ASCP Recall EXAM QUESTIONS AND CORRECT
DETAILED ANSWERS WITH RATIONALES, ALREADY
GRADED A+
Serum calcitonin elevated in - ANSWER -Medullary carcinoma of thryroid
Normal myeloid:erythroid ratio - ANSWER -2:1 to 4:1
Centromere ANA pattern - ANSWER -CREST syndrome
Homogeneous or speckled ANA pattern - ANSWER -SLE
Speckeled ANA pattern - ANSWER -RA or Sjorgen's
Measurement of sodium/chloride in sweat is useful test for - ANSWER -Cystic
Fibrosis
Analytes increased due to delay in centrifugation - ANSWER -AST, ALT,
Potassium, Creatinine
Analytes decreased due to delay in centrifugation - ANSWER -Glucose, ionized
calcium, bicarbonate, folate
Reducing sugars include - ANSWER -Lactose, glucose, ribose
Incorporation of sulfamethoxazole and trimethoprim in culture media enhance
recovery of - ANSWER -Strep. pyogenes
Longer staining times associated with which type of smear - ANSWER -Bone
marrow smear
Dosage associated with homozygous or heterozygous cells - ANSWER -
Homozygous
Confirmatory test for syphilis - ANSWER -FTA-ABS (fluorescent treponemal
antibody absorption test)
VRDL and RPR are utilize which type of methodology - ANSWER -Flocculation
, Mycobacterium species positive for nitrate reduction - ANSWER -Mycobacterium
tuberculosis
Measles (rubella), mumps, polio vaccine deferral time period - ANSWER -2
weeks
Burkitt's lymphoma - ANSWER -8:14 translocation; associated with EBV; "starry
sky" appearance on histology
Hodgkin Lymphoma (HL) - ANSWER -is a malignant lymphoma
Reed Sternberg cells are the hallmark of HL. Enlarged, painless lymph node in the
neck (often the first sign of HL).
A defective clot retraction might be caused by - ANSWER -Lack of defect of
platelet receptor IIb/IIIa
German measles vaccine deferral time period - ANSWER -4 weeks
This protozoa can be routinely cultured - ANSWER -Acanthamoeba spp.
Aspirin prevent synthesis of - ANSWER -Thromboxane A2
Mycobacterium spp whose colonies are photochromogenic - ANSWER -
Mycobacterium kansaii
Burkholderia cepacia - ANSWER -GNB that is motile with polar tufts of flagella
and produces yellow pigment
Oxidase (+)
Pyocyanin (-)
Arginine dihydrolase (-)
Known to cause fulminating lung infections in CF patients
Burkholderia mallei - ANSWER -Glander's disease
forms nodular lesions in the lung tissue and can cause ulcers leading to sepsis and
death.
, Clenched fist cellulitis associated with what organism - ANSWER -Eikenella
corrodens
CEA tumor marker - ANSWER -colorectal cancer
Intestinal amebiasis symptoms - ANSWER -Abdominal cramps
Fever
Diarrhea
Bloody stool
Type of anemia where inability to incorporate iron into protoporphyrin ring -
ANSWER -Sideroblastic anemia
Immunoassay for hCG uses which subunit of hCG - ANSWER -Beta
Parasite typically comes from cat feces - ANSWER -Toxoplasma gondii
This condition made up of small clots made of platelets and large forms of VWF -
ANSWER -TTP (thrombotic thrombocytopenic purpura)
Normal heme contains - ANSWER -Four heme and four globin chains
Detection of MRSA - ANSWER -Zone of <10mm with an oxacillin disk on MH
agar
Molecular tests for mecA gene
Drug of choice for Clostridium difficile and MRSA - ANSWER -Vancomycin
(glycopeptide, inhibit cell wall synthesis)
Drugs of choice for pseudomonas aeruginosa and other aerobes - ANSWER -
Ciprofloxacin, Norfloxacin (quinolines, inhibit nucleic acid synthesis)
Drug of choice for UTI, enteric infections - ANSWER -Sulfamethoxazole
(Sulfonomides, analogue of PABA)
Extended-spectrum beta-lactamases - ANSWER -Enzymes that give bacteria
immunity to both penicillin and cephalosporin antibiotics
, Tiny GN coccobacilli associated with wild boar - ANSWER -Brucella spp.
