1.NS is a 32-year-old female who had been sick with a cold virus for 10 days. She states that
she had flu symptoms of cough, sore throat, and fatigue. It has been 3 weeks since the
cold, and she continues to be fatigued and finds it hard to get enough energy to do things.
NS says she has noted that she has been bruising easily. She hit her arm accidentally on
the edge of a counter, and now she has a large bruise. She has also noted little purple
spots all over her hands and chest. On examination it is noted that she does have a large
bruise on her right arm and petechiae and purpura over her chest and hands. Lab work
comes back with a platelet count of 40,000mm3.
NS has been diagnosed with immune thrombocytopenic purpura (ITP). Which
of the following is not true about ITP?
Answer It is commonly caused by drugs or toxins
2.Which of the following would you expect to see in a patient with ITP? Select all that apply.
Answer petechiae
epistaxis
hematuria
menorrhagia
3.Treatment for ITP typically includes
Answer glucocorticoids
splenectomy for severe cases
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, PATHO CASE STUDY 6 GUIDE
4.A 63-year-old woman with diabetes notes that she has a general feeling of tiredness and
a loss of appetite. For several months, while on her daily 2-mile walks, she has heard her
heartbeat in her ears as a whooshing sound. Very knowledgeable about her disease and
compliant with diet and medications, she waits until she sees her endocrinologist for her
yearly examination. In the office, she explains her symptoms, and the physician collects
a CBC in addition to normal diabetic laboratory tests. The results indicate an anemia, and
she is referred to a hematologist. The hematologist reviews her laboratory findings and
begins to explain her diagnosis of megaloblastic anemia.
Further testing indicates that the woman suffers from a vitamin B12 deficiency or PA. This
condition is often associated with:
Answer Chronic gastritis
5.The woman is treated with replacement cobalamin (vitamin B12) over several weeks until
the deficiency is corrected. Monthly injections for the remainder of the woman's life are
explained, and she acknowledges the importance of treatment. One year later, the
hematologist sees the woman for follow-up laboratory testing. The woman again
complains of fatigue. Part of her health screening indicates that she has elevated serum
iron and ferritin levels. Confused, the hematologist reviews her medications. She states
that she has been taking several iron supplements and a multivitamin with iron daily after
reading online that anemia should be treated with iron administration. Discussion with
her friends further convinced her that iron was the treatment of choice for anemia. The
physician again explains the patient's initial diagnosis and now informs the woman that
she additionally suffers from secondary iron overload.
The treatment for iron overload is:
Answer Phlebotomy
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