BSN 315 - Elimination/GI | Questions and Answers
Questions in this set (85)
Which condition is treated with a Gastric ulcer
histamine2 blocker? Histamine2 blockers are effective in treating gastric ulcers.
Select all that apply.
Duodenal ulcer
Gastric Histamine2 blockers are effective in treating duodenal ulcers.
carcinoma
Gastric ulcer Gastroesophageal reflux disease
Duodenal Histamine2 blockers are effective in treating gastroesophageal reflux disease.
ulcer
Gastroparesi
s
Gastroesophageal reflux disease
Which statement regarding the The elimination half-life of cimetidine is 1.5 to 2 hours.
pharmacodynamics of
cimetidine is accurate? Rationale for Incorrect:
Cimetidine has an onset of Cimetidine’s onset of action is expected within 30 minutes of
action of 15 minutes. administration, not 15 minutes.
Cimetidine’s duration of action is 8 The duration of action for cimetidine is 4 to 5 hours, not 8 to 12
to 12 hours. hours. It is dosed three to four times daily.
The drug reaches its peak effect in 2 Cimetidine reaches its peak concentration in 45 to 90 minutes, not 2 to 3
hours.
to 3 hours.
The elimination half-life of
cimetidine is
1.5 to 2 hours.
Which statement regarding the Cimetidine is primarily excreted in the urine.
pharmacokinetics of cimetidine is The histamine2 receptor antagonist, cimetidine, is primarily
accurate? Food enhances the excreted in the urine. Accumulation of the drug may occur in
absorption of cimetidine. patients with renal impairment.
Cimetidine readily and easily
crosses the blood-brain Rationale for Incorrect:
barrier. Food slows, not enhances, the absorption of cimetidine; however,
Cimetidine is primarily excreted the overall effect of cimetidine is not impacted.
in the urine. Cimetidine has difficulty crossing the blood-brain barrier.
The drug is not metabolized by the Cimetidine does, in fact, undergo metabolism by the liver.
liver.
,Which instructions would the nurse Just before meals and at bedtime.
provide Mr. Evans about when to Histamine2 receptor antagonists, such as cimetidine are to be taken
take the prescribed cimetidine? just before meals and at bedtime to decrease food-induced acid
secretion.
Case Study Details
Mr. Evans is a 47-year-old male
patient who came into the clinic
reporting an upset stomach with
heartburn. He reports he has
been having these symptoms
for a couple of weeks, and over-
the-counter therapy has not
helped. Mr. Evans reports
taking antacids on a daily
basis. Upon physical
assessment, the nurse determines
Mr. Evans is stable and that his
vital signs are within normal
limits. After assessing Mr. Evans,
the health care provider
prescribes cimetidine. Because
Mr. Evans has never taken
cimetidine before, the nurse needs
to teach him about his new
medication.
Just before meals and first thing
upon awakening in the morning.
Just before meals and at
bedtime. After meals and
first thing upon awakening
in the morning.
After meals and at bedtime.
Hepatic function
Before administering
The patient’s liver function must be assessed before administering cimetidine.
cimetidine to a 27- year-old
female patient, which patient
Renal function
parameter would a nurse ensure
The patient’s kidney function must be assessed before administering
has been assessed? cimetidine.
Select all that apply.
Pregnancy status
Hepatic Pregnancy status must be assessed in this female patient of
function childbearing age before receiving cimetidine.
Renal
function Fluid and electrolyte status
Thyroid Fluid and electrolyte status must be assessed before administering cimetidine.
function
Pregnancy
status
,Fluid and electrolyte status
Which respiratory complication Pneumonia
associated with cimetidine is a Pneumonia is a concern in patients receiving cimetidine. As the
concern, as the drug increases drug increases gastric pH, the risk for pneumonia also
gastric pH? increases.
