TEST BANK FOR INTRODUCTORY CLINICAL PHARMACOLOGY
% COMPLETE GUIDE WITH A+ GRADE ASSURED!!!!
Protein Binding - CORRECT ANSWERS-Drugs can form reversible bonds with proteins
warfarin-aspirin interaction - CORRECT ANSWERS-binds to proteins and only 10% is absorbed
aspirin binds to protein ^ warfarin dose
Metabolism - CORRECT ANSWERS-Enzymatic alteration of drug structure
Plasma albumin - CORRECT ANSWERS-most abundant and important
large molecule
should remain in bloodstream
impacts drug distribution
impacts drug interactions
Where does drug metabolism take place? - CORRECT ANSWERS-mainly in the liver
what does the liver do to drugs - CORRECT ANSWERS-makes drugs water soluble for excretion
most important therapeutic function of metabolism
Hepatic Drug Metabolizing Enzymes - CORRECT ANSWERS-Most hepatic drug metabolism is
performed by the hepatic microsomal enzyme system(cytochrome P450)
FDA - CORRECT ANSWERS-US regulatory agencyApproval process
USP - CORRECT ANSWERS-Standardizes trial specimens
Ensures identity, strength, quality and purity of drugs
, Randomized Controlled Trial - CORRECT ANSWERS-Most reliable way to objectively assess
drug therapy
Randomized Controlled Trial characteristics - CORRECT ANSWERS-1. Control
2. Randomization
3. Blinding
• single: subjects only
• double: researchers and subjects both
Drug Names - CORRECT ANSWERS-1. Chemical name N-acetyl-para-aminophenol
2. Generic (USANC) acetaminophen
3. Trade/brand Tylenol, FeverAll, Infantaire.
Over-the-Counter Drugs - CORRECT ANSWERS-• >$20 billion spent annually on OTC drugs
• 60% of all drug doses administered
• 40% of US take at least one OTC drug every 2 days
Pharmacokinetics - CORRECT ANSWERS-what the body does to drugs
Pharmacodynamics - CORRECT ANSWERS-what drugs do to the body and how they do it
Pharmacokinetics Influenced by: - CORRECT ANSWERS-age
bio sex
body composition
drug interaction
Absorption - CORRECT ANSWERS-Rate determines how soon effects will begin
Amount helps determine intensity of the effects
% COMPLETE GUIDE WITH A+ GRADE ASSURED!!!!
Protein Binding - CORRECT ANSWERS-Drugs can form reversible bonds with proteins
warfarin-aspirin interaction - CORRECT ANSWERS-binds to proteins and only 10% is absorbed
aspirin binds to protein ^ warfarin dose
Metabolism - CORRECT ANSWERS-Enzymatic alteration of drug structure
Plasma albumin - CORRECT ANSWERS-most abundant and important
large molecule
should remain in bloodstream
impacts drug distribution
impacts drug interactions
Where does drug metabolism take place? - CORRECT ANSWERS-mainly in the liver
what does the liver do to drugs - CORRECT ANSWERS-makes drugs water soluble for excretion
most important therapeutic function of metabolism
Hepatic Drug Metabolizing Enzymes - CORRECT ANSWERS-Most hepatic drug metabolism is
performed by the hepatic microsomal enzyme system(cytochrome P450)
FDA - CORRECT ANSWERS-US regulatory agencyApproval process
USP - CORRECT ANSWERS-Standardizes trial specimens
Ensures identity, strength, quality and purity of drugs
, Randomized Controlled Trial - CORRECT ANSWERS-Most reliable way to objectively assess
drug therapy
Randomized Controlled Trial characteristics - CORRECT ANSWERS-1. Control
2. Randomization
3. Blinding
• single: subjects only
• double: researchers and subjects both
Drug Names - CORRECT ANSWERS-1. Chemical name N-acetyl-para-aminophenol
2. Generic (USANC) acetaminophen
3. Trade/brand Tylenol, FeverAll, Infantaire.
Over-the-Counter Drugs - CORRECT ANSWERS-• >$20 billion spent annually on OTC drugs
• 60% of all drug doses administered
• 40% of US take at least one OTC drug every 2 days
Pharmacokinetics - CORRECT ANSWERS-what the body does to drugs
Pharmacodynamics - CORRECT ANSWERS-what drugs do to the body and how they do it
Pharmacokinetics Influenced by: - CORRECT ANSWERS-age
bio sex
body composition
drug interaction
Absorption - CORRECT ANSWERS-Rate determines how soon effects will begin
Amount helps determine intensity of the effects
