Georgia College & State University Cardiovascular
Pharmacology 2 Questions With Complete Solutions
Why is morphine used in pain control in ACS?
decreases oxygen demand through vasodilation
What are beta blockers used in the treatment of ACS?
decrease the incidence of ventricular arrhythmias and limit
infarct size by decreasing oxygen demand
What are ACE inhibitors used in ACS treatment?
decrease myocardial afterload by vasodilation
How long are anticoagulants used in ACS treatment?
until ruptured plaque has completely resolved
Why is reperfusion therapy used in the treatment of ACS?
to restore adequate coronary perfusion
What are the three reperfusion therapies?
percutaneous coronary intervention, coronary artery bypass
grafting, and thrombolytic therapy
Why is thrombolytic therapy contraindicated in NSTEMI?
evidence shoes that is results in worse outcomes
What actions do nitroglycerin cause?
vasodilation to increase bloodflow to the heart, decrease
workload of the heart, and decrease cardiac oxygen demand
,What is the indication for nitroglycerin?
cardiac related chest pain
When would nitroglycerin be contraindicated?
SBP<90, three doses already, and ED medication within 24
hours
What routes can nitroglycerin be administered?
sublingual tablet or spray
What is the dose of nitroglycerin?
0.4 mg tablet or spray every 3-5 min until pain resolves; up to 3
doses
What is the action of aspirin?
prevents platelet aggregation (clumping together)
What is an indication for aspirin?
cardiac related chest pain
What are the contraindications for aspirin?
known allergy, already dosed
What route is aspirin given?
oral
What is the dose of aspirin?
325 mg tablet or chewable baby aspirin equivalent
What is the action of morphine?
, analgesic and sedative that causes some vasodilation, reducing
venous return and reducing myocardial oxygen demand
What is the indication for morphine in ACS?
moderate to severe chest pain, and to reduce venous return in
pulmonary edema
What contraindications to morphine?
allergy, hypotension, and volume depletion
What respiratory illnesses would be a contraindication to
morphine because of the resp depression?
acute asthma, COPD, resp depression, or pulmonary edema
from chemical inhalation
What affect do beta blockers have on the body that helps treat
ACS?
reduce oxygen demand and ventricular wall tension, decrease
mortality and may reduce mechanical complications of MI
What is a mechanical complication of MI?
rupture of the papillary muscle, left ventricular free wall, and
ventricular septum
What are contraindications to beta blockers?
SBP < 90, cardiogenic shock, bradycardia, 2nd/3rd degree heart
block, asthma/emphysema, PVD, uncompensated HF
What are nonpharmacologic management strategies for angina?
smoking cessation, physical activity, cardiac rehab,
weight/stress management, limit alcohol intake
Pharmacology 2 Questions With Complete Solutions
Why is morphine used in pain control in ACS?
decreases oxygen demand through vasodilation
What are beta blockers used in the treatment of ACS?
decrease the incidence of ventricular arrhythmias and limit
infarct size by decreasing oxygen demand
What are ACE inhibitors used in ACS treatment?
decrease myocardial afterload by vasodilation
How long are anticoagulants used in ACS treatment?
until ruptured plaque has completely resolved
Why is reperfusion therapy used in the treatment of ACS?
to restore adequate coronary perfusion
What are the three reperfusion therapies?
percutaneous coronary intervention, coronary artery bypass
grafting, and thrombolytic therapy
Why is thrombolytic therapy contraindicated in NSTEMI?
evidence shoes that is results in worse outcomes
What actions do nitroglycerin cause?
vasodilation to increase bloodflow to the heart, decrease
workload of the heart, and decrease cardiac oxygen demand
,What is the indication for nitroglycerin?
cardiac related chest pain
When would nitroglycerin be contraindicated?
SBP<90, three doses already, and ED medication within 24
hours
What routes can nitroglycerin be administered?
sublingual tablet or spray
What is the dose of nitroglycerin?
0.4 mg tablet or spray every 3-5 min until pain resolves; up to 3
doses
What is the action of aspirin?
prevents platelet aggregation (clumping together)
What is an indication for aspirin?
cardiac related chest pain
What are the contraindications for aspirin?
known allergy, already dosed
What route is aspirin given?
oral
What is the dose of aspirin?
325 mg tablet or chewable baby aspirin equivalent
What is the action of morphine?
, analgesic and sedative that causes some vasodilation, reducing
venous return and reducing myocardial oxygen demand
What is the indication for morphine in ACS?
moderate to severe chest pain, and to reduce venous return in
pulmonary edema
What contraindications to morphine?
allergy, hypotension, and volume depletion
What respiratory illnesses would be a contraindication to
morphine because of the resp depression?
acute asthma, COPD, resp depression, or pulmonary edema
from chemical inhalation
What affect do beta blockers have on the body that helps treat
ACS?
reduce oxygen demand and ventricular wall tension, decrease
mortality and may reduce mechanical complications of MI
What is a mechanical complication of MI?
rupture of the papillary muscle, left ventricular free wall, and
ventricular septum
What are contraindications to beta blockers?
SBP < 90, cardiogenic shock, bradycardia, 2nd/3rd degree heart
block, asthma/emphysema, PVD, uncompensated HF
What are nonpharmacologic management strategies for angina?
smoking cessation, physical activity, cardiac rehab,
weight/stress management, limit alcohol intake
