CU Boulder MCDB 3145 - 3 Review EXAM ACTUAL EXAM/
MOSTLY TESTED QUESTIONS AND CORRECT DETAILED
ANSWERS| 100% CORRECT SOLUTIONS/GRADE A+
What three substances make up the microtubles, microfilaments (aka actin
cytoskeleton? filaments), and intermediate filaments
By what forces is each of the three types
of filaments in the cytoskeleton held Weak, non-covalent forces
together?
What kind of subunits are microtubules
tubulin
made of?
What protein makes up microfilaments? actin
What is a general physical description of
tough, rope-like fibers
intermediate filaments?
,In what size range are nanomachines
10-100 nm
typically made?
What is a general physical description of
Hollow, relatively rigid, tubular structures
microtubules?
In what type of cells are microtubules
In nearly every variety of eukaryotic cell
found?
What type of filament is the mitotic
microtubules
spindle made of?
What is the diameter and the wall
diameter is 25 nm; wall thickness is 4 nm
thickness of a microtubule?
Along which axis of the microtubule are
The long axis
protofilaments aligned?
Globular proteins arranged in longitudinal
What are protofilaments?
rows that make up the walls of a microtubule
How many protofilaments make up the
13
cross-section of a microtubule?
, Dimeric building blocks of one alpha-tubulin
What are protofilaments made of?
and one beta-tubulin subunit
Which end of the microtubule is the
alpha is minus
alpha-tubulin aligned with? The beta-
beta is plus
subunit?
What is a MAP? microtubule-associated protein
They generally increase the stability of
What is the general function of MAPs?
microtubules and promote their assembly
By what is the microtubule-binding By the addition and removal of phosphate
activity of MAPs primarily controlled by? groups from particular amino acid residues
Excessive phosphorylation of which MAP
has been associated with the
tau
development of neurodegenerative
disorders?
What type of proteins use microtubules
motor proteins
as tracks?
Forces required to move objects through the
What do motor proteins generate?
cell
MOSTLY TESTED QUESTIONS AND CORRECT DETAILED
ANSWERS| 100% CORRECT SOLUTIONS/GRADE A+
What three substances make up the microtubles, microfilaments (aka actin
cytoskeleton? filaments), and intermediate filaments
By what forces is each of the three types
of filaments in the cytoskeleton held Weak, non-covalent forces
together?
What kind of subunits are microtubules
tubulin
made of?
What protein makes up microfilaments? actin
What is a general physical description of
tough, rope-like fibers
intermediate filaments?
,In what size range are nanomachines
10-100 nm
typically made?
What is a general physical description of
Hollow, relatively rigid, tubular structures
microtubules?
In what type of cells are microtubules
In nearly every variety of eukaryotic cell
found?
What type of filament is the mitotic
microtubules
spindle made of?
What is the diameter and the wall
diameter is 25 nm; wall thickness is 4 nm
thickness of a microtubule?
Along which axis of the microtubule are
The long axis
protofilaments aligned?
Globular proteins arranged in longitudinal
What are protofilaments?
rows that make up the walls of a microtubule
How many protofilaments make up the
13
cross-section of a microtubule?
, Dimeric building blocks of one alpha-tubulin
What are protofilaments made of?
and one beta-tubulin subunit
Which end of the microtubule is the
alpha is minus
alpha-tubulin aligned with? The beta-
beta is plus
subunit?
What is a MAP? microtubule-associated protein
They generally increase the stability of
What is the general function of MAPs?
microtubules and promote their assembly
By what is the microtubule-binding By the addition and removal of phosphate
activity of MAPs primarily controlled by? groups from particular amino acid residues
Excessive phosphorylation of which MAP
has been associated with the
tau
development of neurodegenerative
disorders?
What type of proteins use microtubules
motor proteins
as tracks?
Forces required to move objects through the
What do motor proteins generate?
cell
