sexual Dysfunction, Stomach upset.
B) SNRI; Seizures, Nausea, Insomnia.
C) TCA; Convulsions, Coma, Cardiotoxicity.
D) MAOI; Hypertensive Crisis, Hepatotoxicity.
E) Atypical Antidepressant; Weight gain, Sedation.
Correct Answer: C) TCA; Convulsions, Coma, Cardiotoxicity
Rationale: Imipramine is a tricyclic antidepressant (TCA). Overdose or
high doses can lead to the "Tri-Cs" of convulsions, coma, and
cardiotoxicity (e.g., arrhythmias, QTc prolongation), as well as
significant anticholinergic effects.
5
Which phenomenon describes the manifestation of a visceral (organ) disease
as a finding in the corresponding somatic (musculoskeletal) tissue?
A) Somatic dysfunction.
B) Viscerosomatic reflex.
C) Somatosomatic reflex.
D) Viscerovisceral reflex.
E) Referred pain.
,Correct Answer: B) viscerosomatic
Rationale: A viscerosomatic reflex is a phenomenon where localized
visceral pathology or dysfunction results in a reflex somatic
(musculoskeletal) manifestation, such as muscle spasm, tenderness,
or tissue texture changes in a corresponding dermatome/myotome
segment.
6
Which of the following drugs is a second-generation H1 blocker that typically
causes less sedation compared to first-generation H1 blockers?
A) Ranitidine
B) Cimetidine
C) Loratadine
D) Diphenhydramine
E) Famotidine
Correct Answer: C) loratidine
Rationale: Loratadine is a second-generation H1 blocker that does not
readily cross the blood-brain barrier, resulting in significantly less
sedation compared to first-generation antihistamines like
diphenhydramine.
7
A stool sample reveals cells containing phagocytosed red blood cells (RBCs).
This finding is characteristic of infection with which protozoan parasite?
A) Giardia lamblia
B) Cryptosporidium parvum
C) Entamoeba histolytica
D) Cyclospora cayetanensis
E) Balantidium coli
Correct Answer: C) entaemoba histolytica
Rationale: The presence of red blood cells (RBCs) inside trophozoites
, on a stool examination is a classic diagnostic feature of Entamoeba
histolytica infection, indicating invasive amebiasis.
8
Which type of pneumothorax causes tracheal deviation away from the
affected side?
A) Spontaneous pneumothorax
B) Iatrogenic pneumothorax
C) Open pneumothorax
D) Tension pneumothorax
E) Simple pneumothorax
Correct Answer: D) tension
Rationale: In a tension pneumothorax, air enters the pleural space
during inspiration but cannot escape. This leads to a progressive
buildup of pressure, collapsing the lung on the affected side and
pushing the mediastinum (including the trachea) to the
contralateral (opposite) side.
9
A patient presents with an intracerebral hemorrhage adjacent to a lesion
described as a tangle of numerous tortuous vessels. This description is most
consistent with:
A) Cavernous hemangioma
B) Berry aneurysm
C) Arteriovenous malformation (AVM)
D) Charcot-Bouchard microaneurysm
E) Venous angioma
Correct Answer: C) AVM arteriovenous malformation
Rationale: An arteriovenous malformation (AVM) is a congenital
anomaly consisting of a direct shunt between arteries and veins,
bypassing the capillary bed. These tangled, tortuous vessels are
prone to rupture and hemorrhage.
COMPLETE QUESTIONS WITH 100% RATED CORRECT
ANSWERS | GET IT A+
1
Which medication is a first-line agent used in the treatment of ulcerative
colitis and Crohn's disease?
A) Metronidazole
B) Sulfasalazine
C) Prednisone
D) Azathioprine
E) Infliximab
Correct Answer: B) sulfasalazine
Rationale: Sulfasalazine is an aminosalicylate commonly used as a
first-line treatment for mild to moderate inflammatory bowel
disease (IBD), including ulcerative colitis and Crohn's disease, due
to its anti-inflammatory properties in the gut.
2
The characteristic pulmonary effects observed in patients with Cystic Fibrosis
(CF) include:
A) Restrictive lung disease and pleural effusions.
B) Chronic bronchitis and bronchiectasis.
C) Pulmonary hypertension and right heart failure.
D) Acute pneumonia and ARDS.
E) Obstructive sleep apnea and central hypoventilation.
