Page |1
NUR 521 ADV PHARM EXAM 3 Newest 2025/2026 NEWEST
ACTUAL EXAM WITH COMPLETE QUESTIONS AND
VERIFIED ANSWERS |ALREADY GRADED A+|
What education do you want to provide to your pt taking
clindamycin? - ANSWER-notify the provider of any significant
diarrhea (>5 watery stools a day)
What is the BBW for Clindamycin? - ANSWER-Colitis (C. diff)
what is the MOA of linezolid (Zyvox) and what does it treat? -
ANSWER-inhibits protein synthesis
- VRE and MRSA (multidrug resistance gram-positive pathogens)
- streptococcus and S.aureus (cillin-resistant strains)
Generally Linezolid is reserved for infections caused by
___________ and _________, why? - ANSWER-VRE and MRSA.
The risk for hematologic (>2wks) and neurologic(>4wks) toxicity
increase w/ prolonged therapy
, Page |2
What meds are CI to take if taking Linezolid? - ANSWER-SSRI
and MAOI (within 2wk period)
- MAOI (zyvox contains phenylalanine) = htn crisis
- SSRI = serotonin syndrome
(Think how prisoners are depressed and walk in a LINE but aren't
allowed to take antidepressants)
What are the AE of Linezolid? - ANSWER-- Reversible
myelosuppresion- anemia, leukopenia, thrombocytopenia,
pancytopenia
(depression if ya know what i mean)
- peripheral neuropathy w/ prolonged use (rare and can be
irreversible..told you to only use it for VRE or MRSA)
- reversible optic neuropathy w/ prolonged use
Gentamicin MOA and what bacteria does it treat? - ANSWER-
Inhibit protein synthesis
Gram - bacilli (aerobic)
- e.coli
, Page |3
- klebsiella
- serratia marcescens
- proteus mirabilis
- PSUEDOMONAS AERUGINOSA
How do aminoglycosides cause nephrotoxicity and ototoxicity? -
ANSWER-- they bind tightly to the renal tissue achieving levels
50x higher than levels in the serum causing nephrotoxicity
- penetrate readily to the perilymph and endolymph of the inner
ears and can thereby cause ototoxicity
What are the AE of gentamicin? - ANSWER-nephrotoxicity
ototoxicity
GENTly put the KIDs (nephrotoxicity) down to bed and don't let
them HEAR (ototoxicity) you
What is are the CI for taking Gentamicin? - ANSWER-Renal
disease and hearing impairment
NUR 521 ADV PHARM EXAM 3 Newest 2025/2026 NEWEST
ACTUAL EXAM WITH COMPLETE QUESTIONS AND
VERIFIED ANSWERS |ALREADY GRADED A+|
What education do you want to provide to your pt taking
clindamycin? - ANSWER-notify the provider of any significant
diarrhea (>5 watery stools a day)
What is the BBW for Clindamycin? - ANSWER-Colitis (C. diff)
what is the MOA of linezolid (Zyvox) and what does it treat? -
ANSWER-inhibits protein synthesis
- VRE and MRSA (multidrug resistance gram-positive pathogens)
- streptococcus and S.aureus (cillin-resistant strains)
Generally Linezolid is reserved for infections caused by
___________ and _________, why? - ANSWER-VRE and MRSA.
The risk for hematologic (>2wks) and neurologic(>4wks) toxicity
increase w/ prolonged therapy
, Page |2
What meds are CI to take if taking Linezolid? - ANSWER-SSRI
and MAOI (within 2wk period)
- MAOI (zyvox contains phenylalanine) = htn crisis
- SSRI = serotonin syndrome
(Think how prisoners are depressed and walk in a LINE but aren't
allowed to take antidepressants)
What are the AE of Linezolid? - ANSWER-- Reversible
myelosuppresion- anemia, leukopenia, thrombocytopenia,
pancytopenia
(depression if ya know what i mean)
- peripheral neuropathy w/ prolonged use (rare and can be
irreversible..told you to only use it for VRE or MRSA)
- reversible optic neuropathy w/ prolonged use
Gentamicin MOA and what bacteria does it treat? - ANSWER-
Inhibit protein synthesis
Gram - bacilli (aerobic)
- e.coli
, Page |3
- klebsiella
- serratia marcescens
- proteus mirabilis
- PSUEDOMONAS AERUGINOSA
How do aminoglycosides cause nephrotoxicity and ototoxicity? -
ANSWER-- they bind tightly to the renal tissue achieving levels
50x higher than levels in the serum causing nephrotoxicity
- penetrate readily to the perilymph and endolymph of the inner
ears and can thereby cause ototoxicity
What are the AE of gentamicin? - ANSWER-nephrotoxicity
ototoxicity
GENTly put the KIDs (nephrotoxicity) down to bed and don't let
them HEAR (ototoxicity) you
What is are the CI for taking Gentamicin? - ANSWER-Renal
disease and hearing impairment
