chapter 1 Drug action: Pharmaceutic, Pharmacokinetic and
Pharmacodynamic Phases
1. Pharmaceutic- drug becomes a solution so that it
Differentiate the three can cross the biological membrane.
phases of drug action 2. Pharmacokinetic- the process of drug movement to achieve drug
action
3. Pharmacodynamic- biological or physiologic response result.
Discuss the two processes Disintegration- the breakdown of a tablet into smaller particles
that occur before tablets Dissolutons- dissolving of the smaller particles in the GI fluid befor
are absorbed into the body absorption
absorption- the movement of drug particles from the GI tract
to body fluids by passive absorption, active absorption, or
Describe the four pincytosis.
processes of distribution-process by which the drug becomes available to
pharmacokinetics body fluids and body tissues. influnced by blood flow
metabolism
(biotransformation)
excretion (elimination).
The route of injection site that Intramuscular (Deltoids)
will allow medication to take
the quickest effect.
which site has the slowest Subcutaneous tissue. This is due to the area having fewer blood
absorption rate and why? vessels
requires a carrier such as an enzyme or protein to move the
Active absorption
drug against a concentration gradient
Adverse reaction More severe side effect
Agonists drugs that produce a response; tells a drug to do something
Antagonists drugs that block a response
, Percentage (Amount) of the administered drug dose that
Bioavailability
reaches the systemic circulation
Pharmacodynamic Phases
1. Pharmaceutic- drug becomes a solution so that it
Differentiate the three can cross the biological membrane.
phases of drug action 2. Pharmacokinetic- the process of drug movement to achieve drug
action
3. Pharmacodynamic- biological or physiologic response result.
Discuss the two processes Disintegration- the breakdown of a tablet into smaller particles
that occur before tablets Dissolutons- dissolving of the smaller particles in the GI fluid befor
are absorbed into the body absorption
absorption- the movement of drug particles from the GI tract
to body fluids by passive absorption, active absorption, or
Describe the four pincytosis.
processes of distribution-process by which the drug becomes available to
pharmacokinetics body fluids and body tissues. influnced by blood flow
metabolism
(biotransformation)
excretion (elimination).
The route of injection site that Intramuscular (Deltoids)
will allow medication to take
the quickest effect.
which site has the slowest Subcutaneous tissue. This is due to the area having fewer blood
absorption rate and why? vessels
requires a carrier such as an enzyme or protein to move the
Active absorption
drug against a concentration gradient
Adverse reaction More severe side effect
Agonists drugs that produce a response; tells a drug to do something
Antagonists drugs that block a response
, Percentage (Amount) of the administered drug dose that
Bioavailability
reaches the systemic circulation