Correct Answer: B) chronic bronchitis and bronchiectasis
Rationale: Cystic Fibrosis is characterized by the production of thick,
sticky mucus, which leads to chronic airway obstruction, recurrent
infections, chronic bronchitis, and ultimately bronchiectasis
(permanent dilation of bronchi).
3
Osteoporosis primarily affects which type of bone within the skeletal system?
A) Cortical bone mass only.
,B) Trabecular (spongy) bone mass primarily.
C) Both cortical and trabecular bone equally.
D) Bone marrow density.
E) Only the compact bone of long bones.
Correct Answer: B) trabecular bone mass loss
Rationale: Osteoporosis predominantly leads to the loss of trabecular
(spongy) bone mass, which is metabolically more active and thus
more susceptible to demineralization, although cortical bone is also
affected.
4
A patient is prescribed Imipramine. Which class of antidepressants does this
drug belong to, and what are its potential serious side effects ("Tri-Cs")?
A) SSRI; Serotonin Syndrome, Sexual Dysfunction, Stomach upset.
B) SNRI; Seizures, Nausea, Insomnia.
C) TCA; Convulsions, Coma, Cardiotoxicity.
D) MAOI; Hypertensive Crisis, Hepatotoxicity.
E) Atypical Antidepressant; Weight gain, Sedation.
Correct Answer: C) TCA; Convulsions, Coma, Cardiotoxicity
Rationale: Imipramine is a tricyclic antidepressant (TCA). Overdose or
high doses can lead to the "Tri-Cs" of convulsions, coma, and
cardiotoxicity (e.g., arrhythmias, QTc prolongation), as well as
significant anticholinergic effects.
5
Which phenomenon describes the manifestation of a visceral (organ) disease
as a finding in the corresponding somatic (musculoskeletal) tissue?
A) Somatic dysfunction.
B) Viscerosomatic reflex.
C) Somatosomatic reflex.
D) Viscerovisceral reflex.
E) Referred pain.
,Correct Answer: B) viscerosomatic
Rationale: A viscerosomatic reflex is a phenomenon where localized
visceral pathology or dysfunction results in a reflex somatic
(musculoskeletal) manifestation, such as muscle spasm, tenderness,
or tissue texture changes in a corresponding dermatome/myotome
segment.
6
Which of the following drugs is a second-generation H1 blocker that typically
causes less sedation compared to first-generation H1 blockers?
A) Ranitidine
B) Cimetidine
C) Loratadine
D) Diphenhydramine
E) Famotidine
Correct Answer: C) loratidine
Rationale: Loratadine is a second-generation H1 blocker that does not
readily cross the blood-brain barrier, resulting in significantly less
sedation compared to first-generation antihistamines like
diphenhydramine.
7
A stool sample reveals cells containing phagocytosed red blood cells (RBCs).
This finding is characteristic of infection with which protozoan parasite?
A) Giardia lamblia
B) Cryptosporidium parvum
C) Entamoeba histolytica
D) Cyclospora cayetanensis
E) Balantidium coli
Correct Answer: C) entaemoba histolytica
Rationale: The presence of red blood cells (RBCs) inside trophozoites
, on a stool examination is a classic diagnostic feature of Entamoeba
histolytica infection, indicating invasive amebiasis.
8
Which type of pneumothorax causes tracheal deviation away from the
affected side?
A) Spontaneous pneumothorax
B) Iatrogenic pneumothorax
C) Open pneumothorax
D) Tension pneumothorax
E) Simple pneumothorax
Correct Answer: D) tension
Rationale: In a tension pneumothorax, air enters the pleural space
during inspiration but cannot escape. This leads to a progressive
buildup of pressure, collapsing the lung on the affected side and
pushing the mediastinum (including the trachea) to the
contralateral (opposite) side.
9
A patient presents with an intracerebral hemorrhage adjacent to a lesion
described as a tangle of numerous tortuous vessels. This description is most
consistent with:
A) Cavernous hemangioma
B) Berry aneurysm
C) Arteriovenous malformation (AVM)
D) Charcot-Bouchard microaneurysm
E) Venous angioma
Correct Answer: C) AVM arteriovenous malformation
Rationale: An arteriovenous malformation (AVM) is a congenital
anomaly consisting of a direct shunt between arteries and veins,
bypassing the capillary bed. These tangled, tortuous vessels are
prone to rupture and hemorrhage.
