Answers.
C
Terms in this set (65)
1. coagulationcascade activation
2. Kinin system activation
cellular injury leads to: (5) 3. Mast cell degranulation
4. Complement cascade activation
5. chemotactic factors released
fibrin mesh containing the injury
traps microorganisms to prevent
Coagulation cascade activation
leads to (4) spread stops bleeding
plasmin-activates complement and kinin system
Bradykinin
released: pain
Kinin system activation leads to
(4) vasodilation/permeability
chemotaxis
MAC-lysis of bacteria
C2B--increased vasodilation and
Complement cascade activation
permeability C3a/C5a/C4a--
leads to (5)
triggers mast cell degranulation
C5a attracts neutrophils
C3b enhances opsonization
C2B does what? increases vasodilation and permeability
and is apart of what chain complement cascade activation
,MAC does what? lysis of bacteria
and is apart of what chain? complement cascade activation
C5a does what? Attracts neutrophils
and is apart of what chain? complement cascade activaton
C3b does what? Enhances opsonization
and is apart of what chain? complement cascade activation
attraction of neutrophils, eosinophils and monocytes
phagocytosis (leads to WBC death/rupture)
Chemotactic factors released
-Activates complement, kinin and coagulation cascade
leads to what?
monocytes present antigens and activate T/B cell immunity--
release cytokines Il 1, IL 6, TNF and growth factors
monocytes present antigens Chemotactic factors released
and activate T/B cell
immunity--release cytokines Il
1, IL 6, TNF and growth
factors
happens in which chain
Histam
ine
Mast cell degranulation leads to: cytoki
(5)
nes
leukotrienes
prostaglandins
platelet activating factor
vasodilation/increased
histamine does what? permeability increased blood
flow to site
local swelling/erythema
TNF--leukocyte emigration, inc permeability
cytokines do what (in mast cell IL 13--chemotaxis, B cell proliferation and
degranulation)
antibody productuon IL4--Bcel proliferation
and antibody production
Which interlukin is elevated IL4
early in inflammation?
, Which interlukin is IL 13
elevated later in
inflammation?
TNF released when in early and late
inflammation process?
Increase vascular permeability
function of leukotrines in mast chemotaxis of neutrophils, eosinophils and
cell degranulation
macrophages also known as slow
leukotrines also known as slow reaction substances of anaphyllaxis
___________________ and do
what to the inflammatory response prolong inflammatory response