CLEAR SUMMARY
Diphenhydramine class and action
Antihistamine via H1 antagonism
-anti-cholinergic
Diphenhydramine MOA
To treat allergic rhinitis, common cold, cough, sneezing,
pruritus, and urticaria
-prevent motion sickness
Diphenhydramine Contraindications
-acute asthma attack, severe liver disease
-COPD, neonate
Diphenhydramine caution
-Narrow-angle glaucoma, BPH, Urinary retention
-Breastfeeding, urinary retention
Diphenhydramine interaction
-increased CNS effect: alcohol, opioids, hypnotics,
barbiturates
-Avoid MAOIs
Diphenhydramine side effects and adverse effects
Side effects:
-CNS effects, agitation, insomnia
-Urinary retention, blurred vision, dry mouth and throat
-Hypotension, abdominal pain, constipation
-Photosensitivity, palpitations
Adverse reactions:
-none
,Life threatening:
-Agranulocytosis, hemolytic anemia, thrombocytopenia
Diphenhydramine nursing implications
-Baseline vitals
-drug history
-CBC
-cardiac and respiratory status
Diphenhydramine patient education
-avoid driving or operating heavy machinery is drowsiness
occurs
-Administer through IM into a large muscle
-Avoid SubQ
-avoid alcohol and other CNS depressants
Antitussive
a drug that prevents coughing
Dextromethorphan class and action
-Antitussive
-stops cough
Dextromethorphan MOAs
-Depresses cough center in medulla
Dextromethorphan indications
-nonproductive cough due to minor tract infections
-inhaled irritants
Dextromethorphan contraindications
hypersensitivity
Dextromethorphan caution
pregnancy, asthma/emphysema, hepatic disease
Dextromethorphan drug interaction
-Increase CNS depression: alcohol, antihistamines,
antidepressants, opiates
,-Hypotension and hyperpyrexia (body reaches temps of
106.7 F): MAOIs
Dextromethorphan side effects
-CNS effects
-Fatigue, GI distress
Dextromethorphan nursing implications
Dextromethorphan patient education
Lower Respiratory disorders
-COPD
-Restrictive lung disease
-Asthma
-Chronic bronchitis
-Bronchiectasis
-Emphysema
-Restrictive lung disease: decrease lung capacity due to
fluid in the lungs or loss of lung elasticity
Beta2-Adrenergic Agonists
Treat asthma by promoting bronchodilation
Albuterol class and action
Beta2 agonist/sympathomimetic - bronchodilation
Albuterol indications
asthma, bronchitis
Albuterol MOA
beta 2 agonist that relaxes the bronchial smooth muscle
-bronchodilation
Albuterol Contraindications
Hypersensitivity, milk protein hypersensitivity
Albuterol cautions
-Cardiac dysrhythmia, coronary
heart failure, cardiac disease, hypo/hyperthyroidism,
diabetes mellitus, rheumatoid arthritis, hypokalemia,
, hypocalcemia, older adults, seizures, MAOI therapy,
pregnancy
Albuterol interactions
Increased effect:
- sympathomimetics
- MAOIs, TCAs
Antagonize effect:
- beta blocker
Albuterol adverse reactions and side effects
Side effects:
-Tremors, CNS effects, agitation
-anxiety, sweating, HA
-Nasopharyngitis, insomnia, muscle cramps
- GI distress
Adverse reactions:
-palpitations, tachycardia, HTN, infection, hypokalemia
Albuterol life threatening effects
Cardiac dysrhythmias, angioedema, bronchospasm
-Steven-Johnson syndrome
Albuterol nursing implications
Albuterol patient education
Upper respiratory disorders
common cold, acute rhinitis, allergic rhinitis
Upper respiratory drug class
Antihistamine
Bronchodilator
Anticholinergic
Tiotropium class and action
-Anticholinergic
Tiotropium MOAs