NR 341 Pharmacology Practice Exam
With Actual 120 Questions & Verified
Answers,Plus Rationales/Expert
Verified For Guaranteed Pass Graded
A+/ 2025/2026 /Latest Update/Instant
Download Pdf
NR 341 Pharmacology Exam
1. Which medication is most commonly used to reverse opioid overdose?
a. Morphine
b. Naloxone
c. Flumazenil
d. Naltrexone
b. Naloxone
Rationale: Naloxone is an opioid antagonist that rapidly reverses respiratory
depression caused by opioid overdose.
2. A nurse is administering digoxin. What is the most important assessment before
giving the dose?
a. Respiratory rate
b. Apical pulse
c. Oxygen saturation
d. Blood glucose
b. Apical pulse
Rationale: Digoxin can cause bradycardia. The apical pulse should be checked for 1
full minute; hold if less than 60 bpm.
3. Which drug class is first-line treatment for hypertension?
a. ACE inhibitors
b. Beta blockers
c. Anticoagulants
d. Opioids
, a. ACE inhibitors
Rationale: ACE inhibitors are frequently prescribed as initial therapy for hypertension
due to their effectiveness and renal protection.
4. A patient taking warfarin is at risk for which complication?
a. Hyperkalemia
b. Bleeding
c. Hypertension
d. Constipation
b. Bleeding
Rationale: Warfarin is an anticoagulant that reduces clot formation, increasing the
risk for bleeding.
5. Which lab test monitors heparin therapy?
a. INR
b. PT
c. aPTT
d. CBC
c. aPTT
Rationale: Activated partial thromboplastin time (aPTT) monitors the effectiveness of
heparin anticoagulation.
6. The antidote for benzodiazepine overdose is:
a. Naloxone
b. Protamine sulfate
c. Flumazenil
d. Atropine
c. Flumazenil
Rationale: Flumazenil is a benzodiazepine receptor antagonist that reverses sedation
and respiratory depression.
7. Which drug is contraindicated in patients with asthma?
a. Albuterol
b. Metoprolol
c. Prednisone
d. Ipratropium
b. Metoprolol
Rationale: Beta-blockers can cause bronchospasm, worsening asthma.
8. What is the main adverse effect of aminoglycosides like gentamicin?
a. Ototoxicity
b. Constipation
c. Hypertension
, d. Hypoglycemia
a. Ototoxicity
Rationale: Aminoglycosides can damage the inner ear and cause hearing loss.
9. A nurse is preparing to administer furosemide. Which lab value requires monitoring?
a. Sodium
b. Potassium
c. Calcium
d. Platelets
b. Potassium
Rationale: Furosemide (a loop diuretic) causes potassium loss, leading to
hypokalemia.
10. What is the therapeutic range of lithium for bipolar disorder?
a. 0.2–0.5 mEq/L
b. 0.6–1.2 mEq/L
c. 2–4 mEq/L
d. 5–10 mEq/L
b. 0.6–1.2 mEq/L
Rationale: Lithium toxicity occurs above 1.5 mEq/L; therapeutic range is 0.6–1.2
mEq/L.
11. Which insulin has the fastest onset of action?
a. Regular insulin
b. NPH insulin
c. Lispro insulin
d. Glargine insulin
c. Lispro insulin
Rationale: Lispro is a rapid-acting insulin with onset within 15 minutes.
12. Which adverse effect is associated with ACE inhibitors?
a. Dry cough
b. Constipation
c. Hyperglycemia
d. Blurred vision
a. Dry cough
Rationale: ACE inhibitors cause buildup of bradykinin, leading to persistent cough.
13. Which drug is used to treat status epilepticus?
a. Phenytoin
b. Diazepam
c. Carbamazepine
With Actual 120 Questions & Verified
Answers,Plus Rationales/Expert
Verified For Guaranteed Pass Graded
A+/ 2025/2026 /Latest Update/Instant
Download Pdf
NR 341 Pharmacology Exam
1. Which medication is most commonly used to reverse opioid overdose?
a. Morphine
b. Naloxone
c. Flumazenil
d. Naltrexone
b. Naloxone
Rationale: Naloxone is an opioid antagonist that rapidly reverses respiratory
depression caused by opioid overdose.
2. A nurse is administering digoxin. What is the most important assessment before
giving the dose?
a. Respiratory rate
b. Apical pulse
c. Oxygen saturation
d. Blood glucose
b. Apical pulse
Rationale: Digoxin can cause bradycardia. The apical pulse should be checked for 1
full minute; hold if less than 60 bpm.
3. Which drug class is first-line treatment for hypertension?
a. ACE inhibitors
b. Beta blockers
c. Anticoagulants
d. Opioids
, a. ACE inhibitors
Rationale: ACE inhibitors are frequently prescribed as initial therapy for hypertension
due to their effectiveness and renal protection.
4. A patient taking warfarin is at risk for which complication?
a. Hyperkalemia
b. Bleeding
c. Hypertension
d. Constipation
b. Bleeding
Rationale: Warfarin is an anticoagulant that reduces clot formation, increasing the
risk for bleeding.
5. Which lab test monitors heparin therapy?
a. INR
b. PT
c. aPTT
d. CBC
c. aPTT
Rationale: Activated partial thromboplastin time (aPTT) monitors the effectiveness of
heparin anticoagulation.
6. The antidote for benzodiazepine overdose is:
a. Naloxone
b. Protamine sulfate
c. Flumazenil
d. Atropine
c. Flumazenil
Rationale: Flumazenil is a benzodiazepine receptor antagonist that reverses sedation
and respiratory depression.
7. Which drug is contraindicated in patients with asthma?
a. Albuterol
b. Metoprolol
c. Prednisone
d. Ipratropium
b. Metoprolol
Rationale: Beta-blockers can cause bronchospasm, worsening asthma.
8. What is the main adverse effect of aminoglycosides like gentamicin?
a. Ototoxicity
b. Constipation
c. Hypertension
, d. Hypoglycemia
a. Ototoxicity
Rationale: Aminoglycosides can damage the inner ear and cause hearing loss.
9. A nurse is preparing to administer furosemide. Which lab value requires monitoring?
a. Sodium
b. Potassium
c. Calcium
d. Platelets
b. Potassium
Rationale: Furosemide (a loop diuretic) causes potassium loss, leading to
hypokalemia.
10. What is the therapeutic range of lithium for bipolar disorder?
a. 0.2–0.5 mEq/L
b. 0.6–1.2 mEq/L
c. 2–4 mEq/L
d. 5–10 mEq/L
b. 0.6–1.2 mEq/L
Rationale: Lithium toxicity occurs above 1.5 mEq/L; therapeutic range is 0.6–1.2
mEq/L.
11. Which insulin has the fastest onset of action?
a. Regular insulin
b. NPH insulin
c. Lispro insulin
d. Glargine insulin
c. Lispro insulin
Rationale: Lispro is a rapid-acting insulin with onset within 15 minutes.
12. Which adverse effect is associated with ACE inhibitors?
a. Dry cough
b. Constipation
c. Hyperglycemia
d. Blurred vision
a. Dry cough
Rationale: ACE inhibitors cause buildup of bradykinin, leading to persistent cough.
13. Which drug is used to treat status epilepticus?
a. Phenytoin
b. Diazepam
c. Carbamazepine
