NR 565 Final Exam with Accurate
Solutions
Antacids - ANSWER-Contraindicated in the presence of severe abdominal pain of
unknown cause, especially if accompanied by fever
Increase lower esophageal sphincter tone
Administration with other meds should be separated by at least 2 hours
Calcium based antacids - ANSWER-Contraindicated in the presence of hypercalcemia
and renal calculi
Magnesium based antacids - ANSWER-Contraindicated in patients with renal failure
Antidiarrheals Contraindication - ANSWER-toxic megacolon, especially in those with
inflammatory bowel disease
Bismuth subsalicylate (Pepto bismol): - ANSWER-Contraindicated in children or
teenagers during or after recovery from chickenpox or flu-like illness
Contraindicated for patients with ASA hypersensitivity
should be warned about gray/black stools and black tongue
diphenoxylate w/atropine (Lomotil): - ANSWER-contraindicates their use in narrow-
angle glaucoma and requires cautious use in prostatic hyperplasia
Use with extreme caution in children, not recommended for use in children younger than
12 y/o
Difenoxin w/atropine (Motofen): - ANSWER-The atropine component of diphenoxylate
and difenoxin contraindicates their use in narrow-angle glaucoma and requires cautious
use in prostatic hyperplasia.
Use with extreme caution in children, not recommended for use in children younger than
12 y/o
Sucralfate (Carafate): - ANSWER-Do not use with digoxin or warfarin
, Misoprostol (Cytotec): - ANSWER-Pregnancy X: Can produce uterine contractions
endangering pregnancy
Indicated for prophylaxis and treatment of duodenal ulcers associated with NSAID use
Phenothiazines: prochlorperazine (Compazine), perphenazine, promethazine
(Phenergan)
- ANSWER-Contraindicated in Parkinson's Disease
Contraindicated in narrow-angle glaucoma, bone marrow depression, and sever CVD or
hepatic disease
5-HT3 receptor agonists: palonosetron (Aloxi), dolasetron mesylate (Anzemet),
granisetron (Kytril, Sancuso) and ondansetron (Zofran)
- ANSWER-Contraindicated: pts w/ narrow angle glaucoma
NKI receptor antagonist: Aprepitant (Emend)
- ANSWER-Concurrent use of Aprepitant and pimozide, terfenadine, astemizole, or
cisapride is contraindicated due to potentially life-threatening reactions
Nizatidine and Ranitidine - ANSWER-DO NOT rx for patients w. hx of liver disease
Pt education: report black tarry stools
Prokinetics: metoclopramide (Reglan)
- ANSWER-BLACK BOX WARNING: risk for developing tardive dyskinesia
Contrindicated: in the presence of disorders in which stimulation of GI motility is
dangerous (GI hemorrhage, mechanical obstruction, new surgery on the GI tract, or
perforation),
PPI's - ANSWER-contraindication is hypersensitivity to ingredients
Co-administration of Plavix and Omeprazole - ANSWER-decreases effectiveness of
Plavix by 46%
use PPI w/ less CYP2C19 function such as dexlansoprazole, lansoprazole, and
pantoprazole
Laxatives - ANSWER-All share precautions for dependency
Common adverse reactions: excessive bowel activity, cramping, flatulence, and bloating
Solutions
Antacids - ANSWER-Contraindicated in the presence of severe abdominal pain of
unknown cause, especially if accompanied by fever
Increase lower esophageal sphincter tone
Administration with other meds should be separated by at least 2 hours
Calcium based antacids - ANSWER-Contraindicated in the presence of hypercalcemia
and renal calculi
Magnesium based antacids - ANSWER-Contraindicated in patients with renal failure
Antidiarrheals Contraindication - ANSWER-toxic megacolon, especially in those with
inflammatory bowel disease
Bismuth subsalicylate (Pepto bismol): - ANSWER-Contraindicated in children or
teenagers during or after recovery from chickenpox or flu-like illness
Contraindicated for patients with ASA hypersensitivity
should be warned about gray/black stools and black tongue
diphenoxylate w/atropine (Lomotil): - ANSWER-contraindicates their use in narrow-
angle glaucoma and requires cautious use in prostatic hyperplasia
Use with extreme caution in children, not recommended for use in children younger than
12 y/o
Difenoxin w/atropine (Motofen): - ANSWER-The atropine component of diphenoxylate
and difenoxin contraindicates their use in narrow-angle glaucoma and requires cautious
use in prostatic hyperplasia.
Use with extreme caution in children, not recommended for use in children younger than
12 y/o
Sucralfate (Carafate): - ANSWER-Do not use with digoxin or warfarin
, Misoprostol (Cytotec): - ANSWER-Pregnancy X: Can produce uterine contractions
endangering pregnancy
Indicated for prophylaxis and treatment of duodenal ulcers associated with NSAID use
Phenothiazines: prochlorperazine (Compazine), perphenazine, promethazine
(Phenergan)
- ANSWER-Contraindicated in Parkinson's Disease
Contraindicated in narrow-angle glaucoma, bone marrow depression, and sever CVD or
hepatic disease
5-HT3 receptor agonists: palonosetron (Aloxi), dolasetron mesylate (Anzemet),
granisetron (Kytril, Sancuso) and ondansetron (Zofran)
- ANSWER-Contraindicated: pts w/ narrow angle glaucoma
NKI receptor antagonist: Aprepitant (Emend)
- ANSWER-Concurrent use of Aprepitant and pimozide, terfenadine, astemizole, or
cisapride is contraindicated due to potentially life-threatening reactions
Nizatidine and Ranitidine - ANSWER-DO NOT rx for patients w. hx of liver disease
Pt education: report black tarry stools
Prokinetics: metoclopramide (Reglan)
- ANSWER-BLACK BOX WARNING: risk for developing tardive dyskinesia
Contrindicated: in the presence of disorders in which stimulation of GI motility is
dangerous (GI hemorrhage, mechanical obstruction, new surgery on the GI tract, or
perforation),
PPI's - ANSWER-contraindication is hypersensitivity to ingredients
Co-administration of Plavix and Omeprazole - ANSWER-decreases effectiveness of
Plavix by 46%
use PPI w/ less CYP2C19 function such as dexlansoprazole, lansoprazole, and
pantoprazole
Laxatives - ANSWER-All share precautions for dependency
Common adverse reactions: excessive bowel activity, cramping, flatulence, and bloating
