University 2025–2026 Complete Objective Assessment Exam
with Correct Answers and Detailed Rationales
Introduction:
This document provides the complete and updated set of questions
and correct answers for the WGU D027 Objective Assessment Final
Exam for the academic year 2025–2026. It includes detailed
rationales for every answer, ensuring a thorough understanding of
the material. Topics covered span pharmacology, pathophysiology,
genetics, cardiovascular, endocrine, respiratory, and hematologic
disorders, as well as key concepts from health informatics such as
data governance, interoperability, EHRs, AI in healthcare, and data
security. This comprehensive exam prep is ideal for WGU students
seeking a guaranteed pass and full mastery of course objectives.
Exam Questions and Answers
What is the first line of treatment for uncomplicated otitis media in
pediatric patient without comorbidities? --- correct answer ---
Amoxicillin
How do you test for postural orthostatic tachycardia syndrome? ---
correct answer ---Tilt test
What is Florinef (corticosteroid) used for? --- correct answer ---
Used to treat postural hypotension and adrenal insufficiency.
,What are the side effects of Florinef? --- correct answer ---Nausea,
headache, sleep problems, and mood changes.
What is the off label use for prazosin/minipress (alpha- 1 blocker)?
--- correct answer ---Sleep aid for patients diagnosed with PTSD
Which medications are used to treat myasthenia gravis? --- correct
answer ---Corticosteroids and cholinesterase inhibitors.
Side effects of cholinesterase inhibitors (neostigmine): --- correct
answer ---Excessive salvation, urinary urgency, sweating, spasm,
bradycardia
What is the first line of treatment for uncomplicated hypertension?
--- correct answer ---Hydrochlorothiazide(thiazide diuretic) orally
with lifestyle changes.
What might cause ataxia in a pediatric patient? --- correct answer -
--- Fragile X syndrome
- Prader Willie Syndrome by deletion of chromosome 15 from father
Combined ___________ are contraindicated when breast feeding. ---
correct answer ---Oral contraceptives
,Which antibiotic would you use for treatment of UTI during
pregnancy? --- correct answer ---One-time dose of Fosfomycin and
cephalexin.
NO PENCILLINS
How to treat pediatric UTI with no comorbidities? --- correct
answer ---Trimethoprim/sulfamethoxazole (Bactrim, Septra)
Augmentin
Cephalosporins
Which parent does color blindness come from? --- correct answer --
-X-linked so mother. 50% chance of getting it. Gene OPN1MW on
chromosome 23 is mutated causing color blindness.
What is the first treatment for sickle cell crisis? --- correct answer
---Hydration
Parental care of the newborn with sickle cell anemia: --- correct
answer ---- Infant will be anemic
- Increased risk for infection
- May have spleen or liver damage causing jaundice
- May have crying episodes from pain and swelling of extremities
- Hydrate, administer vaccines, antibiotics when necessary, folic
acid administration, and regular eye exams
, Should you admit or monitor a young athletic patient with
bradycardia? --- correct answer ---Monitor as it is normal.
Which part of the GI tract does Crohn's disease effect? --- correct
answer ---Affects all GI tract and has skip lesions
Which patients have an increased risk of inflammatory bowel
disease? --- correct answer ---Patients with atopic dermatitis and
eczema
What diagnostic labs will be drawn for ulcerative colitis? --- correct
answer ---CBC, CRP, ESR, LFT, electrolyte panel, and ANA
A Japanese male present with hypertension and chronic kidney
disease, which antihypertensive would you give? --- correct answer
---ACE inhibitor or ARB. Next course of action is to reduce amount
of salt in diet.
Which medications are given PRN for anxiety? --- correct answer --
-Benzodiazepines (Diazepam), Vistaril (antihistamine), Seroquel
(antipsychotic effects), SSRIs (Prozac, Paxil, Zoloft), and Wellbutrin
(antidepressant), and Risperidone (side effect is neutropenia)