Psychopharmacology Final Exam ACTUAL
QUESTIONS AND CORRECT ANSWERS
The process of releasing neurotransmitter molecules from the vesicles is known as _____ and
occurs as a result of an influx of _____ - Correct answers✔✔Exocytosis; Ca2+
Depot binding is said to occur when drugs - Correct answers✔✔Bind to inactive sites
During the ____ period, no additional action potentials can be created - Correct
answers✔✔Absolute refractory
Neural transmission is generally ____ within a single neuron and ____ between neurons. -
Correct answers✔✔Electrical; chemical
The most common type of synapse in the brain is the ______ synapse - Correct
answers✔✔Axodendritic
Neurons rely on ____ for protection, metabolic support and insulation - Correct answers✔✔Glial
cells
Which of the following factors does NOT affect the pharmokinetics of a drug?
A) Route of Administration
B) Lipid solubility
C) Depot binding
D) Drug action - Correct answers✔✔Drug action
,The sac-like structures in the presynaptic terminal are called ______ and are filled with _______
- Correct answers✔✔Synaptic vesicles; neurotransmitter molecules
In addition to environmental and sensory stimuli, psychoactive drugs can trigger long-lasting
changes in neuronal connectivity. Collectively, these changes are termed - Correct
answers✔✔Synaptic plasticity
Axonal transport of proteins occurs along a track formed by - Correct answers✔✔Microtubules
When activated, somatodendritic autoreceptors - Correct answers✔✔Reduce the rate of cell
firing
If a substance is a neurotransmitter, stimulation of the presynaptic cell should have the same
effect as - Correct answers✔✔Direct application of the proposed substance to the postsynaptic
cell
In order for a substance to be considered a neurotransmitter it must meet several criteria. Which
of the following is NOT considered a criterion for neurotransmitter status?
A) A synthetic mechanism should be present in the presynaptic cell
B) Vesicles containing the substance should move down the axon with the action potentials when
the neuron is stimulated
C) Receptors for the proposed substance should be present on the postsynaptic cell
D) A means for inactivating the substance should be present - Correct answers✔✔Vesicles
containing the substance should move down the axon with the action potentials when the neuron
is stimulated
The Na+/K+ pump helps to maintain the ______ by moving three Na+ ions in and two K+ ions
out of the cell - Correct answers✔✔Resting membrane potential
, Activating a metabotropic receptor can result in all of the following except for
A) Opening of a G protein-gated ion channel
B) changes in the levels of a second messenger
C)Opening of an ion channel within the receptor
D) Changes in gene expression - Correct answers✔✔Changes in gene expression
Drug metabolism mostly occurs in the ____ and usually makes a drug more _____ soluble. -
Correct answers✔✔Liver; Water
The ____ is best described as a result of the selective permeability of the neuronal membrane and
the uneven distribution of ions inside and outside the cell. - Correct answers✔✔Resting
membrane potential
After drug administration has occurred, the amount of drug in the blood that is free to bind at
specific target sites is/are referred to as - Correct answers✔✔Bioavailability
In the dose-response curve, a decrease in potency is indicated by a shift - Correct answers✔✔To
the right
_____ refer(s) to specific molecular changes that occur when a drug binds to a particular target
site or receptor, while ______ are the resulting widespread alterations in function. - Correct
answers✔✔Drug action; drug effects
Selective blockade of terminal autoreceptors for DA would lead to a(n) - Correct
answers✔✔Increase in neurotransmitter release
QUESTIONS AND CORRECT ANSWERS
The process of releasing neurotransmitter molecules from the vesicles is known as _____ and
occurs as a result of an influx of _____ - Correct answers✔✔Exocytosis; Ca2+
Depot binding is said to occur when drugs - Correct answers✔✔Bind to inactive sites
During the ____ period, no additional action potentials can be created - Correct
answers✔✔Absolute refractory
Neural transmission is generally ____ within a single neuron and ____ between neurons. -
Correct answers✔✔Electrical; chemical
The most common type of synapse in the brain is the ______ synapse - Correct
answers✔✔Axodendritic
Neurons rely on ____ for protection, metabolic support and insulation - Correct answers✔✔Glial
cells
Which of the following factors does NOT affect the pharmokinetics of a drug?
A) Route of Administration
B) Lipid solubility
C) Depot binding
D) Drug action - Correct answers✔✔Drug action
,The sac-like structures in the presynaptic terminal are called ______ and are filled with _______
- Correct answers✔✔Synaptic vesicles; neurotransmitter molecules
In addition to environmental and sensory stimuli, psychoactive drugs can trigger long-lasting
changes in neuronal connectivity. Collectively, these changes are termed - Correct
answers✔✔Synaptic plasticity
Axonal transport of proteins occurs along a track formed by - Correct answers✔✔Microtubules
When activated, somatodendritic autoreceptors - Correct answers✔✔Reduce the rate of cell
firing
If a substance is a neurotransmitter, stimulation of the presynaptic cell should have the same
effect as - Correct answers✔✔Direct application of the proposed substance to the postsynaptic
cell
In order for a substance to be considered a neurotransmitter it must meet several criteria. Which
of the following is NOT considered a criterion for neurotransmitter status?
A) A synthetic mechanism should be present in the presynaptic cell
B) Vesicles containing the substance should move down the axon with the action potentials when
the neuron is stimulated
C) Receptors for the proposed substance should be present on the postsynaptic cell
D) A means for inactivating the substance should be present - Correct answers✔✔Vesicles
containing the substance should move down the axon with the action potentials when the neuron
is stimulated
The Na+/K+ pump helps to maintain the ______ by moving three Na+ ions in and two K+ ions
out of the cell - Correct answers✔✔Resting membrane potential
, Activating a metabotropic receptor can result in all of the following except for
A) Opening of a G protein-gated ion channel
B) changes in the levels of a second messenger
C)Opening of an ion channel within the receptor
D) Changes in gene expression - Correct answers✔✔Changes in gene expression
Drug metabolism mostly occurs in the ____ and usually makes a drug more _____ soluble. -
Correct answers✔✔Liver; Water
The ____ is best described as a result of the selective permeability of the neuronal membrane and
the uneven distribution of ions inside and outside the cell. - Correct answers✔✔Resting
membrane potential
After drug administration has occurred, the amount of drug in the blood that is free to bind at
specific target sites is/are referred to as - Correct answers✔✔Bioavailability
In the dose-response curve, a decrease in potency is indicated by a shift - Correct answers✔✔To
the right
_____ refer(s) to specific molecular changes that occur when a drug binds to a particular target
site or receptor, while ______ are the resulting widespread alterations in function. - Correct
answers✔✔Drug action; drug effects
Selective blockade of terminal autoreceptors for DA would lead to a(n) - Correct
answers✔✔Increase in neurotransmitter release
