PAPER 2026 QUESTIONS AND SOLUTIONS
GRADED A+
◍ Aldosterone antagonists treat Answer:hypertension, and symptoms
for heart failure following a myocardial infarction.
◍ Ace inhibitors treat ? Answer:Hypertension
Heart failure
Disbetic nephropathy
Left ventricular dysfunction following MI
◍ Ace inhibitor
Prototype drug and other drugs Answer:Prototype: captopril (Capoten)
Other drugs: enalapril (Vasotec)
fosinopril (Monopril)
lisinopril ( Prinivil)
◍ Ace inhibitors blocks production of________
Which causes? Answer:Angiotensin ll
,Vasodilation
Urinary excretion of sodium and water
Urinary retention of potassium
◍ Ace inhibitors adverse effects: Answer:Captopril
C-cough
A-angioedema
P-potassium elevation(hyperkalemia)
T- taste changes
O-ortho hypotension(first dose)
P- pregnancy contra
R- renal stenosis
I-inflammationpain
L- low GFR
◍ Ace precautions Answer:Start ace inhibitors with low dose; gradually
increase
Diuretics may be temporarily stopped
Monitor bp
◍ How often should you take ace inhibitors? Answer:2-3 times daily
for hypertension
, 3 times daily gor heart failure
◍ When should captopril be given? Answer:1 hr before meals for
adequate absorption
◍ Ace inhibitors contraindications Answer:Pregnancy risk category D
Angioedema hypotension
Liver disease
◍ Ace inhibitors interaction with potassium sparring diuretics,
potassium supplements, or salt tablets Answer:Increase risk for
hyperkalemia
◍ Ace inhibitor interaction with antihypertensive, diuretics, and nitrates
Answer:Increase hypotension
◍ Ace inhibitor interaction with NSAIDS Answer:May decrease
effectiveness
◍ Ace inhibitors may cause_______ toxicity Answer:Lithium
◍ Treat severe hypotension with ARB drugs Answer:IV fluid therapy to
expand blood volume