ANTH 246 - Week 4 Activity - University of Illinois, Urbana Champaign ANTH 246

Week 4 Activity: Attempt review 2/20/21, 16:12




Dashboard / My courses / ANTH 246 ONL SP21 / Week 4 / Week 4 Activity




Started on Saturday, February 20, 2021, 4:04 PM
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Completed on Saturday, February 20, 2021, 4:09 PM
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Time taken 4 mins 58 secs

Information
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Did you complete the Practice for Week 4 Activity first? The practice is not graded and can ensure you understand how to do the
calculations!
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For this Activity you get 2 attempts. It is extremely important that you do not hit
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the back arrow icon on your browser to try to re answer a question/look at old
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answers, as it will count this as your second attempt!!! G
As you go through the questions, keep a record of your answers in a separate document for reference, so that when you start
your second attempt at the Activity, you can know what you answered before!



Part 1: Calculating Genotype Frequencies and RMP
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Do the calculations and answer the questions on the following slides.
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You may find it helpful to record your answers to each question as they may be useful for answering later questions.
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,Week 4 Activity: Attempt review 2/20/21, 16:12



Question 1

Correct

Points out of 1.00




Here is an example using 3 CODIS STR results. DNA evidence was found at a crime scene. Due to the poor quality of the DNA
sample, only 3 of the 13 CODIS STRs could be determined. The table below lists the analytical results for the three STRs in the
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second and third columns (Allele A and Allele B).

STR Locus Allele A Allele B P(Allele A) P(Allele B)
D3S1358 11 12 0.5 0.2
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TH01 4 4 0.5 0.5
D21S11 7 10 C 0.1 0.5


Which STR is homozygous for the DNA evidence? Recall that homozygosity means that for a given locus, an individual has 2
identical alleles.

Select one:
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a. TH01 !
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b. D3S1358

c. D21S11
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Question 2
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Correct

Points out of 1.00
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STR LocusAllele AAllele BP(Allele A)P(Allele B)
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D3S1358 11 12 0.5 0.2
TH01 4 4 0.5 0.5
D21S11 7 10 0.1 0.5
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In this table, the probabilities for the DNA evidence's alleles have already been established based on population frequencies in
the CODIS database and are presented in the 2 far right columns.
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Based on the probabilities (i.e. frequencies) for the various alleles for all 3 STRs, which allele is the rarest in the source
population? N
Select one:
a. Allele 7 in D21S11 !

b. Allele 4 at TH01

c. Allele 10 at D21S11

d. Allele 11 at D3S1358

e. Allele 12 at D3S1358




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, Week 4 Activity: Attempt review 2/20/21, 16:12



Question 3

Correct

Points out of 1.00




STR LocusAllele AAllele BP(Allele A)P(Allele B)
D3S1358
S 11 12 0.5 0.2
TH01 4 4 0.5 0.5
D21S11 7 10 0.1 0.5
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And the most common allele(s)?

Select one:
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a. Allele 11 at D3S1358, Allele 4 at TH01, and Allele 10 at D21S11 !

b. Allele 4 at TH01
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c. Allele 11 at D3S1358
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d. Allele 7 at D21S11

e. Allele 12 at D3S1358
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Question 4
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Correct

Points out of 1.00
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STR LocusAllele AAllele BP(Allele A)P(Allele B)
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D3S1358 11 12 0.5 0.2
TH01 4 4 0.5 0.5
D21S11 7 10 0.1 0.5
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To calculate the RMP, we must first calculate the combined probabilities, or the genotype frequency, at each locus. Recall that the
calculations for heterozygous (2pq) and homozygous (p2) genotypes differ.
What is the genotype frequency for D3S1358? Write your answer as a decimal.


Answer: 0.2 !
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