NR565- Advance Pharmacology Exam
with Accurate Solutions
II-V - correct Answer-Which schedule drugs can APRNs prescribe?
State Board of Nursing - correct Answer-Who determines and regulates prescriptive
authority?
Longer wait times to sign a prescription
Limit practitioners that are needed in rural areas
Unequal relationships between providers.
Independent practitioners= more patients being seen= lessens the patient/provider load
- correct Answer-How does limited prescriptive authority impact patients within the
healthcare system?
Safe and competent practice
Understanding of the drugs, reactions, and pharmacology
Be aware of the age group you are prescribing to - correct Answer-What are the key
responsibilities of prescribing?
Documented provider-patient relationship
Not prescribing for family or friends
Documenting a thorough H&P, including discussions with the patient, and drug
monitoring/titrating.
Cost, guidelines, availability, interactions, side effects, allergies, hepatic and renal
function, need for monitoring, and special populations - correct Answer-What should be
used to make prescribing decisions?
increase glomerular filtration rate leads to increase drug excretion
increase hepatic metabolism
decrease tone and motility of bowel
increase drug absorption - correct Answer-Be familiar with pharmacokinetic and
pharmacodynamic changes of older adults and how that would translate to baseline
information needed to prescribe.
Recommendations of medications inappropriate for elderly (65 and older)
Prevents adverse drug reactions - correct Answer-Beer's Criteria- What is it and Why is
it important
-increase risk for medication interactions - correct Answer-Impacts/outcomes of
polypharmacy
, inhibit metabolism, increase blood levels of medications
Examples
Valproate, isoniazid, sulfonamides, amiodarone, chloramphenicol, ketoconazole,
grapefruit juice, quinidine
"VISA credit card debt INHIBITS spending on designers like CK to look GQ" - correct
Answer-CYP450 inhibitors
o Examples
o What do they do?
o What do they cause if not used correctly? (aka: What would the patient experience?)
Speed up metabolism of drugs (drug is cleared faster), drug has lesser effect (decrease
blood levels of drug)
Examples
Barbituates, St John wort, Carbamazepine, rifampin, alcohol, phenytoin, griseofulvin,
phenobarbital, sulfonylureas
"Bullshit Crap GPS INDUCES rage" - correct Answer-Examples of CYP450 inducers
o Examples
o What do they do?
o What do they cause if not used correctly? (aka: What would the patient experience?)
medications metabolized slower, medication might not work or put them at risk for side-
effects - correct Answer-What happens when someone has a poor metabolism
phenotype?
Whether the drug is safe, effective, and benefits of a drug outweigh the risks - correct
Answer-What does the U.S. Food and Drug Administration regulate when it comes to
medications?
patients never filling/refilling prescriptions (resulting in therapeutic failure)
multiple chronic disorders
multiple prescription medications
multiple doses per day for each medication
drug packaging that is difficult to open
multiple prescribers
changes in the regimen (adding meds, changes in dose or timing)
cognitive or physical impairment (reduction in memory, hearing, visual, color, or manual
dexterity)
living alone
recent discharge from the hospital
low literacy
inability to pay for meds
personal conviction that a drug is unnecessary or the dosage is too high
presence of side effects - correct Answer-Reasons for medication non-adherence
with Accurate Solutions
II-V - correct Answer-Which schedule drugs can APRNs prescribe?
State Board of Nursing - correct Answer-Who determines and regulates prescriptive
authority?
Longer wait times to sign a prescription
Limit practitioners that are needed in rural areas
Unequal relationships between providers.
Independent practitioners= more patients being seen= lessens the patient/provider load
- correct Answer-How does limited prescriptive authority impact patients within the
healthcare system?
Safe and competent practice
Understanding of the drugs, reactions, and pharmacology
Be aware of the age group you are prescribing to - correct Answer-What are the key
responsibilities of prescribing?
Documented provider-patient relationship
Not prescribing for family or friends
Documenting a thorough H&P, including discussions with the patient, and drug
monitoring/titrating.
Cost, guidelines, availability, interactions, side effects, allergies, hepatic and renal
function, need for monitoring, and special populations - correct Answer-What should be
used to make prescribing decisions?
increase glomerular filtration rate leads to increase drug excretion
increase hepatic metabolism
decrease tone and motility of bowel
increase drug absorption - correct Answer-Be familiar with pharmacokinetic and
pharmacodynamic changes of older adults and how that would translate to baseline
information needed to prescribe.
Recommendations of medications inappropriate for elderly (65 and older)
Prevents adverse drug reactions - correct Answer-Beer's Criteria- What is it and Why is
it important
-increase risk for medication interactions - correct Answer-Impacts/outcomes of
polypharmacy
, inhibit metabolism, increase blood levels of medications
Examples
Valproate, isoniazid, sulfonamides, amiodarone, chloramphenicol, ketoconazole,
grapefruit juice, quinidine
"VISA credit card debt INHIBITS spending on designers like CK to look GQ" - correct
Answer-CYP450 inhibitors
o Examples
o What do they do?
o What do they cause if not used correctly? (aka: What would the patient experience?)
Speed up metabolism of drugs (drug is cleared faster), drug has lesser effect (decrease
blood levels of drug)
Examples
Barbituates, St John wort, Carbamazepine, rifampin, alcohol, phenytoin, griseofulvin,
phenobarbital, sulfonylureas
"Bullshit Crap GPS INDUCES rage" - correct Answer-Examples of CYP450 inducers
o Examples
o What do they do?
o What do they cause if not used correctly? (aka: What would the patient experience?)
medications metabolized slower, medication might not work or put them at risk for side-
effects - correct Answer-What happens when someone has a poor metabolism
phenotype?
Whether the drug is safe, effective, and benefits of a drug outweigh the risks - correct
Answer-What does the U.S. Food and Drug Administration regulate when it comes to
medications?
patients never filling/refilling prescriptions (resulting in therapeutic failure)
multiple chronic disorders
multiple prescription medications
multiple doses per day for each medication
drug packaging that is difficult to open
multiple prescribers
changes in the regimen (adding meds, changes in dose or timing)
cognitive or physical impairment (reduction in memory, hearing, visual, color, or manual
dexterity)
living alone
recent discharge from the hospital
low literacy
inability to pay for meds
personal conviction that a drug is unnecessary or the dosage is too high
presence of side effects - correct Answer-Reasons for medication non-adherence
