MMSC 438 FINAL QUESTIONS AND ANSWERS
Cell wall synthesis inhibitors - Answer -Beta-lactams and glycopeptides
Beta lactams - Answer -penicillin and cephalosporins
Cephalexin and cephalothin are in what generation of cephalosporin? - Answer -1st
generation GP
Cefoxitin and cefotetan are what generation of cephalosporin? - Answer -2nd
generation GP and GN
Cefoxatime, cetriaxone and ceftazidime are what generation of cephalosporin? -
Answer -3rd generation GN
What generation of cephalosporin penetrates CSF? - Answer -third generation
Cefepime is what generation of cephalosporin? - Answer -fourth generation more GN
and many GP
What generation of cephalosporin has beta lactamase stability? - Answer -fourth
generation
What generation of cephalosporin has ceftaroline? - Answer -fifth generation
What generation of cephalosporin has active vs mrsa? - Answer -5th generation
Glycopeptides are gp only and involve the antibiotics - Answer -vancomycin and
teicoplanin
Plasma membrane damage mechanism involves - Answer -polypeptides
Antibiotics under plasma membrane inhibitors are - Answer -polymyxin and colistin
Type of inhibitor that contains these groups of antibiotics
Tetracycline
Macrolide
Chloromphenicol
Lincosamide
Aminoglycoside
Ketolide - Answer -protein synthesis
Macrolides - Answer -erythromycin and azithromycin
, Lincosomides - Answer -clindamycin
Aminoglycosides - Answer -Gentamicin
Inhibitor that involves
Quinolones
Metronidazole
Rifampin - Answer -nucleic acid synthesis inhibition
Inhibitor that involves
Sulfonamide and trimethoprim - Answer -metabolic pathway
Is a resistance that involved a horizontal transfer of a R plasmid - Answer -acquired
What type of bacteria produces beta lactamase - Answer -Gram negative
Decreased intracellular drug accumulation - Answer -efflux pumps
Altered metabolic pathway involves... - Answer -folic acid
AST standards - Answer -0.5 mcfarland standard= 1.5 x 10^8 cfu/ml
Qualitative AST - Answer -disk diffusion
Larger the zone the _________ MIC - Answer -smaller
Gradient strip and quantitative - Answer -ETEST
In this test the point where zone of inhibition intersects the strip is the MIC - Answer -
etest
Quality control organisms - Answer -S. Aureus
E.coli
P. Aeruginosa
Quality control is recommended each day but reduced to 1 day per week if acceptable
results for each antimicrobial obtained for - Answer -30 days
Broth dilution is qualitative or quantitative - Answer -quantitative
Kirby-Bauer Test is quanitative or qualitative - Answer -qualitative
What are anaerobes resistant to - Answer -aminoglycosides
RIPE is for what bacteria - Answer -mycobacteria
Cell wall synthesis inhibitors - Answer -Beta-lactams and glycopeptides
Beta lactams - Answer -penicillin and cephalosporins
Cephalexin and cephalothin are in what generation of cephalosporin? - Answer -1st
generation GP
Cefoxitin and cefotetan are what generation of cephalosporin? - Answer -2nd
generation GP and GN
Cefoxatime, cetriaxone and ceftazidime are what generation of cephalosporin? -
Answer -3rd generation GN
What generation of cephalosporin penetrates CSF? - Answer -third generation
Cefepime is what generation of cephalosporin? - Answer -fourth generation more GN
and many GP
What generation of cephalosporin has beta lactamase stability? - Answer -fourth
generation
What generation of cephalosporin has ceftaroline? - Answer -fifth generation
What generation of cephalosporin has active vs mrsa? - Answer -5th generation
Glycopeptides are gp only and involve the antibiotics - Answer -vancomycin and
teicoplanin
Plasma membrane damage mechanism involves - Answer -polypeptides
Antibiotics under plasma membrane inhibitors are - Answer -polymyxin and colistin
Type of inhibitor that contains these groups of antibiotics
Tetracycline
Macrolide
Chloromphenicol
Lincosamide
Aminoglycoside
Ketolide - Answer -protein synthesis
Macrolides - Answer -erythromycin and azithromycin
, Lincosomides - Answer -clindamycin
Aminoglycosides - Answer -Gentamicin
Inhibitor that involves
Quinolones
Metronidazole
Rifampin - Answer -nucleic acid synthesis inhibition
Inhibitor that involves
Sulfonamide and trimethoprim - Answer -metabolic pathway
Is a resistance that involved a horizontal transfer of a R plasmid - Answer -acquired
What type of bacteria produces beta lactamase - Answer -Gram negative
Decreased intracellular drug accumulation - Answer -efflux pumps
Altered metabolic pathway involves... - Answer -folic acid
AST standards - Answer -0.5 mcfarland standard= 1.5 x 10^8 cfu/ml
Qualitative AST - Answer -disk diffusion
Larger the zone the _________ MIC - Answer -smaller
Gradient strip and quantitative - Answer -ETEST
In this test the point where zone of inhibition intersects the strip is the MIC - Answer -
etest
Quality control organisms - Answer -S. Aureus
E.coli
P. Aeruginosa
Quality control is recommended each day but reduced to 1 day per week if acceptable
results for each antimicrobial obtained for - Answer -30 days
Broth dilution is qualitative or quantitative - Answer -quantitative
Kirby-Bauer Test is quanitative or qualitative - Answer -qualitative
What are anaerobes resistant to - Answer -aminoglycosides
RIPE is for what bacteria - Answer -mycobacteria
