NUR 370 (Hematological - Exam 3 with
complete solutions latest version
Sickle Cell Patho - CORRECT ANSWER-Oxygen de-saturation (cell changes to
sickled shape)
Causes vaso-occlusion & micro-circulation, from obstruction
Hemolysis (premature destruction of RBC's) (compensation with increased
production)
Deoxygenate (get sticky and caught on each other)
Sickle Cell CM's - CORRECT ANSWER-- Anemia shows after 6mo
- Obstruction of microcirculation, ischemia
- Leg ulcers, Recurrent infections, Priapism, Hematuria, Bone weakness,
Enuresis
- Increased susceptibility to pneumococcal and salmonella
- Poor feeding, poor weight gain, irritability, fatigue
- Chronic vaso-occlusion affecting any system
*varies in severity and frequency*
Sickle Cell Types of Crises - CORRECT ANSWER-- Vaso-occlusive episode (VOE)
- Splenic sequestration
- Aplastic crisis
SCD; Vaso-Occlusive Episode (VOE) Crisis - CORRECT ANSWER-- Painful
episode
- Hypoxic damage, ischemia, necrosis, pain
- Can affect any body tissue or organ
- CM's depend on what tissue or organ is involved
SCD; Splenic Sequestration Crisis - CORRECT ANSWER-Pooling of blood in the
spleen and liver - hypotension & shock
SCD; Aplastic Crisis - CORRECT ANSWER-Diminished or absent production of all
blood cells
BRAINSCAPE1
, BRAINSCAPE1
Sickle Cell Disease Parent Teaching - CORRECT ANSWER-- S/S of crisis,
importance of early intervention
- Prompt medical attention for fevers and other signs of illness
- Maintaining hydration
- Recognize enuresis as a manifestation of the illness
- Avoid under-medicating - pain prevention is needed
- Around the clock pain meds
- Psychological Support
- Heat packs NOT ICE
- Knowing that the pain they are feeling is real
- Recognition of complications, especially chest syndrome or CVA
Sickle Cell Disease Hospital Care During Crisis - CORRECT ANSWER--
Supplemental O2
- Transfusions
- Splenectomy
- Chelation therapy w/Desferal (may need to be reduced hemosiderosis due to
iron overload)
- Stem cell transplant
- Prevent the conditions that promote sickling
- Treat medical emergencies of sickle cell crisis
SCD; Hospital Care During Crisis - How to prevent the conditions that promote
sickling - CORRECT ANSWER-Maintain hydration and prevent
desaturation/hypoxemia
SCD; Hospital Care During Crisis - How to treat medical emergencies of sickle
cell crisis - CORRECT ANSWER-- Bed rest to minimize O2 use
- Hydration
- Prevent/correct electrolyte imbalance or metabolic acidosis
Patho for Iron Deficiency Anemia - CORRECT ANSWER-Inadequate intake, excess
demand, malabsorption, or impaired hemoglobin synthesis; overweight or
underweight
CM's for Iron Deficiency Anemia - CORRECT ANSWER-- Hypovolemic
- Being pale or having yellow "sallow" skin
- Unexplained fatigue or lack of energy
- SOB
- Chest pain
- Unexplained generalized weakness
- Rapid HR
- Pounding or "whooshing" in ears
- Craving for ice or clay "-pichophagia"
- Sore or smooth tongue, swollen
- Brittle nails or hair loss
- Enlarged spleen
BRAINSCAPE1