Rated A
Watson and Crick - -discovered the amounts of bases
structure of DNA as double helix in 1953
double helix - -twisted-ladder shape of
DNA replication - -process by which DNA DNA, formed by two nucleotide strands twisted
is copied in a cell before a cell divides by mitosis, around each other
meiosis, or binary fission
antiparallel - -Parallel, but running in
Griffith - -1928, Accidentally discovered opposite directions. The 5' end of one strand of
transformation by combining a heat killed virulent DNA aligns with the 3' end of the other strand in a
strain of bacteria with a live non virulent strain double-helix.
while studying pneumonia.
semiconservative model - -Type of DNA
transformation - -(genetics) modification of replication in which the replicated double helix
a cell or bacterium by the uptake and consists of one old strand, derived from the old
incorporation of exogenous DNA molecule, and one newly made strand.
Avery - -1944 - experiments on the strains conservative model - -The two parental
of a cell that led to the discovery that DNA was strands reassociate after acting as templates for
the transforming factor not the protein new strands, thus restoring the parental double
helix
bacteriophage - -a virus that infects
bacteria dispersive model - -each strand of both
daughter molecules contains a mixture of old and
newly synthesized DNA
virus - -an infectious particle made only of
a strand of DNA or RNA surrounded by a protein
coat origin of replication - -Site where the
replication of a DNA molecule begins, consisting
of a specific sequence of nucleotides.
Hershey and Chase - -Identified DNA to be
genetic material through experiments with
bacteriophages replication fork - -A Y-shaped region on a
replicating DNA molecule where new strands are
growing.
Chargaff's rules - -1. number of adenines =
number of thymines
number of cytosines = number of guanines helicase - -an enzyme that untwists the
2. species differ in the number of relative double helix at the replication forks, separating
the two parental strands and making them
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