Pneumonia
Asthma
attacks
Interstitial lung disease
Exacerbation of chronic
obstructive pulmonary
disease (COPD)
Which effect would a nurse Increased effect of phenytoin
anticipate may occur if a patient When taken together, cimetidine increases the concentration of
taking phenytoin is given phenytoin, thus increasing its effect. The patient must be
cimetidine? monitored closely to determine whether a dosage reduction in
Increased effect of phenytoin is warranted.
cimetidine Decreased effect
of cimetidine Increased
effect of phenytoin
Decreased effect of
phenytoin
, With which medical condition Kidney disease
would a nurse expect the Accumulation of cimetidine may occur with renal impairment, and a
health care provider to reduce dosage reduction is needed in these patients.
the dosage of cimetidine due
to potential accumulation of
the drug?
Kidney
disease
Crohn
disease
Diabetes
Cardiovascular disease
Which outcome is anticipated as a Decrease in hydrogen ions and gastric acid
result of histamine2 receptor The concentration of both hydrogen ions and gastric acid is
blockers obstructing histamine2 decreased when the histamine2 receptors are obstructed by
receptors in the parietal cells in histamine2 receptor blockers.
the stomach?
Increase in hydrogen ions and
gastric acid
Decrease in hydrogen ions and
gastric acid
Increase in hydrogen ions and
decrease in gastric acid
Decrease in hydrogen ions and
increase in gastric acid
Which teaching point will the “Breast enlargement and a reduction in libido may occur with
nurse provide a patient who is cimetidine.” Antiandrogenic effects such as decreased libido and
newly prescribed cimetidine for breast enlargement may occur with cimetidine. This is because
gastroesophageal reflux cimetidine binds to androgen receptors.
disease (GERD)? Discontinuation of therapy generally results in a reversal of these effects.
“Breast enlargement and a
reduction in libido may occur
with cimetidine.”
“The effects of a dose of
cimetidine last for about 12
hours.”
“The health care provider will
likely need to increase your
dose of theophylline while
you take cimetidine.”
“You can expect the drug to start
working in 15 minutes to reduce
your symptoms.”
Which patient would a nurse A 71-year-old patient with hypertension
determine will likely receive a A 71-year-old patient with hypertension will likely require a dosage
dosage reduction in cimetidine reduction due to the age of the patient. Older adults have less
for gastroesophageal reflux gastric acid and therefore do not need as high of doses of
Questions in this set (85)
Which condition is treated with a Gastric ulcer
histamine2 blocker? Histamine2 blockers are effective in treating gastric ulcers.
Select all that apply.
Duodenal ulcer
Gastric Histamine2 blockers are effective in treating duodenal ulcers.
carcinoma
Gastric ulcer Gastroesophageal reflux disease
Duodenal Histamine2 blockers are effective in treating gastroesophageal reflux disease.
ulcer
Gastroparesi
s
Gastroesophageal reflux disease
Which statement regarding the The elimination half-life of cimetidine is 1.5 to 2 hours.
pharmacodynamics of
cimetidine is accurate? Rationale for Incorrect:
Cimetidine has an onset of Cimetidine’s onset of action is expected within 30 minutes of
action of 15 minutes. administration, not 15 minutes.
Cimetidine’s duration of action is 8 The duration of action for cimetidine is 4 to 5 hours, not 8 to 12
to 12 hours. hours. It is dosed three to four times daily.
The drug reaches its peak effect in 2 Cimetidine reaches its peak concentration in 45 to 90 minutes, not 2 to 3
hours.
to 3 hours.
The elimination half-life of
cimetidine is
1.5 to 2 hours.
Which statement regarding the Cimetidine is primarily excreted in the urine.
pharmacokinetics of cimetidine is The histamine2 receptor antagonist, cimetidine, is primarily
accurate? Food enhances the excreted in the urine. Accumulation of the drug may occur in
absorption of cimetidine. patients with renal impairment.
Cimetidine readily and easily
crosses the blood-brain Rationale for Incorrect:
barrier. Food slows, not enhances, the absorption of cimetidine; however,
Cimetidine is primarily excreted the overall effect of cimetidine is not impacted.
in the urine. Cimetidine has difficulty crossing the blood-brain barrier.
The drug is not metabolized by the Cimetidine does, in fact, undergo metabolism by the liver.
liver.
