Q&A FOR QUICK REVISION
Which drug is a Broad-Spectrum Penicillin?
Amoxicillin
MOA: amoxicilin
Inhibits bacterial cell wall synthesis by binding to penicillin-
binding proteins
Common way to remember penicillin drugs
Ending in "-cillin"
Uses of Amoxicillin
treats "-itisis" : Otitis media, sinusitis, tonsilitis, respiratory
and urinary tract infections, and gastric/duodenal ulcers
What are the four types of penicillins?
Basic, broad spectrum, penicillinase-resistant, extended
spectrum
Adverse Effects of amoxicillin
Hypersensitivity reactions (anaphylaxis), superinfection,
hepatic damage
Side effects of Amoxicillin
GI upset, rash, headache
Which organs need to be monitored with amoxicillin?
Hepatotoxicity and nephrotoxicity
what superinfections needs to be monitored with
amoxicillin?
Stomatitis and vaginitis
Nursing considerations for Amoxicillin
Labs: LFTs, BUN/creatinine; urinary output, assess for
allergy and superinfections
, Which drug is a 3rd Generation Cephalosporin
Ceftriaxone
MOA: Ceftriaxone
Inhibits cell wall synthesis; beta-lactamase resistant
Trade name of Ceftriaxone
Rocephin
What are the different groups of Cephalosporin
First, second, third, fourth, and futh generations
Use of Ceftriaxone
Gonorrhea, pneumonia, meningitis, surgical prophylaxis
Adverse effects of Ceftriaxone
Anaphylaxis, bleeding, nephrotoxicity
Side effects of Ceftriaxone
Diarrhea, nausea, injection site pain
Common way to remember Ceftriaxone and it's side
effects?
CCCD - Cephalosporin, Ceftriaxone, CDIFF, Drug
Interactions (disulfurum-like reactions)
What is a disulfurum-like reaction?
The body's inability to properly metabolize alcohol, leading
to a buildup of acetaldehyde, a toxic byproduct.
Superinfections of Ceftriaxone
Stomatitis, Anal/genital itching, CDIFF
Common way to remember what Ceftriaxone treats
Infections ending in "-itis"
Meningitis, appendicitis, etc
Which drug is a Macrolide?
Azithromycin
Easy way to remember what drugs are classified as
Macrolides
Ending in "-mycin"