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1. Cell wall synthesis inhibitors - ANSWER Beta-lactams and glycopeptides
2. Beta lactams - ANSWER penicillin and cephalosporins
3. Cephalexin and cephalothin are in what generation of cephalosporin? -
ANSWER 1st generation GP
4. Cefoxitin and cefotetan are what generation of cephalosporin? - ANSWER
2nd generation GP and GN
5. Cefoxatime, cetriaxone and ceftazidime are what generation of
cephalosporin? - ANSWER 3rd generation GN
6. What generation of cephalosporin penetrates CSF? - ANSWER third
generation
,7. Cefepime is what generation of cephalosporin? - ANSWER fourth
generation more GN and many GP
8. What generation of cephalosporin has beta lactamase stability? - ANSWER
fourth generation
9. What generation of cephalosporin has ceftaroline? - ANSWER fifth
generation
10.What generation of cephalosporin has active vs mrsa? - ANSWER 5th
generation
11.glycopeptides are gp only and involve the antibiotics - ANSWER
vancomycin and teicoplanin
12.plasma membrane damage mechanism involves - ANSWER
polypeptides
13.antibiotics under plasma membrane inhibitors are - ANSWER polymyxin
and colistin
14.Type of inhibitor that contains these groups of antibiotics
tetracycline
macrolide
chloromphenicol
, lincosamide
aminoglycoside
ketolide - ANSWER protein synthesis
15.Macrolides - ANSWER erythromycin and azithromycin
16.Lincosomides - ANSWER clindamycin
17.aminoglycosides - ANSWER Gentamicin
18.inhibitor that involves
quinolones
metronidazole
rifampin - ANSWER nucleic acid synthesis inhibition
19.inhibitor that involves sulfonamide and trimethoprim - ANSWER metabolic
pathway
20.is a resistance that involved a horizontal transfer of a R plasmid - ANSWER
acquired
21.what type of bacteria produces beta lactamase - ANSWER Gram
negative
, 22.decreased intracellular drug accumulation - ANSWER efflux pumps
23.altered metabolic pathway involves... - ANSWER folic acid
24.AST standards - ANSWER 0.5 McFarland standard= 1.5 x 10^8 cfu/ml
25.qualitative AST - ANSWER disk diffusion
26.larger the zone the _________ MIC - ANSWER smaller
27.gradient strip and quantitative - ANSWER ETEST
28.in this test the point where zone of inhibition intersects the strip is the MIC
- ANSWER etest
29.Quality control organisms - ANSWER S. aureus
E.coli
P. aeruginosa
30.quality control is recommended each day but reduced to 1 day per week if
acceptable results for each antimicrobial obtained for - ANSWER 30
days