,Which instructions would the nurse Just before meals and at bedtime.
provide Mr. Evans about when to Histamine2 receptor antagonists, such as cimetidine are to be taken
take the prescribed cimetidine? just before meals and at bedtime to decrease food-induced acid
secretion.
Case Study Details
Mr. Evans is a 47-year-old male
patient who came into the clinic
reporting an upset stomach with
heartburn. He reports he has
been having these symptoms
for a couple of weeks, and over-
the-counter therapy has not
helped. Mr. Evans reports
taking antacids on a daily
basis. Upon physical
assessment, the nurse determines
Mr. Evans is stable and that his
vital signs are within normal
limits. After assessing Mr. Evans,
the health care provider
prescribes cimetidine. Because
Mr. Evans has never taken
cimetidine before, the nurse needs
to teach him about his new
medication.
Just before meals and first thing
upon awakening in the morning.
Just before meals and at
bedtime. After meals and
first thing upon awakening
in the morning.
After meals and at bedtime.
Hepatic function
Before administering
The patient’s liver function must be assessed before administering cimetidine.
cimetidine to a 27- year-old
female patient, which patient
Renal function
parameter would a nurse ensure
The patient’s kidney function must be assessed before administering
has been assessed? cimetidine.
Select all that apply.
Pregnancy status
Hepatic Pregnancy status must be assessed in this female patient of
function childbearing age before receiving cimetidine.
Renal
function Fluid and electrolyte status
Thyroid Fluid and electrolyte status must be assessed before administering cimetidine.
function
Pregnancy
status
,Fluid and electrolyte status
Which respiratory complication Pneumonia
associated with cimetidine is a Pneumonia is a concern in patients receiving cimetidine. As the
concern, as the drug increases drug increases gastric pH, the risk for pneumonia also
gastric pH? increases.
Pneumonia
Asthma
attacks
Interstitial lung disease
Exacerbation of chronic
obstructive pulmonary
disease (COPD)
Which effect would a nurse Increased effect of phenytoin
anticipate may occur if a patient When taken together, cimetidine increases the concentration of
taking phenytoin is given phenytoin, thus increasing its effect. The patient must be
cimetidine? monitored closely to determine whether a dosage reduction in
Increased effect of phenytoin is warranted.
cimetidine Decreased effect
of cimetidine Increased
effect of phenytoin
Decreased effect of
phenytoin
, With which medical condition Kidney disease
would a nurse expect the Accumulation of cimetidine may occur with renal impairment, and a
health care provider to reduce dosage reduction is needed in these patients.
the dosage of cimetidine due
to potential accumulation of
the drug?
Kidney
disease
Crohn
disease
Diabetes
Cardiovascular disease
Which outcome is anticipated as a Decrease in hydrogen ions and gastric acid
result of histamine2 receptor The concentration of both hydrogen ions and gastric acid is
blockers obstructing histamine2 decreased when the histamine2 receptors are obstructed by
receptors in the parietal cells in histamine2 receptor blockers.
the stomach?
Increase in hydrogen ions and
gastric acid
Decrease in hydrogen ions and
gastric acid
Increase in hydrogen ions and
decrease in gastric acid
Decrease in hydrogen ions and
increase in gastric acid
Which teaching point will the “Breast enlargement and a reduction in libido may occur with
nurse provide a patient who is cimetidine.” Antiandrogenic effects such as decreased libido and
newly prescribed cimetidine for breast enlargement may occur with cimetidine. This is because
gastroesophageal reflux cimetidine binds to androgen receptors.
disease (GERD)? Discontinuation of therapy generally results in a reversal of these effects.
“Breast enlargement and a
reduction in libido may occur
with cimetidine.”
“The effects of a dose of
cimetidine last for about 12
hours.”
“The health care provider will
likely need to increase your
dose of theophylline while
you take cimetidine.”
“You can expect the drug to start
working in 15 minutes to reduce
your symptoms.”
Which patient would a nurse A 71-year-old patient with hypertension
determine will likely receive a A 71-year-old patient with hypertension will likely require a dosage
dosage reduction in cimetidine reduction due to the age of the patient. Older adults have less
for gastroesophageal reflux gastric acid and therefore do not need as high of doses of
