NURS6630 ///NURS 6630
PSYCHOPHARMACOLOGY MIDTERM EXAM 2
LATEST 2025/2026 QUESTIONS and ANSWERS
GRADED A+
Six common side effects of SNRIs include: - CORRECT ANSWER-Insomnia,
nausea, sexual dysfunction, hypertension, sweating, headaches
Severe side effect of SNRIs in children/adolescents under age 25 years old: -
CORRECT ANSWER-suicidal ideation
,Life threatening adverse effect of SNRIs, especially when used in combination
with other serotonergic drugs: - CORRECT ANSWER-Serotonin Syndrome
This SNRI is an inhibitor of Cytochrome P450 enzymes: - CORRECT ANSWER-
venlafaxine
This SNRI is hepatotoxic: - CORRECT ANSWER-duloxetine
Serotonin regulates - CORRECT ANSWER-Mood, emotion, feeding, and
reproductive behavior
This class of antidepressants binds to presynaptic SERT and inhibits them from
reuptake of serotonin to increase levels in the synaptic cleft to bind with
postsysnaptic 5HT2 receptors - CORRECT ANSWER-SSRIs
First line therapy for MDD due to milder side effect profiles - CORRECT
ANSWER-SSRIs
Six Common SSRIs - CORRECT ANSWER-citalopram, escitalopram, fluoxetine,
fluvoxamine, sertraline, paroxetine
Onset of therapeutic benefit from SSRIs - CORRECT ANSWER-4-6 weeks
In addition to MDD, SSRIs also treat - CORRECT ANSWER-Chronic Anxiety,
PTSD, OCD, and eating disorders (bulimia)
, Five Common side effects of SSRIs include - CORRECT ANSWER-Anxiety,
insomnia, GI distress, sexual dysfunction (ED), SIADH
Severe side effect of SSRIs in children/adolescents under age 25 years old -
CORRECT ANSWER-suicidal ideation
Life threatening adverse effect of SSRIs, especially when used in combination with
other serotonergic drugs (SNRIs, TCAs, MAOIs, etc.) - CORRECT ANSWER-
Serotonin Syndrome
Excess accumulation of serotonin resulting in overstimulation of the nervous
system - CORRECT ANSWER-Serotonin Syndrome
Seven symptoms of Serotonin Syndrome - CORRECT ANSWER-Flushing,
hyperthermia, agitation, muscle rigidity, seizure, coma, HYPERreflexia
The treatment for serotonin syndrome - CORRECT ANSWER-Cyproheptadine
(5-HT2 receptor antagonist)
Cyproheptadine treats serotonin syndrome by - CORRECT ANSWER-blocking 5-
HT2 receptors (serotonin antagonist)
When SSRIs or SNRIs are stopped abruptly, common symptoms of withdrawal
include - CORRECT ANSWER-Irritability, headaches, and insomnia
Medicine specific side effect of citalopram - CORRECT ANSWER-Prolonged QT
interval (normal=0.4.-0.44 seconds)
PSYCHOPHARMACOLOGY MIDTERM EXAM 2
LATEST 2025/2026 QUESTIONS and ANSWERS
GRADED A+
Six common side effects of SNRIs include: - CORRECT ANSWER-Insomnia,
nausea, sexual dysfunction, hypertension, sweating, headaches
Severe side effect of SNRIs in children/adolescents under age 25 years old: -
CORRECT ANSWER-suicidal ideation
,Life threatening adverse effect of SNRIs, especially when used in combination
with other serotonergic drugs: - CORRECT ANSWER-Serotonin Syndrome
This SNRI is an inhibitor of Cytochrome P450 enzymes: - CORRECT ANSWER-
venlafaxine
This SNRI is hepatotoxic: - CORRECT ANSWER-duloxetine
Serotonin regulates - CORRECT ANSWER-Mood, emotion, feeding, and
reproductive behavior
This class of antidepressants binds to presynaptic SERT and inhibits them from
reuptake of serotonin to increase levels in the synaptic cleft to bind with
postsysnaptic 5HT2 receptors - CORRECT ANSWER-SSRIs
First line therapy for MDD due to milder side effect profiles - CORRECT
ANSWER-SSRIs
Six Common SSRIs - CORRECT ANSWER-citalopram, escitalopram, fluoxetine,
fluvoxamine, sertraline, paroxetine
Onset of therapeutic benefit from SSRIs - CORRECT ANSWER-4-6 weeks
In addition to MDD, SSRIs also treat - CORRECT ANSWER-Chronic Anxiety,
PTSD, OCD, and eating disorders (bulimia)
, Five Common side effects of SSRIs include - CORRECT ANSWER-Anxiety,
insomnia, GI distress, sexual dysfunction (ED), SIADH
Severe side effect of SSRIs in children/adolescents under age 25 years old -
CORRECT ANSWER-suicidal ideation
Life threatening adverse effect of SSRIs, especially when used in combination with
other serotonergic drugs (SNRIs, TCAs, MAOIs, etc.) - CORRECT ANSWER-
Serotonin Syndrome
Excess accumulation of serotonin resulting in overstimulation of the nervous
system - CORRECT ANSWER-Serotonin Syndrome
Seven symptoms of Serotonin Syndrome - CORRECT ANSWER-Flushing,
hyperthermia, agitation, muscle rigidity, seizure, coma, HYPERreflexia
The treatment for serotonin syndrome - CORRECT ANSWER-Cyproheptadine
(5-HT2 receptor antagonist)
Cyproheptadine treats serotonin syndrome by - CORRECT ANSWER-blocking 5-
HT2 receptors (serotonin antagonist)
When SSRIs or SNRIs are stopped abruptly, common symptoms of withdrawal
include - CORRECT ANSWER-Irritability, headaches, and insomnia
Medicine specific side effect of citalopram - CORRECT ANSWER-Prolonged QT
interval (normal=0.4.-0.44 seconds)
