infarction
, Introducti
on:
•Definition: Necrosis of heart muscle due to
prolonged ischemia.
•Common cause: Atherosclerotic plaque rupture
→ thrombus formation.
•Major form of ischemic heart disease.
, Etiology and Risk Factors
•Atherosclerosis (most common)
•Coronary artery thrombosis or embolism
•Vasospasm (e.g., cocaine use)
•Risk factors:
o Hypertension, diabetes mellitus
o Smoking, obesity, sedentary lifestyle
o Hyperlipidemia
o Family history