Pharm 1141: Elimination, Fluid & Electrolytes, Perfusion
1. Where do loop diuretics work?: Loop of Henle
2. Diuretics indications: Heart failure
reducing edema
hypertension
3. Assessment for diuretics: - baseline fluid excess
- take weight
- assess for SOB
- contraindications: renal and hepatic disease, cross sensitivity, pregnancy, concurrent drug therapy
chest x-ray for pulmonary edema
4. With diuretics, always check...: hepatic function, renal, chemistry
5. Normal eGFR: > 60 mL/min
6. Normal Creatinine lab values: 0.6-1.2 mg/dL
7. increased BUN/creatinine ratio: dehydration
1/3
, 8. Decreased BUN/ creatinine ratio: liver disease and malnutrition
9. Signs of fluid problem: thready pulse
low weight
10. People susceptible to electrolyte imbalance: History of renal or cardiac disease
hormonal disorders
massive trauma or burns
11. When to take diuretics: morning
12. When to report weight gain: 2 pounds in 2 days
13. 1 kg=: 2.2 lbs
14. Carbonic Anhydrase Inhibitor: Decrease intraocular pressure
respiratory stimulant
15. Acetazolamide: Diamox- glaucoma
16. Sulfonamide-Type Loop Diuretics: Furosemide
2/3
1. Where do loop diuretics work?: Loop of Henle
2. Diuretics indications: Heart failure
reducing edema
hypertension
3. Assessment for diuretics: - baseline fluid excess
- take weight
- assess for SOB
- contraindications: renal and hepatic disease, cross sensitivity, pregnancy, concurrent drug therapy
chest x-ray for pulmonary edema
4. With diuretics, always check...: hepatic function, renal, chemistry
5. Normal eGFR: > 60 mL/min
6. Normal Creatinine lab values: 0.6-1.2 mg/dL
7. increased BUN/creatinine ratio: dehydration
1/3
, 8. Decreased BUN/ creatinine ratio: liver disease and malnutrition
9. Signs of fluid problem: thready pulse
low weight
10. People susceptible to electrolyte imbalance: History of renal or cardiac disease
hormonal disorders
massive trauma or burns
11. When to take diuretics: morning
12. When to report weight gain: 2 pounds in 2 days
13. 1 kg=: 2.2 lbs
14. Carbonic Anhydrase Inhibitor: Decrease intraocular pressure
respiratory stimulant
15. Acetazolamide: Diamox- glaucoma
16. Sulfonamide-Type Loop Diuretics: Furosemide
2/3
