NUR 315
Study online at https://quizlet.com/_hmbvak
1. Pharmacodynamics: Which term refers to the study of what drugs do to the body
2. X: category that represents the greatest risk for fetal harm according to the U.S. Food and Drug Administration
Pregnancy Risk Categories
3. American Nurses Association (ANA): nursing organization that published guidelines regarding
genetic and genomic competencies for nurses with advanced degrees
4. Which schedule classification has been assigned to heroin: schedule II
5. When teaching a pregnant patient about the effects of medication on the
fetus, the nurse recognizes the greatest harm from maternally ingested med-
ications affecting fetal development occurs during which time period: first trimester
6. When teaching a pregnant patient about the effects of medication on the
fetus, the nurse recognizes the greatest harm from maternally ingested med-
ications affecting fetal development occurs during which time period: Second and
third trimesters
7. Amphotericin-B: - Polyene antibiotic
- Treatment of systemic mycoses
- Highly toxic
- AE: Infusion reactions, nephrotoxicity, hypokalemia, hematologic affects
8. Azoles: Inhibit drug metabolizing enzymes
Less toxic than Amphotericin B
Oral or topical administration Systemic or superficial mycoses
Fluconazole, itraconazole
9. Nystatin: Common topical antifungal
Used in skin folds most commonly Can be used orally Usually, candidiasis treatment
10. Immunosuppressants: Suppresses immune system
Increase risk for infection
Bone marrow suppression
Many uses Organ transplant SLE RA
11. Tacrolimus: - topical
- Often used in conjunction with mycophenolate mofetil or glucocorticoids
12. Methotrexate: - Cytotoxic drug
- AE: N/V/D, HA, fatigue, cough.
- Major toxicities: hepatic fibrosis, bone marrow suppression, GI ulceration, pneumonitis
1/7
, NUR 315
Study online at https://quizlet.com/_hmbvak
- Contraindicated in patients with: blood dyscrasias, immunodeficiency, liver disease
-Screen for TB prior to initial administration
13. NRTI's: Lactic acidosis, hepatomegaly, nephrotoxicity, bone density loss
14. NNRTI's: CNS effects
15. Protease Inhibitors: Hyperlipidemia, insulin resistance, diarrhea
16. Integrase Inhibitors: Stevens Johnson Syndrome
17. Allergic reactions to abacavier: hypersensitivity linked to HLA-B*57:01 gene (people with this gene
are hypersensitive to antiretroviral medications)
18. What is the biggest electrolyte imbalance to monitor for when giving Am-
photericin B?: hypokalemia
19. What major liver-related lab should be monitored when a patient is on azole
antifungals?: ALT's
20. What is a common side effect of azole antifungals like fluconazole?: N/V/D/AB
pain
21. What is the best patient teaching for oral Nystatin administration for oral
thrush?: Swish the medication in the mouth thoroughly for several minutes, Hold it in the mouth as long as possible,
Use after meals and do not eat or drink for 30 minutes after use, Continue full course even if symptoms improve, Shake
the suspension well before each dose, Rinse the mouth before use if there's food or debri
22. What is the priority lab to monitor for a patient on Tacrolimus?: trough blood leve
23. What infection risk education should be emphasized for patients on My-
cophenolate Mofetil?: Avoid crowds and sick people to reduce exposure to viruses and bacteria
Wash hands often with soap and water
Report any signs of infection such as fever, chills, sore throat, or cough
Do not get live vaccines without provider approval
Practice safe food handling to avoid foodborne illness
Use protection during sex if at risk for STIs
24. What is an important reproductive warning for women taking Methotrexate
for RA?: teratogenic
25. What nursing assessment is critical when a patient is on Pyridostigmine?: -
swallowing and respiratory status
26. What is the hallmark difference between cholinergic crisis and myasthenic
crisis?: Cholinergic crisis worsens with more acetylcholine; myasthenic crisis improves
