NSC 830 Advanced Pharmacology exam questions with answers

NSC 830 Advanced Pharmacology exam
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questions with answers |\ |\




Narrow Specturm - CORRECT ANSWERS ✔✔Treat limited # of
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organisms, Less likely to disrupt normal flora, organism identified.
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Broad Specturm - CORRECT ANSWERS ✔✔Treats multiple
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organisms, more likely to disrupt normal flora, causative agent
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unknown.


Why would you select abx? - CORRECT ANSWERS ✔✔Is
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antimicrobial therapy indicated, make a clinical diagnosis,
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collection of specimens for a cx or lab test, make microbial
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diagnosis, select drug. |\ |\




Extended spectrum - CORRECT ANSWERS ✔✔treats multiple
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organisms, more likely to disrupt normal flora, used when
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causative organism is unknown. |\ |\ |\




Gram positive - CORRECT ANSWERS ✔✔Purple, thick layer
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Example of gram positive - CORRECT ANSWERS ✔✔Group A beta-
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strep
Strep PNA|\




Gram negative - CORRECT ANSWERS ✔✔Red or pink, thin layer
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,Example of gram negative - CORRECT ANSWERS ✔✔H. influenza
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N. Gonoccocus
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Atypical Organism - CORRECT ANSWERS ✔✔colorless, no layer
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Example of Atypical organism - CORRECT ANSWERS
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✔✔Macrolides- erythromycins |\




True or False: Atypical bacteria are resistent to becta-lactum abx -
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CORRECT ANSWERS ✔✔True
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Risk factors for Drug Resistant Strep PNA (DRSP) - CORRECT
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ANSWERS ✔✔Recent abx use |\ |\ |\




Older >65 |\




Multiple Comorbidtities ( COPD, DM, HF, renal failure)
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Daycare worker |\




Alcoholism
Immunosuppressed (including chronic steroid use >10 mg/day |\ |\ |\ |\ |\ |\ |\


long term).
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Treatment for Drug Resistant Strep PNA - CORRECT ANSWERS
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✔✔High dose amoxicillin 3-4g/day
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Respiratory fluoroquinolones: moxifloxican, gemifloxican,
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levofloxacin. |\




Tehlithromycin: use limited due to hepatoxicity |\ |\ |\ |\ |\

, Factors to determine when selecting an abx... - CORRECT
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ANSWERS ✔✔Allergy history (PCN- risk of cross allergy with
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cephalosporins)
Age- (Renal function- neonates and elderly)
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Pregnancy
Immunocompromised status |\




Affordability
Taste and convenience
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What are 2 abx contraindicated in pregnancy? - CORRECT
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ANSWERS ✔✔tetracyclines |\




fluoroquinolone


Do immunocompromised patients get bactericidal or
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baceriostiatic? - CORRECT ANSWERS ✔✔Bactericidals |\ |\ |\ |\




What are bactericidals? - CORRECT ANSWERS ✔✔Kills bacteria
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What are bacteriostatic? - CORRECT ANSWERS ✔✔Restrains
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production of bacteria. The patient needs a good immune
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system.


Minimum inhibitory concentration (MIC) - CORRECT ANSWERS
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✔✔Min. amount of abx used to inhibit growth of bacteria. Abx
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usually dosed 2-4 times MIC
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