DEEP VEIN THROMBOSIS EXAM
QUESTIONS AND ANSWERS
What can be used to to effectively diagnose the presence of acute or chronic venous
thrombosis in the veins. - answer- Duplex Sonography
is Duplex sonography a reliable method of determining the extent of chronic venous
disease? yes/no - answer- yes
What is the most common reason for the clinical evaluation of the extremity veins? -
answer- Suspected deep venous thrombosis (DVT)-
What is the estimation of annual incidence of DVT in the United States ? - answer-
over 2.5 million cases.
The % of untreated patients with DVT will sustain a nonfatal PE is? - answer- About
25%
PE is associated with a mortality rate of approximately 30%. with or without
treatment - answer- without treatment
when was the first susceptibility to develop venous thrombosis was described ? -
answer- in 1865
Virchow's triad consists of - answer- Venous stasis
Endothelial damage
Hypercoagulability
See picture in slide 4
Thrombogenesis - answer- the formation of a thrombus.
what does Inherited prothrombotic- do? - answer- describes any agent or condition
that leads to thrombosis) states have increased in frequency over the past 20 years.
This category of venous thrombosis is considered nonreversible - answer- Inherited
prothrombotic-
Clinical conditions that influence venous thrombosis - answer- 1,Inherited
prothrombotic-
2,Antithrombin III deficiency
3,Pregnancy and the postpartum period-
4,Oral contraceptives and hormone replacement therapy-
5,Antiphospholipid antibody syndrome-
6,Protein C and protein S are vitamin K-dependent-
7,Factor V Leiden-
, What category was the first reported congenital thrombotic condition - answer-
Antithrombin III deficiency
Isolated spontaneous thrombosis has been described with this condition - answer-
Precipitating circumstances:
Trauma
Pregnancy
Surgical procedures
Antithrombin III deficiency - answer- It is transmitted in an autosomal dominant (a
pattern of inheritance in which an affected individual has one copy of a mutant gene
and one normal gene on a pair of autosomal chromosomes
Pregnancy and the postpartum period- lower or higher - answer- higher risk for
developing DVT than the nonpregnant state.
what is a leading cause of maternal death after childbirth. - answer- PE (1 fatal PE
per 100,000 births)
what can increase the risk for DVT in premenopausal and postmenopausal women?
- answer- Oral contraceptives and hormone replacement therapy-
(The prevalence of DVT in women receiving oral contraceptives of 1 to 3 in 10,000)
Antiphospholipid antibody syndrome- refers to? - answer- it refers to the presence of
either the lupus anticoagulant antibody or anticardiolipin antibodies.
Protein C and protein S are vitamin K-dependent- - answer- Protein C or S
deficiency results in a sevenfold increased risk for developing venous thrombosis
( see picture slide 10)
What is Factor V Leiden- ? - answer- blood clotting disorder.
most common inherited hypercoagulable condition.
present in 12% to 33% of patients with spontaneous DVT .
protein that is needed for blood to clot properly.
The different gene that makes the Factor V Leiden protein is inherited from one or
both parents. True or False - answer- True
The Factor V Leiden protein is harder to "turn off" or Turn on than the normal Factor
V protein. This makes blood clots more likely to form, a condition called
thrombophilia. - answer- Turn off
Insufficient clotting power leads to bleeding problems.
Too much clotting power can lead to the formation of blood clots. True or False -
answer- True
A blood test (called a screening test) - answer- can reveal Activated Protein C
resistance. Another blood test that examines the genes (called DNA) will be done to
find out if Factor V Leiden is the cause of the resistance and what type of Factor V
Leiden a person has.
QUESTIONS AND ANSWERS
What can be used to to effectively diagnose the presence of acute or chronic venous
thrombosis in the veins. - answer- Duplex Sonography
is Duplex sonography a reliable method of determining the extent of chronic venous
disease? yes/no - answer- yes
What is the most common reason for the clinical evaluation of the extremity veins? -
answer- Suspected deep venous thrombosis (DVT)-
What is the estimation of annual incidence of DVT in the United States ? - answer-
over 2.5 million cases.
The % of untreated patients with DVT will sustain a nonfatal PE is? - answer- About
25%
PE is associated with a mortality rate of approximately 30%. with or without
treatment - answer- without treatment
when was the first susceptibility to develop venous thrombosis was described ? -
answer- in 1865
Virchow's triad consists of - answer- Venous stasis
Endothelial damage
Hypercoagulability
See picture in slide 4
Thrombogenesis - answer- the formation of a thrombus.
what does Inherited prothrombotic- do? - answer- describes any agent or condition
that leads to thrombosis) states have increased in frequency over the past 20 years.
This category of venous thrombosis is considered nonreversible - answer- Inherited
prothrombotic-
Clinical conditions that influence venous thrombosis - answer- 1,Inherited
prothrombotic-
2,Antithrombin III deficiency
3,Pregnancy and the postpartum period-
4,Oral contraceptives and hormone replacement therapy-
5,Antiphospholipid antibody syndrome-
6,Protein C and protein S are vitamin K-dependent-
7,Factor V Leiden-
, What category was the first reported congenital thrombotic condition - answer-
Antithrombin III deficiency
Isolated spontaneous thrombosis has been described with this condition - answer-
Precipitating circumstances:
Trauma
Pregnancy
Surgical procedures
Antithrombin III deficiency - answer- It is transmitted in an autosomal dominant (a
pattern of inheritance in which an affected individual has one copy of a mutant gene
and one normal gene on a pair of autosomal chromosomes
Pregnancy and the postpartum period- lower or higher - answer- higher risk for
developing DVT than the nonpregnant state.
what is a leading cause of maternal death after childbirth. - answer- PE (1 fatal PE
per 100,000 births)
what can increase the risk for DVT in premenopausal and postmenopausal women?
- answer- Oral contraceptives and hormone replacement therapy-
(The prevalence of DVT in women receiving oral contraceptives of 1 to 3 in 10,000)
Antiphospholipid antibody syndrome- refers to? - answer- it refers to the presence of
either the lupus anticoagulant antibody or anticardiolipin antibodies.
Protein C and protein S are vitamin K-dependent- - answer- Protein C or S
deficiency results in a sevenfold increased risk for developing venous thrombosis
( see picture slide 10)
What is Factor V Leiden- ? - answer- blood clotting disorder.
most common inherited hypercoagulable condition.
present in 12% to 33% of patients with spontaneous DVT .
protein that is needed for blood to clot properly.
The different gene that makes the Factor V Leiden protein is inherited from one or
both parents. True or False - answer- True
The Factor V Leiden protein is harder to "turn off" or Turn on than the normal Factor
V protein. This makes blood clots more likely to form, a condition called
thrombophilia. - answer- Turn off
Insufficient clotting power leads to bleeding problems.
Too much clotting power can lead to the formation of blood clots. True or False -
answer- True
A blood test (called a screening test) - answer- can reveal Activated Protein C
resistance. Another blood test that examines the genes (called DNA) will be done to
find out if Factor V Leiden is the cause of the resistance and what type of Factor V
Leiden a person has.