This condition is associated with oligoclonal band in CSF electrophoresis -
ANSWER -Multiple sclerosis
Cell indicative of kidney disease - ANSWER -Tubular epithelial cells
Species-specific genes for MRSA - ANSWER -16S and 23S ribosomal RNA
genes
DNA gyrase (gyrA)
Superoxide dismutase (sodA)
UA findings associated with nephrotic syndrome - ANSWER -Oval fat bodies
Fatty and waxy casts
Renal tubular epithelial cells
Heavy proteinuria
Foamy appearance
Follow up tests for speckled ANA patterns - ANSWER -Smith antibodies
SS-A/SS-b+ antibodies
Microorganism associated with tinea cruris AKA jock itch - ANSWER -
Epidermophyton floccosum
Inactive X-chromosome in the somatic cells of mammalian females that appear as
nuclear appendages - ANSWER -Barr body
Deferral time for terminated pregnancy in the 3rd trimester - ANSWER -6 weeks
Overproduced IgM associated with - ANSWER -Waldenstrom's disease
Common cause of atrophic rhinitis - ANSWER -Klebsiella ozaenae
DETAILED ANSWERS WITH RATIONALES, ALREADY
GRADED A+
Serum calcitonin elevated in - ANSWER -Medullary carcinoma of thryroid
Normal myeloid:erythroid ratio - ANSWER -2:1 to 4:1
Centromere ANA pattern - ANSWER -CREST syndrome
Homogeneous or speckled ANA pattern - ANSWER -SLE
Speckeled ANA pattern - ANSWER -RA or Sjorgen's
Measurement of sodium/chloride in sweat is useful test for - ANSWER -Cystic
Fibrosis
Analytes increased due to delay in centrifugation - ANSWER -AST, ALT,
Potassium, Creatinine
Analytes decreased due to delay in centrifugation - ANSWER -Glucose, ionized
calcium, bicarbonate, folate
Reducing sugars include - ANSWER -Lactose, glucose, ribose
Incorporation of sulfamethoxazole and trimethoprim in culture media enhance
recovery of - ANSWER -Strep. pyogenes
Longer staining times associated with which type of smear - ANSWER -Bone
marrow smear
Dosage associated with homozygous or heterozygous cells - ANSWER -
Homozygous
Confirmatory test for syphilis - ANSWER -FTA-ABS (fluorescent treponemal
antibody absorption test)
VRDL and RPR are utilize which type of methodology - ANSWER -Flocculation
, Mycobacterium species positive for nitrate reduction - ANSWER -Mycobacterium
tuberculosis
Measles (rubella), mumps, polio vaccine deferral time period - ANSWER -2
weeks
Burkitt's lymphoma - ANSWER -8:14 translocation; associated with EBV; "starry
sky" appearance on histology
Hodgkin Lymphoma (HL) - ANSWER -is a malignant lymphoma
Reed Sternberg cells are the hallmark of HL. Enlarged, painless lymph node in the
neck (often the first sign of HL).
A defective clot retraction might be caused by - ANSWER -Lack of defect of
platelet receptor IIb/IIIa
German measles vaccine deferral time period - ANSWER -4 weeks
This protozoa can be routinely cultured - ANSWER -Acanthamoeba spp.
Aspirin prevent synthesis of - ANSWER -Thromboxane A2
Mycobacterium spp whose colonies are photochromogenic - ANSWER -
Mycobacterium kansaii
Burkholderia cepacia - ANSWER -GNB that is motile with polar tufts of flagella
and produces yellow pigment
Oxidase (+)
Pyocyanin (-)
Arginine dihydrolase (-)
Known to cause fulminating lung infections in CF patients
Burkholderia mallei - ANSWER -Glander's disease
forms nodular lesions in the lung tissue and can cause ulcers leading to sepsis and
death.
, Clenched fist cellulitis associated with what organism - ANSWER -Eikenella
corrodens
CEA tumor marker - ANSWER -colorectal cancer
Intestinal amebiasis symptoms - ANSWER -Abdominal cramps
Fever
Diarrhea
Bloody stool
Type of anemia where inability to incorporate iron into protoporphyrin ring -
ANSWER -Sideroblastic anemia
Immunoassay for hCG uses which subunit of hCG - ANSWER -Beta
Parasite typically comes from cat feces - ANSWER -Toxoplasma gondii
This condition made up of small clots made of platelets and large forms of VWF -
ANSWER -TTP (thrombotic thrombocytopenic purpura)
Normal heme contains - ANSWER -Four heme and four globin chains
Detection of MRSA - ANSWER -Zone of <10mm with an oxacillin disk on MH
agar
Molecular tests for mecA gene
Drug of choice for Clostridium difficile and MRSA - ANSWER -Vancomycin
(glycopeptide, inhibit cell wall synthesis)
Drugs of choice for pseudomonas aeruginosa and other aerobes - ANSWER -
Ciprofloxacin, Norfloxacin (quinolines, inhibit nucleic acid synthesis)
Drug of choice for UTI, enteric infections - ANSWER -Sulfamethoxazole
(Sulfonomides, analogue of PABA)
Extended-spectrum beta-lactamases - ANSWER -Enzymes that give bacteria
immunity to both penicillin and cephalosporin antibiotics
, Tiny GN coccobacilli associated with wild boar - ANSWER -Brucella spp.
This condition is associated with oligoclonal band in CSF electrophoresis -
ANSWER -Multiple sclerosis
Cell indicative of kidney disease - ANSWER -Tubular epithelial cells
Species-specific genes for MRSA - ANSWER -16S and 23S ribosomal RNA
genes
DNA gyrase (gyrA)
Superoxide dismutase (sodA)
UA findings associated with nephrotic syndrome - ANSWER -Oval fat bodies
Fatty and waxy casts
Renal tubular epithelial cells
Heavy proteinuria
Foamy appearance
Follow up tests for speckled ANA patterns - ANSWER -Smith antibodies
SS-A/SS-b+ antibodies
Microorganism associated with tinea cruris AKA jock itch - ANSWER -
Epidermophyton floccosum
Inactive X-chromosome in the somatic cells of mammalian females that appear as
nuclear appendages - ANSWER -Barr body
Deferral time for terminated pregnancy in the 3rd trimester - ANSWER -6 weeks
Overproduced IgM associated with - ANSWER -Waldenstrom's disease
Common cause of atrophic rhinitis - ANSWER -Klebsiella ozaenae
