NSC 830 ADVANCED PHARMACOLOGY-ACTUAL EXAM-LATEST UPDATE 2025 |
COMPLETE QUESTIONS WITH CORRECT DETAILED AND VERIFIED ANSWERS |
RATED 100% CORRECT!! ALREADY GRADED A+ | GUARANTEED PASS!!
Narrow Specturm - (answers)Treat limited # of organisms, Less likely to disrupt normal flora,
organism identified.
Broad Specturm - (answers)Treats multiple organisms, more likely to disrupt normal flora,
causative agent unknown.
Why would you select abx? - (answers)Is antimicrobial therapy indicated, make a clinical
diagnosis, collection of specimens for a cx or lab test, make microbial diagnosis, select drug.
Extended spectrum - (answers)treats multiple organisms, more likely to disrupt normal flora,
used when causative organism is unknown.
Gram positive - (answers)Purple, thick layer
Example of gram positive - (answers)Group A beta-strep
Strep PNA
Gram negative - (answers)Red or pink, thin layer
Example of gram negative - (answers)H. influenza
N. Gonoccocus
Atypical Organism - (answers)colorless, no layer
Example of Atypical organism - (answers)Macrolides- erythromycins
True or False: Atypical bacteria are resistent to becta-lactum abx - (answers)True
,Risk factors for Drug Resistant Strep PNA (DRSP) - (answers)Recent abx use
Older >65
Multiple Comorbidtities ( COPD, DM, HF, renal failure)
Daycare worker
Alcoholism
Immunosuppressed (including chronic steroid use >10 mg/day long term).
Treatment for Drug Resistant Strep PNA - (answers)High dose amoxicillin 3-4g/day
Respiratory fluoroquinolones: moxifloxican, gemifloxican, levofloxacin.
Tehlithromycin: use limited due to hepatoxicity
Factors to determine when selecting an abx... - (answers)Allergy history (PCN- risk of cross
allergy with cephalosporins)
Age- (Renal function- neonates and elderly)
Pregnancy
Immunocompromised status
Affordability
Taste and convenience
What are 2 abx contraindicated in pregnancy? - (answers)tetracyclines
fluoroquinolone
Do immunocompromised patients get bactericidal or baceriostiatic? - (answers)Bactericidals
What are bactericidals? - (answers)Kills bacteria
What are bacteriostatic? - (answers)Restrains production of bacteria. The patient needs a good
immune system.
, Minimum inhibitory concentration (MIC) - (answers)Min. amount of abx used to inhibit growth
of bacteria. Abx usually dosed 2-4 times MIC
Teaching the patient to ..... - (answers)Take ALL of medication
May need back up birth control and for 7 days after.
Report signs of allergic reaction (SOA, Wheezing, rash)
General side effects of abx - (answers)Hypersensitivity: (allergic reaction-rash, itching, LBP,
wheezing, SOA).
Diarrhea: make sure to report blood, mucous
Superinfection: Due to disruption of normal flora (oral thrush, yeast infection)
True or False: Is extended care more likely to cause diarrhea? - (answers)True
Examples of Beta-Lactam Abx? - (answers)PCN & Cephalosporins
What do Beta-Lactam abx have on them? - (answers)A ring- that works by disrupting the
biosynthesis of the cell wall.
Intact ring is essential for antibacterial activity? True or False - (answers)True
True or false- A beta-lactamase inhibitor can be combine with an abx to form a beta-lactamase
resistant compound? - (answers)True
What are some examples of beta-lactamate inhibitors? - (answers)Clavulanic acid
tazobactam
sulbactam
COMPLETE QUESTIONS WITH CORRECT DETAILED AND VERIFIED ANSWERS |
RATED 100% CORRECT!! ALREADY GRADED A+ | GUARANTEED PASS!!
Narrow Specturm - (answers)Treat limited # of organisms, Less likely to disrupt normal flora,
organism identified.
Broad Specturm - (answers)Treats multiple organisms, more likely to disrupt normal flora,
causative agent unknown.
Why would you select abx? - (answers)Is antimicrobial therapy indicated, make a clinical
diagnosis, collection of specimens for a cx or lab test, make microbial diagnosis, select drug.
Extended spectrum - (answers)treats multiple organisms, more likely to disrupt normal flora,
used when causative organism is unknown.
Gram positive - (answers)Purple, thick layer
Example of gram positive - (answers)Group A beta-strep
Strep PNA
Gram negative - (answers)Red or pink, thin layer
Example of gram negative - (answers)H. influenza
N. Gonoccocus
Atypical Organism - (answers)colorless, no layer
Example of Atypical organism - (answers)Macrolides- erythromycins
True or False: Atypical bacteria are resistent to becta-lactum abx - (answers)True
,Risk factors for Drug Resistant Strep PNA (DRSP) - (answers)Recent abx use
Older >65
Multiple Comorbidtities ( COPD, DM, HF, renal failure)
Daycare worker
Alcoholism
Immunosuppressed (including chronic steroid use >10 mg/day long term).
Treatment for Drug Resistant Strep PNA - (answers)High dose amoxicillin 3-4g/day
Respiratory fluoroquinolones: moxifloxican, gemifloxican, levofloxacin.
Tehlithromycin: use limited due to hepatoxicity
Factors to determine when selecting an abx... - (answers)Allergy history (PCN- risk of cross
allergy with cephalosporins)
Age- (Renal function- neonates and elderly)
Pregnancy
Immunocompromised status
Affordability
Taste and convenience
What are 2 abx contraindicated in pregnancy? - (answers)tetracyclines
fluoroquinolone
Do immunocompromised patients get bactericidal or baceriostiatic? - (answers)Bactericidals
What are bactericidals? - (answers)Kills bacteria
What are bacteriostatic? - (answers)Restrains production of bacteria. The patient needs a good
immune system.
, Minimum inhibitory concentration (MIC) - (answers)Min. amount of abx used to inhibit growth
of bacteria. Abx usually dosed 2-4 times MIC
Teaching the patient to ..... - (answers)Take ALL of medication
May need back up birth control and for 7 days after.
Report signs of allergic reaction (SOA, Wheezing, rash)
General side effects of abx - (answers)Hypersensitivity: (allergic reaction-rash, itching, LBP,
wheezing, SOA).
Diarrhea: make sure to report blood, mucous
Superinfection: Due to disruption of normal flora (oral thrush, yeast infection)
True or False: Is extended care more likely to cause diarrhea? - (answers)True
Examples of Beta-Lactam Abx? - (answers)PCN & Cephalosporins
What do Beta-Lactam abx have on them? - (answers)A ring- that works by disrupting the
biosynthesis of the cell wall.
Intact ring is essential for antibacterial activity? True or False - (answers)True
True or false- A beta-lactamase inhibitor can be combine with an abx to form a beta-lactamase
resistant compound? - (answers)True
What are some examples of beta-lactamate inhibitors? - (answers)Clavulanic acid
tazobactam
sulbactam
