CPHON CHEMO RENEWAL EXAM LATEST 2025-2026
ACTUAL EXAM 100 QUESTIONS AND CORRECT
ANSWERS
Overview
The CPHON Renewal Exam Study Guide 2025–2026 mirrors the structure and rigor of the
official ONCC renewal exam, offering realistic questions and in-depth explanations to enhance
comprehension and clinical reasoning. It covers all major domains, including chemotherapy
safety, pediatric cancer treatment protocols, symptom management, hematologic disorders,
patient and family education, and interprofessional collaboration. Updated to reflect current
pediatric oncology standards, this guide ensures readiness for certification renewal and continued
excellence in clinical practice.
Key Features
✅ 100 Verified Exam Questions with Correct, Detailed Answers
✅ Aligned with ONCC 2025–2026 CPHON Renewal Standards
✅ Covers All Core Topics — Pediatric Oncology, Chemotherapy, and Safety
✅ Realistic Exam Format for Effective Test Practice
✅ Developed by Certified Pediatric Oncology Nursing Experts
Purpose
• To prepare oncology nurses for success on the CPHON Renewal Exam
• To reinforce clinical knowledge and pediatric oncology best practices
• To support professional development and ongoing certification compliance
Recommended For
• Certified Pediatric Hematology-Oncology Nurses (CPHON®) renewing certification
• Pediatric oncology and chemotherapy nurses seeking updated review materials
• Nurse educators and trainers providing ONCC renewal prep resources
• Healthcare professionals specializing in pediatric hematology and oncology care
,✅ Your Complete CPHON Renewal Study Resource
With 100 verified, detailed, and up-to-date questions, the CPHON Chemotherapy Renewal
Exam Study Guide 2025–2026 is your most accurate and reliable tool for mastering pediatric
oncology nursing principles — and maintaining your CPHON certification with confidence.
A nurse is administering an IV chemotherapy agent and the IV tubing leaks, causing a spill. Who is
responsible for containing the chemo spill?
A. Pharmacy
B. Nursing
C. Nursing assistants
D. Housekeeping - ANSWER-B
The federal organization that requires all health care facilities to maintain and follow policies or clinical
guidelines pertaining to the safe handling of chemo agents is:
A. AMA
B. FDA
C. OSHA
D. The Joint Commission - ANSWER-C
As you are hanging your patient's IV chemo bag, the bag accidentally disconnects from the tubing and
the chemo spills down the IV pole and onto the floor. What is your first action?
A. Restrict access to the spill area
B. Obtain a chemo spill kit
C. Document the spill
D. Fill out an incident report - ANSWER-A
, When administering an IV injection of __________, it is expected that the nurse knows where the
emergency medications are kept in their area and has appropriate emergency equipment at the
bedside.
A. Methotrexate
B. Busulfan
C. Cytarabine
D. Bleomycin - ANSWER-D
When providing patient education on taking Mercaptopurine or Thioguanine by mouth, which of the
following instructions would you include?
A. Take on a full stomach, shortly after a meal
B. Take with citrus fruits to increase absorption
C. Take on an empty stomach, 1 hour before or 2 hours after a meal
D. Take with dairy products - ANSWER-C
In which location would you most likely expect a patient to complain of pain after receiving Vincristine?
A. Jaw
B. Eye
C. Throat
D. Spine - ANSWER-A
Frequent bath, avoidance of creams, emollients, and occlusive dressings are all examples of skin care
precautions one must consider when administering:
A. Topetecan
ACTUAL EXAM 100 QUESTIONS AND CORRECT
ANSWERS
Overview
The CPHON Renewal Exam Study Guide 2025–2026 mirrors the structure and rigor of the
official ONCC renewal exam, offering realistic questions and in-depth explanations to enhance
comprehension and clinical reasoning. It covers all major domains, including chemotherapy
safety, pediatric cancer treatment protocols, symptom management, hematologic disorders,
patient and family education, and interprofessional collaboration. Updated to reflect current
pediatric oncology standards, this guide ensures readiness for certification renewal and continued
excellence in clinical practice.
Key Features
✅ 100 Verified Exam Questions with Correct, Detailed Answers
✅ Aligned with ONCC 2025–2026 CPHON Renewal Standards
✅ Covers All Core Topics — Pediatric Oncology, Chemotherapy, and Safety
✅ Realistic Exam Format for Effective Test Practice
✅ Developed by Certified Pediatric Oncology Nursing Experts
Purpose
• To prepare oncology nurses for success on the CPHON Renewal Exam
• To reinforce clinical knowledge and pediatric oncology best practices
• To support professional development and ongoing certification compliance
Recommended For
• Certified Pediatric Hematology-Oncology Nurses (CPHON®) renewing certification
• Pediatric oncology and chemotherapy nurses seeking updated review materials
• Nurse educators and trainers providing ONCC renewal prep resources
• Healthcare professionals specializing in pediatric hematology and oncology care
,✅ Your Complete CPHON Renewal Study Resource
With 100 verified, detailed, and up-to-date questions, the CPHON Chemotherapy Renewal
Exam Study Guide 2025–2026 is your most accurate and reliable tool for mastering pediatric
oncology nursing principles — and maintaining your CPHON certification with confidence.
A nurse is administering an IV chemotherapy agent and the IV tubing leaks, causing a spill. Who is
responsible for containing the chemo spill?
A. Pharmacy
B. Nursing
C. Nursing assistants
D. Housekeeping - ANSWER-B
The federal organization that requires all health care facilities to maintain and follow policies or clinical
guidelines pertaining to the safe handling of chemo agents is:
A. AMA
B. FDA
C. OSHA
D. The Joint Commission - ANSWER-C
As you are hanging your patient's IV chemo bag, the bag accidentally disconnects from the tubing and
the chemo spills down the IV pole and onto the floor. What is your first action?
A. Restrict access to the spill area
B. Obtain a chemo spill kit
C. Document the spill
D. Fill out an incident report - ANSWER-A
, When administering an IV injection of __________, it is expected that the nurse knows where the
emergency medications are kept in their area and has appropriate emergency equipment at the
bedside.
A. Methotrexate
B. Busulfan
C. Cytarabine
D. Bleomycin - ANSWER-D
When providing patient education on taking Mercaptopurine or Thioguanine by mouth, which of the
following instructions would you include?
A. Take on a full stomach, shortly after a meal
B. Take with citrus fruits to increase absorption
C. Take on an empty stomach, 1 hour before or 2 hours after a meal
D. Take with dairy products - ANSWER-C
In which location would you most likely expect a patient to complain of pain after receiving Vincristine?
A. Jaw
B. Eye
C. Throat
D. Spine - ANSWER-A
Frequent bath, avoidance of creams, emollients, and occlusive dressings are all examples of skin care
precautions one must consider when administering:
A. Topetecan