2/7
Study online at https://quizlet.com/_hmbvak
1. Pharmacodynamics: Which term refers to the study of what drugs do to the body
2. X: category that represents the greatest risk for fetal harm according to the U.S. Food and Drug Administration
Pregnancy Risk Categories
3. American Nurses Association (ANA): nursing organization that published guidelines regarding
genetic and genomic competencies for nurses with advanced degrees
4. Which schedule classification has been assigned to heroin: schedule II
5. When teaching a pregnant patient about the effects of medication on the
fetus, the nurse recognizes the greatest harm from maternally ingested med-
ications affecting fetal development occurs during which time period: first trimester
6. When teaching a pregnant patient about the effects of medication on the
fetus, the nurse recognizes the greatest harm from maternally ingested med-
ications affecting fetal development occurs during which time period: Second and
third trimesters
7. Amphotericin-B: - Polyene antibiotic
- Treatment of systemic mycoses
- Highly toxic
- AE: Infusion reactions, nephrotoxicity, hypokalemia, hematologic affects
8. Azoles: Inhibit drug metabolizing enzymes
Less toxic than Amphotericin B
Oral or topical administration Systemic or superficial mycoses
Fluconazole, itraconazole
9. Nystatin: Common topical antifungal
Used in skin folds most commonly Can be used orally Usually, candidiasis treatment
10. Immunosuppressants: Suppresses immune system
Increase risk for infection
Bone marrow suppression
Many uses Organ transplant SLE RA
11. Tacrolimus: - topical
- Often used in conjunction with mycophenolate mofetil or glucocorticoids
12. Methotrexate: - Cytotoxic drug
- AE: N/V/D, HA, fatigue, cough.
- Major toxicities: hepatic fibrosis, bone marrow suppression, GI ulceration, pneumonitis
1/7
, NUR 315
Study online at https://quizlet.com/_hmbvak
- Contraindicated in patients with: blood dyscrasias, immunodeficiency, liver disease
-Screen for TB prior to initial administration
13. NRTI's: Lactic acidosis, hepatomegaly, nephrotoxicity, bone density loss
14. NNRTI's: CNS effects
15. Protease Inhibitors: Hyperlipidemia, insulin resistance, diarrhea
16. Integrase Inhibitors: Stevens Johnson Syndrome
17. Allergic reactions to abacavier: hypersensitivity linked to HLA-B*57:01 gene (people with this gene
are hypersensitive to antiretroviral medications)
18. What is the biggest electrolyte imbalance to monitor for when giving Am-
photericin B?: hypokalemia
19. What major liver-related lab should be monitored when a patient is on azole
antifungals?: ALT's
20. What is a common side effect of azole antifungals like fluconazole?: N/V/D/AB
pain
21. What is the best patient teaching for oral Nystatin administration for oral
thrush?: Swish the medication in the mouth thoroughly for several minutes, Hold it in the mouth as long as possible,
Use after meals and do not eat or drink for 30 minutes after use, Continue full course even if symptoms improve, Shake
the suspension well before each dose, Rinse the mouth before use if there's food or debri
22. What is the priority lab to monitor for a patient on Tacrolimus?: trough blood leve
23. What infection risk education should be emphasized for patients on My-
cophenolate Mofetil?: Avoid crowds and sick people to reduce exposure to viruses and bacteria
Wash hands often with soap and water
Report any signs of infection such as fever, chills, sore throat, or cough
Do not get live vaccines without provider approval
Practice safe food handling to avoid foodborne illness
Use protection during sex if at risk for STIs
24. What is an important reproductive warning for women taking Methotrexate
for RA?: teratogenic
25. What nursing assessment is critical when a patient is on Pyridostigmine?: -
swallowing and respiratory status
26. What is the hallmark difference between cholinergic crisis and myasthenic
crisis?: Cholinergic crisis worsens with more acetylcholine; myasthenic crisis improves
2/7
